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Bernard Lassegue et al.
CIRCULATION RESEARCH (2012)
Role of Nox4 in murine models of kidney disease
Andrea Babelova et al.
FREE RADICAL BIOLOGY AND MEDICINE (2012)
GLP-1 analog liraglutide protects against oxidative stress and albuminuria in streptozotocin-induced diabetic rats via protein kinase A-mediated inhibition of renal NAD(P)H oxidases
Hari Hendarto et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2012)
NADPH Oxidase 4 Mediates Insulin-Stimulated HIF-1α and VEGF Expression, and Angiogenesis In Vitro
Dan Meng et al.
PLOS ONE (2012)
Oxidative Stress, Nox Isoforms and Complications of Diabetes-Potential Targets for Novel Therapies
Mona Sedeek et al.
JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH (2012)
Chymase inhibition prevents myocardial fibrosis through the attenuation of NOX4-associated oxidative stress in diabetic hamsters
Yasutaka Maeda et al.
JOURNAL OF DIABETES INVESTIGATION (2012)
Abundance of TRPC6 protein in glomerular mesangial cells is decreased by ROS and PKC in diabetes
Sarabeth Graham et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2011)
A Glimpse of Various Pathogenetic Mechanisms of Diabetic Nephropathy
Yashpal S. Kanwar et al.
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 6 (2011)
Rosuvastatin improves endothelial function in db/db mice: role of angiotensin II type 1 receptors and oxidative stress
X. Y. Tian et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
Microvascular Modifications in Diabetic Retinopathy
Jennifer T. Durham et al.
CURRENT DIABETES REPORTS (2011)
New Insights into Redox-Modulated Cell Signaling
Gabriella Leonarduzzi et al.
CURRENT PHARMACEUTICAL DESIGN (2011)
Effect of lignin-derived lignophenols on vascular oxidative stress and inflammation in streptozotocin-induced diabetic rats
Yuuka Mukai et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2011)
Curcumin attenuates diabetic nephropathy by inhibiting PKC-α and PKC-β1 activity in streptozotocin-induced type I diabetic rats
Vivian Soetikno et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2011)
Regulation of NADPH Oxidase Activity Is Associated with miRNA-25-Mediated NOX4 Expression in Experimental Diabetic Nephropathy
Yibing Fu et al.
AMERICAN JOURNAL OF NEPHROLOGY (2010)
Oxidative stress and diabetic cardiovascular disorders: roles of mitochondria and NADPH oxidase
Garry X. Shen
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2010)
Nox4 is a Novel Inducible Source of Reactive Oxygen Species in Monocytes and Macrophages and Mediates Oxidized Low Density Lipoprotein-Induced Macrophage Death
Chi Fung Lee et al.
CIRCULATION RESEARCH (2010)
Inhibition of Reactive Oxygen Species by Lovastatin Downregulates Vascular Endothelial Growth Factor Expression and Ameliorates Blood-Retinal Barrier Breakdown in db/db Mice Role of NADPH Oxidase 4
Jingming Li et al.
DIABETES (2010)
AMP-activated Protein Kinase (AMPK) Negatively Regulates Nox4-dependent Activation of p53 and Epithelial Cell Apoptosis in Diabetes
Assaad A. Eid et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Effect of irreversibly glycated LDL in human vascular smooth muscle cells: lipid loading, oxidative and inflammatory stress
Anca V. Sima et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2010)
Ezetimibe Ameliorates Cardiovascular Complications and Hepatic Steatosis in Obese and Type 2 Diabetic db/db Mice
Masaya Fukuda et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)
NAD(P)H Oxidase Mediates TGF-beta 1-Induced Activation of Kidney Myofibroblasts
Corry D. Bondi et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2010)
Diabetic cardiomyopathy, causes and effects
Sihem Boudina et al.
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS (2010)
NADPH Oxidase versus Mitochondria-Derived ROS in Glucose-Induced Apoptosis of Pericytes in Early Diabetic Retinopathy
Nik M. Mustapha et al.
JOURNAL OF OPHTHALMOLOGY (2010)
Post-Stroke Inhibition of Induced NADPH Oxidase Type 4 Prevents Oxidative Stress and Neurodegeneration
Christoph Kleinschnitz et al.
PLOS BIOLOGY (2010)
Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney: implications in type 2 diabetic nephropathy
M. Sedeek et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2010)
Nox4 NADPH oxidase mediates oxidative stress and apoptosis caused by TNF-α in cerebral vascular endothelial cells
Shyamali Basuroy et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2009)
Dominant-negative p38 alpha mitogen-activated protein kinase prevents cardiac apoptosis and remodeling after streptozotocin-induced diabetes mellitus
Rajarajan A. Thandavarayan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2009)
NOX Enzymes in the Central Nervous System: From Signaling to Disease
Silvia Sorce et al.
ANTIOXIDANTS & REDOX SIGNALING (2009)
Effects of Angiotensin Receptor Blocker on Oxidative Stress and Cardio-Renal Function in Streptozotocin-Induced Diabetic Rats
Wawaimuli Arozal et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2009)
Identification of a Retinal Aldosterone System and the Protective Effects of Mineralocorticoid Receptor Antagonism on Retinal Vascular Pathology
Jennifer L. Wilkinson Berka et al.
CIRCULATION RESEARCH (2009)
Poldip2, a Novel Regulator of Nox4 and Cytoskeletal Integrity in Vascular Smooth Muscle Cells
Alicia N. Lyle et al.
CIRCULATION RESEARCH (2009)
Mechanisms of Podocyte Injury in Diabetes Role of Cytochrome P450 and NADPH Oxidases
Assaad A. Eid et al.
DIABETES (2009)
Ameliorative effect of berberine on endothelial dysfunction in diabetic rats induced by high-fat diet and streptozotocin
Chunmei Wang et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2009)
Subcellular localization of Nox4 and regulation in diabetes
Karen Block et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Tks5-Dependent, Nox-Mediated Generation of Reactive Oxygen Species Is Necessary for Invadopodia Formation
Begona Diaz et al.
SCIENCE SIGNALING (2009)
Insulin-like growth factor-I induces reactive oxygen species production and cell migration through Nox4 and Rac1 in vascular smooth muscle cells
Dan Meng et al.
CARDIOVASCULAR RESEARCH (2008)
Diabetic nephropathy: Mechanisms of renal disease progression
Yashpal S. Kanwar et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2008)
Enhanced expression of NADPH oxidase Nox4 in human gliomas and its roles in cell proliferation and survival
Tadahisa Shono et al.
INTERNATIONAL JOURNAL OF CANCER (2008)
Nox4 NAD(P)H oxidase mediates Src-dependent tyrosine phosphorylation of PDK-1 in response to angiotensin II - Role in mesangial cell hypertrophy and fibronectin expression
Karen Block et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Suppressing renal NADPH oxidase to treat diabetic nephropathy
Akihiro Tojo et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2007)
Pitavastatin ameliorates albuminuria and renal mesangial expansion by downregulating NOX4 in db/db mice
M. Fujii et al.
KIDNEY INTERNATIONAL (2007)
The Rho-kinase inhibitor, fasudil, attenuates diabetic nephropathy in streptozotocin-induced diabetic rats
Atsushi Gojo et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2007)
The PPARγ ligand, rosiglitazone, reduces vascular oxidative stress and NADPH oxidase expression in diabetic mice
Jinah Hwang et al.
VASCULAR PHARMACOLOGY (2007)
Reactive oxygen species-selective regulation of aortic inflammatory gene expression in Type 2 diabetes
Alejandra San Martin et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)
Increased oxidative stress in the streptozotocin-induced diabetic apoE-deficient mouse: Changes in expression of NADPH oxidase subunits and eNOS
Hong Ding et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2007)
Endothelial nitric oxide synthase uncoupling impairs endothelial progenitor cell mobilization and function in diabetes
Thomas Thum et al.
DIABETES (2007)
The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
Karen Bedard et al.
PHYSIOLOGICAL REVIEWS (2007)
Nox4 is required for maintenance of the differentiated vascular smooth muscle cell phenotype
Roza E. Clempus et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)
Reduction of diabetes-induced oxidative stress, fibrotic cytokine expression, and renal dysfunction in protein kinase Cβ -: Null mice
Yuzuru Ohshiro et al.
DIABETES (2006)
NADPH oxidases in cardiovascular health and disease
Alison C. Cave et al.
ANTIOXIDANTS & REDOX SIGNALING (2006)
Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases
KD Martyn et al.
CELLULAR SIGNALLING (2006)
Nox4 NAD(P)H oxidase mediates hypertrophy and fibronectin expression in the diabetic kidney
Y Gorin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
NAD(P)H oxidase 4 mediates transforming growth factor-β1-induced differentiation of cardiac fibroblasts into myofibroblasts
I Cucoranu et al.
CIRCULATION RESEARCH (2005)
Point mutations in the proline-rich region of p22phox are dominant inhibitors of Nox1- and Nox2-dependent reactive oxygen generation
T Kawahara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Differential effects of diabetes on the expression of the gp91phox homologues nox1 and nox4
MC Wendt et al.
FREE RADICAL BIOLOGY AND MEDICINE (2005)
Neuronal expression of the NADPH oxidase NOX4, and its regulation in mouse experimental brain ischemia
P Vallet et al.
NEUROSCIENCE (2005)
Mechanism of Ca2+ activation of the NADPH oxidase 5 (NOX5)
B Bánfi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
TGF-β1 and angiotensin networking in cardiac remodeling
S Rosenkranz
CARDIOVASCULAR RESEARCH (2004)
NOX3, a superoxide-generating NADPH oxidase of the inner ear
B Bánfi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Expression of Nox4 in osteoclasts
S Yang et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2004)
Increased expression of NAD(P)H oxidase subunits, NOX4 and p22phox, in the kidney of streptozotocin-induced diabetic rats and its reversibity by interventive insulin treatment
T Etoh et al.
DIABETOLOGIA (2003)
Two novel proteins activate superoxide generation by the NADPH oxidase NOX1
B Bánfi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Micro albuminuria in type 1 and type 2 diabetes mellitus: Evidence with angiotensin converting enzyme inhibitors and angiotensin II receptor blockers for treating early and preventing clinical nephropathy
HH Parving et al.
CURRENT HYPERTENSION REPORTS (2002)
Kruppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling
T Shindo et al.
NATURE MEDICINE (2002)
Oxidative stress and nitric oxide synthase in rat diabetic nephropathy: Effects of ACEI and ARB
ML Onozato et al.
KIDNEY INTERNATIONAL (2002)
A Ca2+-activated NADPH oxidase in testis, spleen, and lymph nodes
B Bánfi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
BM Brenner et al.
NEW ENGLAND JOURNAL OF MEDICINE (2001)
Redox-sensitve intermediates mediate angiotensin II-induced p38 MAP kinase activation, AP-1 binding activity, and TGF-β expression in adult ventricular cardiomyocytes
S Wenzel et al.
FASEB JOURNAL (2001)
Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family
X De Deken et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Identification of Renox, an NAD(P)H oxidase in kidney
M Geiszt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
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