期刊
NATURAL PRODUCT RESEARCH
卷 31, 期 3, 页码 253-260出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2016.1230114
关键词
Paeonia suffruticosa Andrews; phenones; nitric oxide
资金
- National Natural Science Foundation of China [81430095]
- Ph.D. Programs Foundation of Ministry of Education of China [20132134110006]
- Applied Basic and Advanced Research Program of Tianjin [16JCYBJC27900]
Thirteen phenones were obtained from the 70% ethanol extract of Paeonia suffruticosa Andrews. Their structures were determined on the basis of chemical methods and spectral data. Among them, compound 1 was identified as a new compound, and compounds 5 and 13 were obtained from genus Paeonia for the first time. The inhibitory effects of isolated compounds (1-12) on nitric oxide (NO) production in lipopolysaccharide-activated macrophages were evaluated, and NO production was suppressed significantly by compound 7. [GRAPHICS] .
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