4.6 Article

CTRP3 attenuates inflammation, oxidative and cell death in cisplatin induced HK-2 cells

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Medicine, Research & Experimental

CTRP3 protects against uric acid-induced endothelial injury by inhibiting inflammation and oxidase stress in rats

Junxia Zhang et al.

Summary: The study demonstrates that CTRP3 has a protective effect against endothelial damage induced by hyperuricemia in both animal models and HUVECs, by reducing TLR4-mediated inflammation and oxidative stress, improving vascular endothelial morphology, and decreasing cell apoptosis.

EXPERIMENTAL BIOLOGY AND MEDICINE (2022)

Article Immunology

CTRP3 alleviates myocardial ischemia/reperfusion injury in mice through activating LAMP1/JIP2/JNK pathway

Yanbin Song et al.

Summary: In this study, the researchers found that CTRP3 was downregulated in patients with acute coronary syndrome (ACS) and mice with myocardial ischemia reperfusion (I/R) injury. Overexpression of CTRP3 improved cardiac function and attenuated myocardial injury caused by I/R. The protective effects of CTRP3 were mediated through the activation of the LAMP1/JIP2/JNK pathway, resulting in improved left ventricular function, decreased myocardial infarction, and reduced myocardial apoptosis.

INTERNATIONAL IMMUNOPHARMACOLOGY (2022)

Article Biochemistry & Molecular Biology

C1q/tumour necrosis factor-related protein-3 alleviates high-glucose-induced lipid accumulation and necroinflammation in renal tubular cells by activating the adenosine monophosphate-activated protein kinase pathway

Chunyang Du et al.

Summary: CTRP3 plays a role in lipid metabolism and necroinflammation in renal tubular cells by inhibiting SREBP-1 expression, increasing PPAR-α and ABCA1 expression, and inhibiting NLRP3-mediated inflammation and MLKL-dependent necroinflammation. It also activates the AMPK pathway to provide protection.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2022)

Review Chemistry, Multidisciplinary

Natural products: potential treatments for cisplatin-induced nephrotoxicity

Chun-yan Fang et al.

Summary: Cisplatin is a clinically advanced anticancer drug, but its severe nephrotoxic effects limit its clinical use. There are currently no effective drugs for cisplatin-induced kidney injury, but natural products may have potential therapeutic effects.

ACTA PHARMACOLOGICA SINICA (2021)

Article Toxicology

CTRP3 protects hippocampal neurons from oxygen-glucose deprivation-induced injury through the AMPK/Nrf2/ARE pathway

H. Ding et al.

Summary: CTRP3 exerts neuroprotective effect on OGD/R-induced cerebral injury through the regulation of the AMPK/Nrf2/ARE pathway.

HUMAN & EXPERIMENTAL TOXICOLOGY (2021)

Review Oncology

Mechanisms of Cisplatin-Induced Acute Kidney Injury: Pathological Mechanisms, Pharmacological Interventions, and Genetic Mitigations

Kristen Renee McSweeney et al.

Summary: This article summarizes the characteristics of nephrotoxicity in cisplatin treatment, the pathophysiological mechanisms of kidney injury, and the current research on pharmacological treatment options to reduce AKI. Despite years of research, interventions, and clinical trials, there is still a lack of consistent pharmacological treatment options for cisplatin-induced acute kidney injury.

CANCERS (2021)

Article Medicine, Research & Experimental

CTRP3 induces an intermediate switch of CD14++CD16+ monocyte subset with anti-inflammatory phenotype

Hongtao Zhu et al.

EXPERIMENTAL AND THERAPEUTIC MEDICINE (2020)

Article Medicine, Research & Experimental

The role of toll-like receptors in multifactorial mechanisms of early and late renal allotransplant injury, with a focus on the TLR4 receptor and mononuclear cells

Slawomir Cezary Zmonarski et al.

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE (2019)

Review Biochemistry & Molecular Biology

Recent Advances in Models, Mechanisms, Biomarkers, and Interventions in Cisplatin-Induced Acute Kidney Injury

Sara J. Holditch et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Biotechnology & Applied Microbiology

CTRP3 inhibits high glucose-induced oxidative stress and apoptosis in retinal pigment epithelial cells

Jian Zhang et al.

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY (2019)

Article Biochemistry & Molecular Biology

CTRP3 inhibits high glucose-induced human glomerular mesangial cell dysfunction

Tian-ying Hu et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2019)

Review Urology & Nephrology

Cisplatin nephrotoxicity: a review of the literature

Sandhya Manohar et al.

JOURNAL OF NEPHROLOGY (2018)

Article Biochemistry & Molecular Biology

Prdx1 alleviates cardiomyocyte apoptosis through ROS-activated MAPK pathway during myocardial ischemia/reperfusion injury

Wanwan Guo et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

Review Toxicology

DNA damage response in cisplatin-induced nephrotoxicity

Shiyao Zhu et al.

ARCHIVES OF TOXICOLOGY (2015)

Review Biochemistry & Molecular Biology

Natural product-derived pharmacological modulators of Nrf2/ARE pathway for chronic diseases

Hemant Kumar et al.

NATURAL PRODUCT REPORTS (2014)

Review Biotechnology & Applied Microbiology

Pathophysiology of Cisplatin-Induced Acute Kidney Injury

Abdullah Ozkok et al.

BIOMED RESEARCH INTERNATIONAL (2014)

Review Urology & Nephrology

Role of Nrf2 in protection against acute kidney injury

Luke M. Shelton et al.

KIDNEY INTERNATIONAL (2013)

Editorial Material Urology & Nephrology

Yes, AKI Truly Leads to CKD

Chi-yuan Hsu

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2012)

Article Biochemistry & Molecular Biology

C1q/TNF-related Protein-3 (CTRP3), a Novel Adipokine That Regulates Hepatic Glucose Output

Jonathan M. Peterson et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Urology & Nephrology

Genistein protects the kidney from cisplatin-induced injury

Mi Jeong Sung et al.

KIDNEY INTERNATIONAL (2008)

Review Urology & Nephrology

Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies

N. Pabla et al.

KIDNEY INTERNATIONAL (2008)

Review Medicine, General & Internal

Cisplatin nephrotoxicity: A review

Xin Yao et al.

AMERICAN JOURNAL OF THE MEDICAL SCIENCES (2007)

Article Biochemistry & Molecular Biology

Genomic organization, chromosomal localization and adipocytic expression of the murine gene for CORS-26 (collagenous repeat-containing sequence of 26 kDa protein)

A Schäffler et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION (2003)