期刊
ACS BIOMATERIALS SCIENCE & ENGINEERING
卷 9, 期 10, 页码 5527-5547出版社
AMER CHEMICAL SOC
DOI: 10.1021/acsbiomaterials.3c00883
关键词
Hair Keratin; Hydrogel; Regenerative Medicine; Tissue Engineering; Clinical Translation
Regenerative medicine utilizes the regenerative potential of human cells to generate acceptable human tissues and organs, and biomaterial scaffolds play a vital role in this process. Hydrogels, especially keratin-based ones, are versatile materials for tissue engineering and regenerative medicine applications. This review focuses on the suitability and applications of keratin-based hydrogels in regenerative medicine.
Regenerative medicine (RM) is a multidisciplinary field that utilizes the inherent regenerative potential of human cells to generate functionally and physiologically acceptable human cells, tissues, and organs in vivo or ex vivo. An appropriate biomaterial scaffold with desired physicochemical properties constitutes an important component of a successful RM approach. Among various forms of biomaterials explored until the present day, hydrogels have emerged as a versatile candidate for tissue engineering and regenerative medicine (TERM) applications such as scaffolds for spatial patterning and delivering therapeutic agents, or substrates to enhance cell growth, differentiation, and migration. Although hydrogels can be prepared from a variety of synthetic polymers as well as biopolymers, the latter are preferred for their inherent biocompatibility. Specifically, keratins are fibrous proteins that have been recently explored for constructing hydrogels useful for RM purposes. The present review discusses the suitability of keratin-based biomaterials in RM, with a particular focus on human hair keratin hydrogels and their use in various RM applications.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据