☆ 4.8 Article

Increased gut permeability and bacterial translocation are associated with fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome: implications for disease-related biomarker discovery

FRONTIERS IN IMMUNOLOGY (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Neurosciences

In Schizophrenia, Chronic Fatigue Syndrome- and Fibromyalgia-Like Symptoms are Driven by Breakdown of the Paracellular Pathway with Increased Zonulin and Immune Activation-Associated Neurotoxicity

Michael Maes et al.

Summary: This study aims to investigate the association between FF symptoms in schizophrenia and the breakdown of the paracellular pathway, zonulin, lowered natural IgM responses to oxidative specific epitopes (OSEs), and the BCPS-worsening index. Results showed that FF symptoms were correlated with paracellular pathway breakdown, pro-inflammatory cytokines, zonulin, IgA levels to TRYCATs, and inversely correlated with IgM levels to OSEs. It is concluded that physio-somatic symptoms of schizophrenia are driven by various pathways, including increased zonulin, breakdown of the paracellular tight-junctions pathway, immune activation, and neurotoxicity.

CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2023)

添加到收藏夹

Article Orthopedics

Investigating the association between the symptoms of women with Fibromyalgia, Digestive function, and markers of the microbiota of the Gastrointestinal Tract (The FIDGIT Study): study protocol

Sharon Erdrich et al.

Summary: This is a prospective study examining the interactions between digestive function, human gene expression, and the gut microbiome in relation to fibromyalgia. The study aims to gather data and samples to explore factors associated with fibromyalgia, with the goal of improving management of this condition.

BMC MUSCULOSKELETAL DISORDERS (2023)

添加到收藏夹

Article Microbiology

Deficient butyrate-producing capacity in the gut microbiome is associated with bacterial network disturbances and fatigue symptoms in ME/CFS

Cheng Guo et al.

Summary: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by unexplained debilitating fatigue, cognitive dysfunction, gastrointestinal disturbances, and orthostatic intolerance. A multi-omic analysis of 106 cases and 91 healthy controls revealed differences in gut microbiome diversity, abundances, functional pathways, and interactions in ME/CFS. Reduction in Faecalibacterium prausnitzii and Eubacterium rectale, health-promoting butyrate producers, was observed in ME/CFS.

CELL HOST & MICROBE (2023)

添加到收藏夹

Review Biochemistry & Molecular Biology

Towards a Better Understanding of the Complexities of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Long COVID

Warren P. Tate et al.

Summary: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex condition that occurs in susceptible individuals, often triggered by viral infections or other stressful events. The underlying factors are both genetic and environmental, although not well understood. The lack of an accessible molecular diagnostic test complicates diagnosis, but a common core set of neurological symptoms has been identified. The individualized responses to available treatments highlight the need for better classification and personalized therapeutic options.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

添加到收藏夹

Article Gastroenterology & Hepatology

Comorbid extra-intestinal central sensitization conditions worsen irritable bowel syndrome in primary care patients

Xiao Jing Wang et al.

Summary: This study investigated the relationship between central sensitization syndrome (CSS) diagnoses, quality of life, symptom severity, and interactions with healthcare providers in rural community populations. The findings showed that patients with IBS often have multiple CSS disorders, which increases symptom severity and lowers quality of life. Therefore, treating multiple CSS diagnoses as a global condition may improve patient experience.

NEUROGASTROENTEROLOGY AND MOTILITY (2023)

添加到收藏夹

Review Biochemistry & Molecular Biology

Fibromyalgia and Irritable Bowel Syndrome Interaction: A Possible Role for Gut Microbiota and Gut-Brain Axis

Cinzia Garofalo et al.

Summary: Fibromyalgia and Irritable Bowel Syndrome share similar symptoms and may have a common etiology related to alterations in gut microbiota. This review will discuss the similarities between FM and IBS and the potential therapeutic approaches based on microbiota manipulations.

BIOMEDICINES (2023)

添加到收藏夹

Article

Suppressed immune and metabolic responses to intestinal damage-associated microbial translocation in myalgic encephalomyelitis/chronic fatigue syndrome

Melanie Uhde et al.

Brain Behavior Immunity Health (2023)

添加到收藏夹

Review Biochemistry & Molecular Biology

Gut dysbiosis in severe mental illness and chronic fatigue: a novel trans-diagnostic construct? A systematic review and meta-analysis

Jenelle Marcelle Safadi et al.

Summary: Reduced gut-microbial diversity, or gut dysbiosis, has been linked to an anhedonic/amotivational syndrome, or sickness behavior, in patients with severe mental disorders and chronic fatigue. Elevated levels of proxy biomarkers of gut dysbiosis were found in patients compared to healthy controls, and these markers were positively correlated with the severity of sickness behavior. Further research comparing trans-diagnostic and categorical approaches is necessary for potential advancement in treatment for these conditions.

MOLECULAR PSYCHIATRY (2022)

添加到收藏夹

Review Immunology

The Gut Microbiome in Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS)

Rahel S. Konig et al.

Summary: Myalgic encephalomyelitis (ME) or Chronic Fatigue Syndrome (CFS) is a neglected, debilitating disease with unclear etiology and pathophysiology. The gut microbiome may play a role in CFS and further research is needed to explore potential diagnostic and therapeutic approaches.

FRONTIERS IN IMMUNOLOGY (2022)

添加到收藏夹

Review Rheumatology

The economic burden of fibromyalgia: A systematic literature review

Martina D'Onghia et al.

Summary: This review summarizes the available evidence on the economic impact of fibromyalgia and the specific cost drivers of healthcare expenditure for this syndrome. The findings suggest that fibromyalgia represents a substantial economic burden to healthcare systems and society. Medications were found to contribute significantly to the overall expenditures.

SEMINARS IN ARTHRITIS AND RHEUMATISM (2022)

添加到收藏夹

Review Medicine, General & Internal

A Correlation Between the Pathogenic Processes of Fibromyalgia and Irritable Bowel Syndrome in the Middle-Aged Population: A Systematic Review

Carla Valencia et al.

Summary: Irritable bowel syndrome (IBS) and fibromyalgia syndrome (FMS) are two common diseases, especially prevalent in the female population. There are some similar pathophysiological mechanisms involved in both conditions, including the immune system, mast cells, inflammatory cells, serotonin, and microbiota. Common associated factors include fatigue, pain, hypersensitivity, depression, and anxiety. Serotonin and mast cells are considered to be the main factors in the common pathogenesis of these two diseases, but mechanisms such as dysregulation of the microbiota and the gut-brain axis may also play important roles.

CUREUS JOURNAL OF MEDICAL SCIENCE (2022)

添加到收藏夹

Editorial Material Medicine, General & Internal

Will COVID-19 Lead to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome?

Anthony L. Komaroff et al.

FRONTIERS IN MEDICINE (2021)

添加到收藏夹

Review Medicine, General & Internal

The Emerging Role of Gut Microbiota in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Current Evidence and Potential Therapeutic Applications

Angelica Varesi et al.

Summary: Common symptoms of ME/CFS include pain, cognitive dysfunction, and fatigue, with gastrointestinal problems also frequently reported. Research has shown significant alterations in the gut microbiota of ME/CFS patients, which may contribute to worsening symptoms.

JOURNAL OF CLINICAL MEDICINE (2021)

添加到收藏夹

Article Medicine, General & Internal

Shadow Burden of Undiagnosed Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) on Society: Retrospective and Prospective-In Light of COVID-19

Diana Araja et al.

Summary: ME/CFS is a complex disorder with severe fatigue and other symptoms, causing substantial reductions in functional activity and quality of life. The study investigates undiagnosed ME/CFS patients, with a focus on potential post-viral CFS as a consequence of COVID-19. Results show that former COVID-19 patients report more anxiety and fatigue symptoms compared to ME/CFS patients and undiagnosed patients.

JOURNAL OF CLINICAL MEDICINE (2021)

添加到收藏夹

Article Medicine, General & Internal

European Network on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (EUROMENE): Expert Consensus on the Diagnosis, Service Provision, and Care of People with ME/CFS in Europe

Luis Nacul et al.

Summary: EUROMENE, funded by COST from 2016 to 2020, aims to assess healthcare delivery for individuals with ME/CFS in European countries. The network consists of clinicians, researchers, and health professionals from 22 countries working to improve care for people with ME/CFS.

MEDICINA-LITHUANIA (2021)

添加到收藏夹

Article Clinical Neurology

Chronic fatigue syndrome (CFS)/Myalgic Encephalomyelitis (ME) and Fibromyalgia (FM): the foundation of a relationship

Pamela G. Mckay et al.

Summary: Chronic fatigue syndrome (CFS)/Myalgic Encephalomyelitis (ME) and fibromyalgia (FM) may be related, as patients often experience debilitating symptoms such as fatigue and pain that impact their quality of life, requiring further research to confirm and explore this relationship.

BRITISH JOURNAL OF PAIN (2021)

添加到收藏夹

Review Orthopedics

Determining the association between fibromyalgia, the gut microbiome and its biomarkers: A systematic review

Sharon Erdrich et al.

BMC MUSCULOSKELETAL DISORDERS (2020)

添加到收藏夹

Article Medicine, Research & Experimental

From IBS to ME - The dysbiotic march hypothesis

Arnold Berstad et al.

MEDICAL HYPOTHESES (2020)

添加到收藏夹

Article Pharmacology & Pharmacy

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Fibromyalgia: Definitions, Similarities, and Differences

Benjamin H. Natelson

CLINICAL THERAPEUTICS (2019)

添加到收藏夹

Review Endocrinology & Metabolism

Myalgic encephalomyelitis or chronic fatigue syndrome: how could the illness develop?

Gerwyn Morris et al.

METABOLIC BRAIN DISEASE (2019)

添加到收藏夹

Article Endocrinology & Metabolism

The GC-MS metabolomics signature in patients with fibromyalgia syndrome directs to dysbiosis as an aspect contributing factor of FMS pathophysiology

Bontle G. Malatji et al.

METABOLOMICS (2019)

添加到收藏夹

Article Anesthesiology

Altered microbiome composition in individuals with fibromyalgia

Amir Minerbi et al.

PAIN (2019)

添加到收藏夹

Article Immunology

Cellular Immune Function in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

Jacqueline M. Cliff et al.

FRONTIERS IN IMMUNOLOGY (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics

Dorottya Nagy-Szakal et al.

SCIENTIFIC REPORTS (2018)

添加到收藏夹

Review Chemistry, Medicinal

Recognizing the Leaky Gut as a Trans-diagnostic Target for Neuroimmune Disorders Using Clinical Chemistry and Molecular Immunology Assays

Denitsa Simeonova et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2018)

添加到收藏夹

Article Medicine, Research & Experimental

Evaluation of four clinical laboratory parameters for the diagnosis of myalgic encephalomyelitis

Kenny L. De Meirleir et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2018)

添加到收藏夹

Article Microbiology

Fecal metagenomic profiles in subgroups of patients with myalgic encephalomyelitis/chronic fatigue syndrome

Dorottya Nagy-Szakal et al.

MICROBIOME (2017)

添加到收藏夹

Article Clinical Neurology

A diagnostic biomarker profile for fibromyalgia syndrome based on an NMR metabolomics study of selected patients and controls

Bontle G. Malatji et al.

BMC NEUROLOGY (2017)

添加到收藏夹

Article Pediatrics

Cow's milk protein intolerance in adolescents and young adults with chronic fatigue syndrome

Peter C. Rowe et al.

ACTA PAEDIATRICA (2016)

添加到收藏夹

Review Pharmacology & Pharmacy

The Role of Microbiota and Intestinal Permeability in the Pathophysiology of Autoimmune and Neuroimmune Processes with an Emphasis on Inflammatory Bowel Disease Type 1 Diabetes and Chronic Fatigue Syndrome

Gerwyn Morris et al.

CURRENT PHARMACEUTICAL DESIGN (2016)

添加到收藏夹

Article Microbiology

Reduced diversity and altered composition of the gut microbiome in individuals with myalgic encephalomyelitis/chronic fatigue syndrome

Ludovic Giloteaux et al.

MICROBIOME (2016)

添加到收藏夹

Review Medicine, General & Internal

A Role for the Intestinal Microbiota and Virome in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)?

Navena Navaneetharaja et al.

JOURNAL OF CLINICAL MEDICINE (2016)

添加到收藏夹

Article Multidisciplinary Sciences

Changes in Gut and Plasma Microbiome following Exercise Challenge in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

Sanjay K. Shukla et al.

PLOS ONE (2015)

添加到收藏夹

Review Neurosciences

The Emerging Role of Autoimmunity in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/cfs)

Gerwyn Morris et al.

MOLECULAR NEUROBIOLOGY (2014)

添加到收藏夹

Article Food Science & Technology

Consumption of cows' milk is associated with lower risk of type 2 diabetes mellitus. A cross-sectional study

Sonsoles Morcillo et al.

INTERNATIONAL DAIRY JOURNAL (2012)

添加到收藏夹

Article Medicine, General & Internal

COMPASS 31: A Refined and Abbreviated Composite Autonomic Symptom Score

David M. Sletten et al.

MAYO CLINIC PROCEEDINGS (2012)

添加到收藏夹

Review Medicine, General & Internal

Myalgic encephalomyelitis: International Consensus Criteria

B. M. Carruthers et al.

JOURNAL OF INTERNAL MEDICINE (2011)

添加到收藏夹

Review Nutrition & Dietetics

Gut inflammation in chronic fatigue syndrome

Shaheen E. Lakhan et al.

NUTRITION & METABOLISM (2010)

添加到收藏夹

Article Rheumatology

The American College of Rheumatology Preliminary Diagnostic Criteria for Fibromyalgia and Measurement of Symptom Severity

Frederick Wolfe et al.

ARTHRITIS CARE & RESEARCH (2010)

添加到收藏夹

Article Gastroenterology & Hepatology

Alterations in intestinal microbial flora and human disease

Mohamed Othman et al.

CURRENT OPINION IN GASTROENTEROLOGY (2008)

添加到收藏夹

Article Rheumatology

Altered intestinal permeability in patients with primary fibromyalgia and in patients with complex regional pain syndrome

A. Goebel et al.

RHEUMATOLOGY (2008)

添加到收藏夹

Article Clinical Neurology

Increased serum IgA and IgM against LPS of enterobacteria in chronic fatigue syndrome (CFS): Indication for the involvement of gram-negative enterobacteria in the etiology of CFS and for the presence of an increased gut-intestinal permeability

Michael Maes et al.

JOURNAL OF AFFECTIVE DISORDERS (2007)

添加到收藏夹

Article Rheumatology

A link between irritable bowel syndrome and fibromyalgia may be related to findings on lactulose breath testing

M Pimentel et al.

ANNALS OF THE RHEUMATIC DISEASES (2004)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.