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Article
Allergy
Renal Disease and Systemic Sclerosis: an Update on Scleroderma Renal Crisis
Alice Cole et al.
Summary: Scleroderma renal crisis (SRC) is a life-threatening complication of systemic sclerosis (SSc) with a high mortality rate. Although angiotensin-converting enzyme inhibitor therapy has improved renal outcomes, there are currently no preventative measures and patients may rapidly decline. Studies have identified specific phenotypes at higher risk of developing SRC and novel urinary biomarkers may aid in early identification and treatment. Clear guidelines for management have been established to standardize care and promote collaboration between rheumatology and renal physicians. While outcomes following renal transplant have improved, further research is needed to understand the mechanisms and develop new therapies for SRC.
CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY (2023)
Review
Immunology
Posterior reversible encephalopathy syndrome: A neuropsychiatric manifestation of systemic lupus erythematosus
Martin Valdez-Lopez et al.
Summary: Posterior Reversible Encephalopathy Syndrome (PRES) is an acute neurological syndrome characterized by seizures, altered mental status, headache, and visual disturbances. It is often associated with Systemic Lupus Erythematosus (SLE), with SLE causing alterations in pathways implicated in the development of PRES. This suggests that PRES in the setting of SLE may be considered a distinct neuropsychiatric syndrome.
AUTOIMMUNITY REVIEWS (2021)
Article
Medicine, Research & Experimental
Systemic lupus erythematosus complicated with reversible posterior encephalopathy syndrome: a case report
Dong-Lin Hao et al.
Summary: The article presents a case of a 28-year-old female patient hospitalized due to intermittent fever and other symptoms, diagnosed with systemic lupus erythematosus (SLE) with reversible posterior encephalopathy syndrome (RPES) based on MRI findings. Treatment involves controlling blood pressure and aggressively treating the primary disease.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH (2021)