The daily updated Dutch national database on COVID-19 epidemiology, vaccination and sewage surveillance

Article Infectious Diseases

Shorter serial intervals in SARS-CoV-2 cases with Omicron BA.1 variant compared with Delta variant, the Netherlands, 13 to 26 December 2021

Jantlen A. Backer et al.

Summary: The SARS- CoV-2 Omicron variant has a growth advantage over the Delta variant due to higher transmissibility, immune evasion, or a shorter serial interval.

EUROSURVEILLANCE (2022)

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Article Infectious Diseases

Sex differences in COVID-19 mortality in the Netherlands

Annabel Niessen et al.

Summary: This study provides a detailed description of sex differences in COVID-19 mortality in relation to age and comorbidities among cases, as well as in relation to age and sex-specific mortality in the general population of the Netherlands. The study confirms that male sex is a predisposing factor for severe outcomes of COVID-19, independent of age and comorbidities. COVID-19 specific mechanisms may contribute to this mortality discrepancy between males and females.

INFECTION (2022)

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Article Public, Environmental & Occupational Health

Risk of hospitalization and death for healthcare workers with COVID-19 in nine European countries, January 2020-January 2021

L. Ferland et al.

Summary: This article compares the attack rates of COVID-19 in healthcare workers and non-healthcare workers in nine European countries. The findings show that healthcare workers have higher attack rates of infection, hospitalization, and ICU admission compared to non-healthcare workers, but a relatively lower death rate. The differences may be attributed to better access to treatment, early detection of infection, and the healthy worker effect.

JOURNAL OF HOSPITAL INFECTION (2022)

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Article Public, Environmental & Occupational Health

Proximity to livestock farms and COVID-19 in the Netherlands, 2020-2021

Lenny Hogerwerf et al.

Summary: The study in the Netherlands found an association between living near livestock farms and individuals' SARS-CoV-2 status during 2020-2021, across different age groups and geographic areas.

INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH (2022)

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Article Biology

Regional importation and asymmetric within-country spread of SARS-CoV-2 variants of concern in the Netherlands

Alvin X. Han et al.

Summary: Flight restrictions had limited effectiveness in deterring VOC introductions due to the strength of regional land travel importation risks. In the Netherlands, the Alpha and Delta VOCs largely circulated within more populous regions with international connections before asymmetric bidirectional transmissions occurred with the rest of the country.

ELIFE (2022)

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Article Infectious Diseases

Impact of physical distancing measures against COVID-19 on contacts and mixing patterns: repeated cross-sectional surveys, the Netherlands, 2016-17, April 2020 and June 2020

Jantien A. Backer et al.

Summary: A survey conducted in the Netherlands showed that strict physical distancing measures significantly reduced community contact numbers, contributing to curbing the COVID-19 epidemic. Different age groups reacted differently after measures were relaxed, with children reverting to normal contact numbers and elderly individuals maintaining restricted contact levels.

EUROSURVEILLANCE (2021)

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Article Medicine, General & Internal

Testing behaviour and positivity for SARS-CoV-2 infection: insights from web-based participatory surveillance in the Netherlands

Scott A. McDonald et al.

Summary: Our study identified male sex, age groups <20, 50-64 years and 65+ years, diabetics, and sales/administrative employees as populations with lower propensity for testing but higher test positivity rates.

BMJ OPEN (2021)

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Article Biochemical Research Methods

Optimal vaccine allocation for COVID-19 in the Netherlands: A data-driven prioritization

Fuminari Miura et al.

PLoS Computational Biology (2021)

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Editorial Material Immunology

Associations Between Measures of Social Distancing and Severe Acute Respiratory Syndrome Coronavirus 2 Seropositivity: A Nationwide Population-based Study in the Netherlands

Eric R. A. Vos et al.

Summary: Physical distancing and indoor group size reductions are effective in reducing SARS-CoV-2 infection, with young adults potentially playing a significant role in viral spread compared to children under 12 years old who are permitted close contact.

CLINICAL INFECTIOUS DISEASES (2021)

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Article Public, Environmental & Occupational Health

Risk factors associated with the incidence of self-reported COVID-19-like illness: data from a web-based syndromic surveillance system in the Netherlands

Scott A. McDonald et al.

Summary: A study in the Netherlands found that males, individuals aged 65 and older, and those with higher education had a lower incidence rate of COVID-19-like illness, while factors such as smoking, asthma, allergies, and diabetes were associated with a higher incidence rate. Web-based syndromic surveillance proved useful for monitoring trends and risk factors associated with mild disease.

EPIDEMIOLOGY AND INFECTION (2021)

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Review Gastroenterology & Hepatology

Prevalence and Persistent Shedding of Fecal SARS-CoV-2 RNA in Patients With COVID-19 Infection: A Systematic Review and Meta-analysis

Yawen Zhang et al.

Summary: The study found that fecal SARS-CoV-2 RNA is commonly detected in COVID-19 patients with a 3-fold increased risk in patients with diarrhea. The shedding of fecal RNA lasted more than 3 weeks after presentation and a week after the last detectable respiratory RNA.

CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY (2021)

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Review Public, Environmental & Occupational Health

Characteristics of Viral Shedding Time in SARS-CoV-2 Infections: A Systematic Review and Meta-Analysis

Danying Yan et al.

Summary: The viral shedding time (VST) of SARS-CoV-2 varies among different demographic and clinical characteristics, with longer VSTs observed in symptomatic infections, infected adults, individuals with chronic diseases, and stool specimens.

FRONTIERS IN PUBLIC HEALTH (2021)

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Article Virology

Assignment of epidemiological lineages in an emerging pandemic using the pangolin tool

Aine O'Toole et al.

Summary: The global virus genomics community has responded unprecedentedly to the SARS-CoV-2 pandemic, leading to significant advances in 'real-time' generation and sharing of genomic data. The development of new analytical methods, such as pangolin, has been necessary to handle the rapid growth in virus genome data production. Pangolin has processed nearly two million virus genomes, aiding in SARS-CoV-2 genomic epidemiology and providing researchers with valuable information about the pandemic's transmission lineages.

VIRUS EVOLUTION (2021)

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Review Radiology, Nuclear Medicine & Medical Imaging

CO-RADS: Coronavirus Classification Review

Diana Penha et al.

Summary: In mid-January 2021, there were over 95 million diagnosed COVID-19 cases and approximately 2 million deaths globally. Changes in chest computed tomography images of COVID-19 cases requiring hospitalization or intensive care have shown improved sensitivity. The CO-RADS system, developed based on experiences from the first wave of the pandemic, demonstrates good observer reliability and performance in predicting moderate to severe disease.

JOURNAL OF CLINICAL IMAGING SCIENCE (2021)

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Letter Gastroenterology & Hepatology