☆ 4.6 Review

Magnetic Nanoparticles as Mediators for Magnetic Hyperthermia Therapy Applications: A Status Review

APPLIED SCIENCES-BASEL (2023)

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Article Biochemistry & Molecular Biology

Computational Assessment of Magnetic Nanoparticle Targeting Efficiency in a Simplified Circle of Willis Arterial Model

Rodward L. Hewlin et al.

Summary: This paper presents the methodology and computational results of simulated medical drug targeting (MDT) via induced magnetism for administering patient-specific doses of therapeutic agents in a Circle of Willis (CoW) model. The computational model analyzes pulsatile blood flow, particle motion, and particle capture efficiency using magnetite (Fe3O4) and equations describing magnetic forces. The simulations demonstrate that higher particle capture efficiency is achieved for larger particle diameters and weaker magnetic fields, suggesting MDT as a possible treatment for cardiovascular disease.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

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Article Chemistry, Physical

Macrophage-mediated delivery of magnetic nanoparticles for enhanced magnetic resonance imaging and magnetothermal therapy of solid tumors

Fengfeng Xue et al.

Summary: Magnetothermal therapy (MHT) is a promising non-/minimal invasive and efficient approach for tumor treatment. However, the development of small MHT agents (< 50 nm) with excellent magnetothermal conversion performance and high tumor enrichment remains challenging. In this study, a macrophage-mediated delivery system was designed for enhanced magnetic resonance imaging (MRI) and MHT of solid tumors using small Fe@Fe3O4-DHCA nanoparticles. The aggregation of Fe@Fe3O4-DHCA nanoparticles in macrophages resulted in enhanced MRI and magnetothermal performance in vitro. Moreover, the in vivo MHT effect of macrophages loaded with Fe@Fe3O4-DHCA was superior to that of Fe@Fe3O4-DHCA alone, attributed to the tumor-targeting capability of macrophages. This macrophage-mediated delivery system presents a new strategy for enhanced MHT based on Fe@Fe3O4-DHCA nanoparticles, with great potential for clinical tumor therapy.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2023)

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Article Pharmacology & Pharmacy

Synthesis and characterization of a new gold-coated magnetic nanoparticle decorated with a thiol-containing dendrimer for targeted drug delivery, hyperthermia treatment and enhancement of MRI contrast agent

Zahra Zamani Nori et al.

Summary: A unique multi-functional magnetic nanocarrier containing thiol groups was designed and applied in drug delivery, hyperthermia, and as a contrast agent in MRI. The nanocarrier was prepared by modifying Fe3-delta O4@Au magnetic nanoparticles with a thiol-ended dendrimer. The nanocarrier can release an anticancer drug specifically in the reductive environment of cancer cells, and it has been demonstrated to have therapeutic efficiency in vitro.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2023)

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Article Materials Science, Multidisciplinary

The SLP estimation of the nanoparticle systems using size-dependent magnetic properties for the magnetic hyperthermia therapy

Sandeep Nain et al.

Summary: Magnetic Nanoparticle hyperthermia (MNH) is a hyperthermia therapy that uses magnetic nanoparticles to achieve temperature increase in tumor tissue/targeted region. This study investigates the effects of magnetic nanoparticle properties, size, and magnetic field parameters on heat generation during MNH. Comparisons of heat generation by three nanoparticle systems and its dependency on size and magnetic field parameters are theoretically investigated.

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS (2023)

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Review Pharmacology & Pharmacy

Magnetic iron oxide nanoparticles for brain imaging and drug delivery

Ruirui Qiao et al.

Summary: Central nervous system (CNS) disorders affect 1.5 billion people globally. With the advent of nanotechnologies, controlled delivery of drugs with magnetic iron oxide nanoparticles (MIONPs) holds promise in overcoming the blood-brain barrier and improving treatment efficacy. This review summarizes the recent advances and challenges in using MIONP-based platforms for brain imaging and drug delivery.

ADVANCED DRUG DELIVERY REVIEWS (2023)

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Article Materials Science, Ceramics

Morphology, structural and magnetic study of superparamagnetic Mg0.5Zn0.5Fe2-xLaxO4 (0 ≤ x ≤ 0.1) ferrite nanoparticles synthesized by chemical coprecipitation method

Rohit Ranga et al.

Summary: Lanthanum doped magnesium-zinc spinel ferrite samples were synthesized by the co-precipitation method. The effects of La3+ ion doping on crystallite size and lattice parameter were discussed. The samples showed a crystallite size range of 7-12 nm, percentage porosity range of 49-50%, and percentage crystallinity range of 80-85%. FTIR spectra shift to higher region with La3+ ion doping. EDS analysis confirmed the absence of impurities except carbon. EPR analysis showed a decrease in g-value and a shift in resonance field for the synthesized samples. The synthesized samples exhibited superparamagnetic nature and low coercive field value, making them suitable for ferrofluids and hyperthermia treatment applications.

CERAMICS INTERNATIONAL (2023)

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Article Chemistry, Physical

Effect on magnetic behaviour of Ag and Cd doped cobalt ferrite nanoparticles prepared by glycine-assisted sol-gel auto combustion method

T. Jayakumar et al.

Summary: Nanocomposites of AgxCdxCo1-2xFe2O4 were prepared by glycine-assisted Sol-gel derived auto combustion technique. The synthesized samples were analyzed by XRD, SEM, FT-IR, UV-visible spectrum, and VSM. The results showed the formation of a single-phase cubic spinel structure with particle sizes of 14-19 nm. The optical band gap energies varied with Ag/Cd concentration and the composites showed magnetic behavior suitable for magnetic storage applications.

JOURNAL OF ALLOYS AND COMPOUNDS (2023)

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Review Pharmacology & Pharmacy

Theranostic magnetic nanoparticles: Synthesis, properties, toxicity, and emerging trends for biomedical applications

Aseem Setia et al.

Summary: Nanotechnology provides nanotheranostics for real-time monitoring and treatment of diseases. Theranostic nanomedicine must overcome immune system destruction and target specific organs. Magnetic nanoparticles (MNPs) are used for non-invasive diagnostic imaging and have potential toxicity issues. Various methods have been used for MNP production, including biosynthetic techniques. MNPs have shown biocompatibility and acceptable safety profiles. Diagnostic imaging can be performed using different approaches, and the article discusses the manufacturing and development of theranostic magnetic nanosystems for therapeutic and diagnostic use.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2023)

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Article Physics, Condensed Matter

Hybrid Au/Co nanoparticles: Laser-assisted synthesis and applications in magnetic hyperthermia

Imran Ali et al.

Summary: Developing contamination-free techniques for synthesizing nanostructures, especially bimetallic nanoparticles for hyperthermia applications has been a recent focus of attention. Au/Co nanoparticles were synthesized using pulsed Nd:YAG laser ablation in distilled water, which is simple, rapid, environmentally friendly, and contamination-free. The synthesized nanoparticles were spherical in shape, 15 nm in size, and showed magnetic hyperthermia potential.

PHYSICA B-CONDENSED MATTER (2023)

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Article Chemistry, Analytical

Design and Development of a Traveling Wave Ferro-Microfluidic Device and System Rig for Potential Magnetophoretic Cell Separation and Sorting in a Water-Based Ferrofluid

Rodward L. Hewlin Jr et al.

Summary: This paper presents the design and development of a simple traveling wave ferro-microfluidic device for manipulating and separating cells in water-based ferrofluids. The paper describes the customization of cobalt ferrite nanoparticles, the development of a ferro-microfluidic device for separating cells and magnetic nanoparticles, the creation of a water-based ferrofluid with magnetic and non-magnetic particles, and the design of a system rig for magnetizing and manipulating non-magnetic particles in the ferro-microfluidic channel. The results demonstrate successful magnetophoretic manipulation and separation of particles in the ferro-microfluidic device.

MICROMACHINES (2023)

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Review Biochemistry & Molecular Biology

Metallic Nanoparticles: Their Potential Role in Breast Cancer Immunotherapy via Trained Immunity Provocation

Elham Zarenezhad et al.

Summary: Due to drawbacks in current cancer therapies, such as surgery, chemotherapy, and radiotherapy, developing more reliable, low toxic, cost-effective, and specific approaches like immunotherapy is crucial. Breast cancer is a major cause of morbidity and mortality with developed anticancer resistance. This study aimed to investigate the efficacy of metallic nanoparticles (MNPs)-based breast cancer immunotherapy, focusing on trained immunity provocation or innate immunity adaptation.

BIOMEDICINES (2023)

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Article Chemistry, Inorganic & Nuclear

Enhancement of antibacterial and anticancer properties lanthanum insight into zinc oxide nanoparticles prepared via coprecipitation process

G. Senthilkumar et al.

Summary: The development of La-doped ZnO nanoparticles shows promise in improving the biocidal properties of nanomaterials for medical applications in treating MDR bacteria and breast cancer. The nanomaterials were synthesized using a co-precipitation process and characterized using various techniques including XRD, FTIR, SEM, EDAX, UV-Vis spectroscopy, and PL experiments. The results demonstrated that the La-doped ZnO nanoparticles exhibited enhanced antibacterial activity and anticancer activity compared to ZnO nanoparticles alone.

INORGANIC CHEMISTRY COMMUNICATIONS (2023)

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Article Materials Science, Multidisciplinary

Obtention of magnetite nanoparticles via the hydrothermal method and effect of synthesis parameters

Julia Meller Mendes Silva et al.

Summary: In this study, nanomagnetite was synthesized through hydrothermal method with variation in temperature, reaction time and molar ratio. Statistical analysis revealed that longer reaction time resulted in smaller magnetite particle sizes. The purest samples obtained at a reaction temperature of 214℃ and reaction time of 6 hours exhibited ferromagnetic behavior and showed potential as drug delivery systems.

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS (2023)

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Article Chemistry, Physical

Magnetic nanoparticles covered with polycyclic aromatic hydrocarbons as singlet oxygen carriers for combining photodynamic therapy and magnetic hyperthermia

I. N. Ferreira et al.

Summary: Researchers developed hybrid nanoparticles with a magnetic core and a polycyclic aromatic hydrocarbon (PAH) shell for improved cancer and infectious disease therapies. The PAH shell can capture, store, and deliver singlet oxygen (O-1(2)) on demand, while the magnetic core generates heat via magnetic hyperthermia. The nanoparticles have the potential to be used for developing new therapies.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY (2023)

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Article Materials Science, Multidisciplinary

Ferroelectric, dielectric, magnetic and photocatalytic properties of Mn doped Ca-hexaferrite prepared via microemulsion route

Hafiz M. Umair et al.

Summary: The effect of Mn doping on the properties of CaMnxFe12-xO19 (x = 0.00, 0.10, 0.15, 0.20, 0.25, 0.30) was investigated. The samples exhibited a monophasic hexagonal structure and had an average crystallite size in the range of 21.16 nm-33.79 nm. As the Mn doping concentration increased, the dielectric loss decreased. The Mn-doped samples showed enhanced photocatalytic activity compared to the pristine CaFe12O19, with a degradation rate of 90% within 100 min of irradiation.

MATERIALS CHEMISTRY AND PHYSICS (2023)

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Article Materials Science, Multidisciplinary

Feasibility of superparamagnetic NiFe2O4 and GO-NiFe2O4 nanoparticles for magnetic hyperthermia

Aya Gasser et al.

Summary: Superparamagnetic Ni-ferrite and their composite with graphene oxide nanoparticles were successfully synthesized using a simple hydrothermal method. The synthesized materials exhibited superparamagnetic behavior with promising magnetic and thermal properties, making them potential candidates for hyperthermia therapy. The findings of this study open up new possibilities for the future applications of NiFe2O4 and GO-NiFe2O4 nanoparticles in hyperthermia.

MATERIALS SCIENCE AND ENGINEERING B-ADVANCED FUNCTIONAL SOLID-STATE MATERIALS (2023)

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Article Multidisciplinary Sciences

Investigation of optical, electrical and magnetic properties of hematite a-Fe2O3 nanoparticles via sol-gel and co-precipitation method

Muhammad Tahir et al.

Summary: Hematite nanoparticles were synthesized using co-precipitation and sol-gel methods. The structural properties of the synthesized nanoparticles were analyzed using X-ray diffraction (XRD) and the morphological structure was studied using scanning electron microscopy (SEM). The crystal size and unit cell volume were determined, and the X-ray density, optical band gap energy, electrical characteristics, and magnetic parameters of the samples were investigated. The results indicate that these materials have potential applications in catalysis, sensors, and water purification.

JOURNAL OF KING SAUD UNIVERSITY SCIENCE (2023)

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Review Materials Science, Ceramics

NiCu-silica nanoparticles as a potential drug delivery system

Janja Stergar et al.

Summary: In this study, we investigated the potential of NiCu magnetic nanoparticles as bimodal therapeutic systems, capable of simultaneous magnetic hyperthermia and targeted drug delivery. Superparamagnetic NixCu1-x nanoparticles were prepared using a sol-gel method and had a Curie temperature in the therapeutic range for use in magnetic hyperthermia. The release of model drugs from the nanoparticles was studied using an in vitro release system and quantified using UV-visible spectrophotometry. The nanoparticles were characterized using various techniques and their biocompatibility was tested on human skin-derived fibroblasts.

JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY (2022)

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Article Nanoscience & Nanotechnology

Magnetic Biohybrid Microrobot Multimers Based on Chlorella Cells for Enhanced Targeted Drug Delivery

De Gong et al.

Summary: This study proposes a strategy of magnetic biohybrid microrobot multimers (BMMs) based on Chlorella for targeted drug delivery. The microrobot units, magnetized Chlorella cells loaded with doxorubicin, can reconfigure into chain-like BMMs via attraction-induced self-assembly and disassemble reversibly via repulsion. These BMMs exhibit diverse swimming modes and high maneuverability, demonstrating great potential for targeted anticancer therapy.

ACS APPLIED MATERIALS & INTERFACES (2022)

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Article Chemistry, Multidisciplinary

Magnetic hyperthermia: Potentials and limitations

Mozhdeh Peiravi et al.

Summary: Magnetic hyperthermia therapy, using magnetic nanoparticles as heat intermediaries for cancer treatment, faces challenges in controlling local tumor temperature and enhancing nanoparticles heating power.

JOURNAL OF THE INDIAN CHEMICAL SOCIETY (2022)

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Review Biology

Nanomaterials-based hyperthermia: A literature review from concept to applications in chemistry and biomedicine

Leila Farzin et al.

Summary: Hyperthermia, the use of mild elevation of temperature, has the potential to enhance the effects of radiotherapy and chemotherapy in cancer treatment. However, the main challenge is to heat malignant cells effectively without damaging healthy tissues. Despite these challenges, hyperthermia shows promise as a treatment modality and has attracted research interest.

JOURNAL OF THERMAL BIOLOGY (2022)

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Article Materials Science, Multidisciplinary

Microfluidic synthesis of magnetic nanoparticles in droplet-based microreactors

Lei Zou et al.

Summary: Microfluidic devices are widely used for the controlled synthesis of various nanomaterials through continuous microreactors. In this study, magnetic nanoparticles were synthesized using droplet-based continuous microreactors in a microfluidic chip. The size and properties of nanoparticles were investigated by varying the flow rate and temperature of the aqueous and oil streams. The efficient chemical reaction initiated by fusing two aqueous droplets showed superior results compared to conventional methods for synthesizing Fe3O4 nanoparticles.

MATERIALS CHEMISTRY AND PHYSICS (2022)

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Article Materials Science, Multidisciplinary

Synthesis and characterization of PEG coated hollow Fe3O4 magnetic nanoparticles as a drug carrier

Xianhong Da et al.

Summary: The hollow Fe3O4 magnetic nanorings and nanotubes have better drug loading capacity and are more suitable for drug carriers compared with nanospheres.

MATERIALS LETTERS (2022)

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Article Chemistry, Physical

Nanoparticles: From synthesis to applications and beyond

Atida Selmani et al.

Summary: This review summarizes the current trends in nanoparticle synthesis and characterization and discusses the stability of nanoparticles in different media and their interactions with interfaces. It also provides an overview of nanoparticle applications and explores future prospects.

ADVANCES IN COLLOID AND INTERFACE SCIENCE (2022)

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Article Materials Science, Multidisciplinary

Superparamagnetic cobalt nanoparticles in hyperbranched polyester polyol matrix with anti-protease activity

Artur A. Khannanov et al.

Summary: In this study, a new type of cobalt nanoparticles with a core-shell structure was obtained in a matrix of a hyperbranched polyester polyol. The cobalt nanoparticles showed superparamagnetic properties and had a blocking temperature of 305 K. They exhibited inhibitory effects on the activity of the secretory aspartic protease Candida albicans and had low hemolytic activity. These findings suggest that the cobalt nanoparticles embedded in the hyperbranched polyester polyol matrix have potential applications in medicine.

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS (2022)

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Article Chemistry, Multidisciplinary

Engineering in modern medicine using 'magnetic nanoparticles' in understanding physicochemical interactions at the nano-bio interfaces

Y-S Borghei et al.

Summary: Magnetic nanoparticles (MNPs) have biomedical applications that can be classified based on their unique properties in the presence or removal of an external magnetic field. Magnetite nanoparticles, with their unique physicochemical and catalytic properties, have gained increasing attention in medical fields for diagnosis, imaging, therapy, and cellular/tissue engineering.

MATERIALS TODAY CHEMISTRY (2022)

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Article Materials Science, Multidisciplinary

Synthesis of ZnFe2O4 nanoparticles with different morphologies via thermal decomposition approach and studies on their magnetic properties

Dimpal Tomar et al.

Summary: In this study, zinc ferrite nanoparticles with various morphologies were synthesized by thermal decomposition of Zn-Fe glycolates prepared under different synthetic conditions. The nanoparticles were characterized using different analytical techniques and their magnetic properties were investigated.

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS (2022)

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Article Materials Science, Ceramics

Tuning specific loss power of CoFe2O4 nanoparticles by changing surfactant concentration in a combined co-precipitation and thermal decomposition method

Kamran Heydaryan et al.

Summary: A new synthetic approach was used to produce high-quality CoFe2O4 nanoparticles with adjustable magnetic, morphological, and structural properties by varying the surfactant concentration, offering potential for controlled magnetic hyperthermia.

CERAMICS INTERNATIONAL (2022)

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Review Biotechnology & Applied Microbiology

Applications of Metallic Nanoparticles in the Skin Cancer Treatment

Mahrokh Marzi et al.

Summary: Skin cancer is a major global concern and nanoparticles have shown promise as drug delivery systems in its treatment, improving therapeutic outcomes and reducing side effects.

BIOMED RESEARCH INTERNATIONAL (2022)

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Article Biophysics

Design of functionalized magnetic silica multi-core composite nanoparticles for synergistic magnetic hyperthermia/radiotherapy in cancer cells

Hailei Lin et al.

Summary: Nanomaterials, especially magnetic nanoparticles (MNPs), have great potential for cancer treatment due to their unique properties. In this study, Fe3O4@SiO2@Sec(2)@FA nanoparticles were designed as a novel nano-radiosensitizer to enhance the therapeutic effects of radiotherapy. These nanoparticles exhibited good heat generation efficiency and active targeting, making them suitable for magnetic hyperthermia/radiotherapy.

COLLOIDS AND SURFACES B-BIOINTERFACES (2022)

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Article Engineering, Chemical

Synthesis and effect on the surface morphology & magnetic properties of ferrimagnetic nanoparticles by different wet chemical synthesis methods

Abhishek Kumar et al.

Summary: In this study, ferrimagnetic nanoparticles (FMNPs) were synthesized using different wet chemical synthesis methods. The influence of different synthesis methods on the structural and magnetic properties of FMNPs was explored. The results showed that FMNPs obtained through chemical co-precipitation method exhibited a stable cubical shape with smaller size, while FMNPs prepared by hydrothermal method showed higher magnetic strength and suitable particle size distribution. Additionally, the chemical co-precipitation method was found to be more cost-effective and time-efficient.

POWDER TECHNOLOGY (2022)

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Review Infectious Diseases

Nickel Nanoparticles: Applications and Antimicrobial Role against Methicillin-Resistant Staphylococcus aureus Infections

Elham Zarenezhad et al.

Summary: Methicillin-resistant Staphylococcus aureus (MRSA) has developed extensive antibiotic resistance and contains virulence factors for severe infections. Nickel nanoparticles (NiNPs) have shown potential as a cheap prognostic and therapeutic agent, exerting antibacterial effects through disrupting cell membranes, deforming proteins, and inhibiting DNA replication.

ANTIBIOTICS-BASEL (2022)

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Review Chemistry, Physical

Multifunctional surface functionalized magnetic iron oxide nanoparticles for biomedical applications: A review

Rutuja Prashant Gambhir et al.

Summary: This review explores the extensive use of magnetic iron oxide nanoparticle-based multifunctional platforms in biomedical applications. The modifications and integrations of IONPs with various entities make them suitable for a wide range of biomedical fields. The review also covers recent advances in multifunctional IONPs, including biosensing, pathogen detection, MRI, gene therapy, chemotherapy, drug delivery, bioimaging, stem cell detection, tissue engineering, nano-vaccines, microbe targeting, and COVID-19 management.

APPLIED SURFACE SCIENCE ADVANCES (2022)

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Article Chemistry, Physical

Template-mediated self-assembly of magnetite-gold nanoparticle superstructures at the water-oil interface of AOT reverse microemulsions

Rebeca Fortes Martin et al.

Summary: In this study, bimetallic magnetite-gold nanostructures were synthesized using microemulsions, with different types of nanoparticles modulating the morphology and surfactant film properties. Phase separation into Winsor phases allowed the formation of micrometer-scale bimetallic heterostructures upon solvent evaporation.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2021)

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Article Chemistry, Inorganic & Nuclear

Recent development for biomedical applications of magnetic nanoparticles

Atta Ullah Khan et al.

Summary: Engineered nanoparticles, especially magnetic nanoparticles, have been increasingly utilized in various sectors such as biomedicine and environmental remediation. Recent studies have shown that magnetic nanoparticles exhibit excellent antiviral activity, including against SARS-CoV-2 (Covid-19), indicating their potential in combating viral infections.

INORGANIC CHEMISTRY COMMUNICATIONS (2021)

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Article Materials Science, Multidisciplinary

The key role of reaction temperature on a polyol synthesis of water-dispersible iron oxide nanoparticles

Pohlee Cheah et al.

Summary: This study investigates the effect of reaction temperature on the continuous growth of water-dispersible iron oxide nanoparticles in diethylene glycol. It was found that at temperatures below 235 degrees C, the nanoparticles increase in size with temperature and exhibit good water dispersibility, but at 245 degrees C precipitates are produced, making the nanoparticles unstable in an aqueous solution. X-ray Photoelectron Spectroscopy analysis was used to study surface changes at different temperatures, and various characterization techniques were employed to analyze the size, crystal structure, and magnetic properties of the nanoparticles. The relaxivity properties of the nanoparticles suggest their potential use in magnetic resonance imaging, with properties consistent with nanoparticle size prepared at different temperatures.

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS (2021)

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Article Materials Science, Multidisciplinary

Superparamagnetic Ag-Fe3O4 composites nanoparticles for magnetic fluid hyperthermia

A. Hajalilou et al.

Summary: The study explored the potential of Ag-Fe3O4 composite nanoparticles and their ferrofluids for hyperthermia applications, revealing their high potential for destroying malignant tumor cells through synthesis, characterization, and evaluation of heating performance.

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS (2021)

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Review Pharmacology & Pharmacy

An overview on nanoparticles used in biomedicine and their cytotoxicity

Mohammad Nikzamir et al.

Summary: Nanotechnology involves developing engineered nanoparticles for biomedical applications, which have unique physicochemical properties but can exhibit cytotoxicity causing concerns for clinical applications. To be successful in biomedical applications, nanoparticles must be non-toxic and biocompatible, as their small size allows them to easily enter the body and potentially reach sensitive organs. The cytotoxicity of nanoparticles depends on various factors such as size, shape, charge, chemistry, and modifications, with the main mechanism being the generation of reactive oxygen species leading to oxidative stress and cell damage. Various commonly used nanoparticles in biomedicine, including carbon-based nanoparticles, metallic nanoparticles, and quantum dots, are discussed along with their possible cytotoxicity mechanisms.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2021)

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Article Materials Science, Biomaterials

Field-controlled magnetoelectric core-shell CoFe2O4@BaTiO3 nanoparticles as effective drug carriers and drug release in vitro

Khuram Shahzad et al.

Summary: The synthesized core-shell cobalt ferrite@barium titanate (CFO@BTO) nanoparticles were successfully functionalized with anticancer drugs and showed excellent targeting effects on tumor cells in the presence of an external magnetic field. In vitro studies confirmed the magneto-electric properties of the nanoparticles and their enhanced cytotoxicity compared to free drugs under magnetic field.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

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Article Chemistry, Analytical

Study of the Catalytic Activity of the Compounds Hydrotalcite Type Treated by Microwave in the Self-Condensation of Acetone

Jamal Houssaini et al.

Summary: The self-condensation reaction of acetone to produce diacetone alcohol is of great industrial importance. By synthesizing Mg-Al based hydrotalcites using different methods and characterizing the catalysts, it was found that microwave treatment significantly improved the catalytic activity, leading to higher conversion of acetone to diacetone alcohol.

INTERNATIONAL JOURNAL OF ANALYTICAL CHEMISTRY (2021)

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Article Materials Science, Multidisciplinary

Mossbauer and MCD spectroscopy of the Fe3S4 nanoparticles synthesized by the thermal decomposition method with two different surfactants

Ruslan D. Ivantsov et al.

Summary: Greigite nanoparticles were synthesized using thermal decomposition method with oleylamine or 1-hexadecylamine as surfactants. The synthesized NPs exhibited Fe3S4 nanocrystal structure with minor inclusions of Fe9S11 phase, and were found to have OLA or HDA shells covering the magnetic core. Mo?ssbauer spectra revealed deviations in iron ions distribution among crystal positions, leading to significant changes in the magnetic circular dichroism spectra.

CURRENT APPLIED PHYSICS (2021)

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Article Materials Science, Multidisciplinary

Sonochemical route for mesoporous silica-coated magnetic nanoparticles towards pH-triggered drug delivery system

Jesus Antonio Fuentes-Garcia et al.

Summary: This study presents a pH-triggered drug release system based on magnetic nanoparticles, showing different drug release ratios under various pH conditions. Experimental results indicate that the released DOX is highly dependent on pH values, with up to 80% release at pH 5.5. These findings suggest the potential application of the system in targeted drug delivery.

JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T (2021)

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Article Chemistry, Physical

Polyol mediated synthesis of hexagonal manganese cobaltate nanoparticles for voltammetric determination of thioridazine

Chelliah Koventhan et al.

Summary: A polyol mediated synthesis method was used to successfully synthesize hexagonal manganese cobaltate nanoparticles, with the structural, morphological, and electrocatalytic performance studied. The as-prepared nanoparticles showed good performance in thioridazine oxidation, with excellent stability and selectivity demonstrated in the presence of metal ions and organic compounds.

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS (2021)

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Proceedings Paper Materials Science, Multidisciplinary

Effect of zinc oxide and alumina nanoparticles on Structural, magnetic and mechanical properties of the iron matrix synthesized by mechanical milling and thermal spraying

Abderrahmane Younes et al.

Summary: The study aimed to investigate the effects of Al2O3 and ZnO on the microstructure, magnetic, and mechanical properties of iron. Nanocomposite powders of Fe/Al2O3 and Fe/ZnO were prepared through different milling times, showing changes in crystallite size, lattice strain, coercivity, and saturation magnetization. Thermal spraying process revealed various phases in the coatings, with different magnetic behaviors observed based on the chemical composition, highlighting Fe-60(ZnO)(40) as having the highest saturation magnetization and Fe-60(Al2O3)(40) exhibiting the highest coercivity.

MATERIALS TODAY-PROCEEDINGS (2021)

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Article Chemistry, Multidisciplinary

Synthesis and characterization of magnetite nano particles with high selectivity using in-situ precipitation method

Harith Rashid et al.

SEPARATION SCIENCE AND TECHNOLOGY (2020)

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Article Materials Science, Ceramics

Synthesis and magnetic interaction on concentrated Fe3O4 nanoparticles obtained by the co-precipitation and hydrothermal chemical methods

A. C. B. Jesus et al.

CERAMICS INTERNATIONAL (2020)

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Study on synthesis and magnetic properties of Nd2Fe14B nanoparticles prepared by hydrothermal method

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JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS (2020)

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Temperature-dependent magnetic properties of magnetite nanoparticles synthesized via coprecipitation method

Innocent Nkurikiyimfura et al.

JOURNAL OF ALLOYS AND COMPOUNDS (2020)

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S. Castro-Lopes et al.

SOLID STATE SCIENCES (2020)

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Article Chemistry, Physical

Colloidal polymer-coated Zn-doped iron oxide nanoparticles with high relaxivity and specific absorption rate for efficient magnetic resonance imaging and magnetic hyperthermia

Pradip Das et al.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2020)

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Article Materials Science, Multidisciplinary

Mn-Zn ferrite nanoparticles coated with mesoporous silica as core material for heat-triggered release of therapeutic agents

Janja Stergar et al.

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS (2019)

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Review Nanoscience & Nanotechnology

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NANOSCALE RESEARCH LETTERS (2019)

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Article Nanoscience & Nanotechnology

Magnetic properties of biofunctionalized iron oxide nanoparticles as magnetic resonance imaging contrast agents

Natalia E. Gervits et al.

BEILSTEIN JOURNAL OF NANOTECHNOLOGY (2019)

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Article Chemistry, Physical

The Effect of Polyol Composition on the Structural and Magnetic Properties of Magnetite Nanoparticles for Magnetic Particle Hyperthermia

Anastasios Kotoulas et al.

MATERIALS (2019)

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Review Chemistry, Multidisciplinary

NiCu magnetic nanoparticles: review of synthesis methods, surface functionalization approaches, and biomedical applications

Irena Ban et al.

NANOTECHNOLOGY REVIEWS (2018)

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Review Materials Science, Biomaterials

Synthesis of magnetic nanoparticles and their dispersions with special reference to applications in biomedicine and biotechnology

R. V. Mehta

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2017)

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Review Engineering, Chemical

Magnetic nanoparticles for environmental and biomedical applications: A review

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Superparamagnetic Iron Oxide (Fe3O4) Nanoparticles Coated with PEG/PEI for Biomedical Applications: A Facile and Scalable Preparation Route Based on the Cathodic Electrochemical Deposition Method

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Water dispersible oleic acid-coated Fe3O4 nanoparticles for biomedical applications

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Monodispersed water-soluble maghemite nanoparticles stabilized by a polymerized bilayer of 10-undecenoic acid

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Rapid hydrothermal synthesis of magnetic CoxNi1-xFe2O4 nanoparticles and their application on removal of Congo red

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Synthesis and characterization of Mg1+xFe2-2xTixO4 nanoparticles with an adjustable Curie point

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Magnetic Nanoparticles: Surface Effects and Properties Related to Biomedicine Applications

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The synthesis and characterization of copper-nickel alloy nanoparticles with a therapeutic Curie point using the microemulsion method

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Nanoparticles as drug delivery systems

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Synthesis of copper-nickel nanoparticles prepared by mechanical milling for use in magnetic hyperthermia

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Microwave-hydrothermal synthesis of γ-Fe2O3 nanoparticles and their magnetic properties

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Local radiofrequency-induced hyperthermia using CuNi nanoparticles with therapeutically suitable Curie temperature

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Preparation and magnetic properties of magnetite nanoparticles by sol-gel method

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Maghemite nanoparticles with very high AC-losses for application in RF-magnetic hyperthermia

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Receptor-mediated targeting of magnetic nanoparticles using insulin as a surface ligand to prevent endocytosis

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Functionalisation of magnetic nanoparticles for applications in biomedicine

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