4.4 Article

Does Preoperative Modic Changes Influence the Short-term Fusion Rate of Single Level Transforaminal Lumbar Interbody Fusion?-a Matched-pair Case Control Study

期刊

ORTHOPAEDIC SURGERY
卷 15, 期 9, 页码 2309-2317

出版社

WILEY
DOI: 10.1111/os.13795

关键词

Lumbar degenerative disease; Modic changes; Nano-hydroxyapatite; polyamide 66; Polyetheretherketone; Transforaminal lumbar interbody fusion

向作者/读者索取更多资源

This study aimed to compare the short-term fusion rate of lumbar degenerative disease patients with and without Modic changes (MCs) after single level transforaminal lumbar interbody fusion (TLIF). The results showed that the bony fusion rates and cage union ratios were significantly lower in the MCs group compared to the non MCs group. The fusion performance of n-HA/PA66 and PEEK cages in the MCs group was comparable.
ObjectiveAt present, the influence of Modic changes (MCs) on postoperative fusion rate of lumbar interbody fusion (LIF) is mainly focused on the medium- and long-term fusion rate, while the short-term fusion rate has not been reported. The aim of this study was to compare the short-term fusion rate of lumbar degenerative disease patients with and without MCs after single level transforaminal lumbar interbody fusion (TLIF). MethodsIn this retrospective and matched-pair case control study, we included 100 patients who underwent TLIF from January 2017 to January 2020 and had at least two follow-up visits over a two-year period. Fifty patients with MCs (MCs group) were matched with 50 patients without MCs (non MCs group) for age, sex, surgical level, diagnosis, operative time, and intraoperative blood loss. We collected the X-ray and computed tomography (CT) data of patients from 3 months to 2 years after the operation to assess bony fusion and the cage union ratio. According to the type of cage, the MCs group was further divided into the nano-hydroxyapatite/polyamide 66 (n-HA/PA66) group and polyetheretherketone (PEEK) group, and the fusion performance between the two groups was compared. Finally, age, sex, body mass index (BMI), smoking and cage type were included in the logistic regression model for risk factor analysis. ResultsThe bony fusion rates in the MCs group at 3 months, 6 months, 1 year and 2 years after surgery were significantly lower than those in the non MCs group (P < 0.05) (23.8% vs 62.5%, 52.6% vs 78.9%, 61.1% vs 83.3%, 74.0% vs 90.0%). The average coronal cage union ratios of the upper and lower endplates in the MCs group were significantly lower than those in the non MCs group (54.3% & PLUSMN; 17.5% vs 75.0% & PLUSMN; 17.2%, P < 0.05; 73.3% & PLUSMN; 12.0% vs 84.9% & PLUSMN; 8.0%, P < 0.05). Similarly, analogous results were obtained by comparing the MCs and non MCs groups' three-dimensional CT sagittal plane images (62.5% & PLUSMN; 16.5% vs 76.1% & PLUSMN; 12.4%, P < 0.05; 67.0% & PLUSMN; 13.9% vs 79.8% & PLUSMN; 11.5%, P < 0.05). ConclusionShort-term fusion rates were lower in the MCs group than in the non MCs group. The coronal and sagittal cage union ratio in the MCs group was lower than that in the non MCs group. The fusion performance of n-HA/PA66 and PEEK cages in the MCs group was comparable.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.4
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据