Mechanisms of exercise in the treatment of lung cancer - a mini-review

Lung cancer constitutes a formidable menace to global health and well-being, as its incidence and mortality rate escalate at an alarming pace. In recent years, research has indicated that exercise has potential roles in both the prevention and treatment of lung cancer. However, the exact mechanism of the coordinating effect of exercise on lung cancer treatment is unclear, limiting the use of exercise in clinical practice. The purpose of this review is to explore the mechanisms through which exercise exerts its anticancer effects against lung cancer. This review will analyze the biological basis of exercise's anticancer effects on lung cancer, with a focus on aspects such as the tumor microenvironment, matrix regulation, apoptosis and angiogenesis. Finally, we will discuss future research directions and potential clinical applications.

Automated summary

Lung cancer is a major threat to global health, with increasing incidence and mortality rates. Exercise has been found to have potential roles in both prevention and treatment of lung cancer. However, the exact mechanisms of exercise's effects on lung cancer treatment are not clear, limiting its use in clinical practice. This review aims to explore the mechanisms through which exercise exerts its anticancer effects against lung cancer, focusing on aspects such as the tumor microenvironment, matrix regulation, apoptosis, and angiogenesis. Future research directions and potential clinical applications will also be discussed.