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Evidence-Based Analysis of the Critical Steps of Radical Cystectomy for Bladder Cancer

JOURNAL OF CLINICAL MEDICINE (2023)

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Summary: This study evaluated the feasibility and acceptability of a coordinated, multi-faceted prehabilitation program for patients with bladder cancer. The implementation of this comprehensive prehabilitation program at a high-volume bladder cancer referral center had a modest effect on resource consumption and complications.

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SWOG S1011: A phase III surgical trial to evaluate the benefit of a standard versus an extended lymphadenectomy performed at time of radical cystectomy for muscle invasive urothelial cancer.

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Summary: This study aimed to evaluate the impact of reproductive organ preservation strategies in surgical management of muscle invasive bladder cancer in women. The retrospective analysis showed that reproductive organ sparing surgery did not increase positive margin rates and did not decrease recurrence-free survival, cancer-specific survival, and overall survival.

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Summary: This study evaluated the health-related quality of life (HRQOL) of patients who underwent radical cystectomy (RC) for 24 months postoperatively. The study found that patients experienced favorable recovery in most areas of HRQOL, with scores returning to or exceeding baseline levels, except for sexual function and body image.

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Effect of Robot-Assisted Radical Cystectomy With Intracorporeal Urinary Diversion vs Open Radical Cystectomy on 90-Day Morbidity and Mortality Among Patients With Bladder Cancer A Randomized Clinical Trial

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Summary: This study compared the recovery and morbidity of patients undergoing robot-assisted radical cystectomy with intracorporeal reconstruction versus open radical cystectomy for bladder cancer. The results showed that robot-assisted surgery resulted in a statistically significant increase in the number of days alive and out of the hospital within 90 days of surgery. In addition, robot-assisted surgery had lower rates of thromboembolic and wound complications compared to open surgery. Patients who underwent robot-assisted surgery also reported better quality of life and less disability compared to those who underwent open surgery.

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Improving Estimates of Perioperative Morbidity After Radical Cystectomy Using the European Association of Urology Quality Criteria for Standardized Reporting and Introducing the Comprehensive Complication Index

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EUROPEAN UROLOGY (2020)

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EUROPEAN UROLOGY (2018)

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Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Freddie Bray et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2018)

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A Single-centre Early Phase Randomised Controlled Three-arm Trial of Open, Robotic, and Laparoscopic Radical Cystectomy (CORAL)

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EUROPEAN UROLOGY (2016)

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Impact of surgeon volume on the morbidity and costs of radical cystectomy in the USA: a contemporary population-based analysis

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BJU INTERNATIONAL (2015)

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EUROPEAN UROLOGY (2014)

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Prospective Randomized Controlled Trial of Robotic versus Open Radical Cystectomy for Bladder Cancer: Perioperative and Pathologic Results

Jeff Nix et al.

EUROPEAN UROLOGY (2010)

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Surgical factors influence bladder cancer outcomes: A cooperative group report

HW Herr et al.

JOURNAL OF CLINICAL ONCOLOGY (2004)

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