期刊
NANOTECHNOLOGY
卷 27, 期 10, 页码 -出版社
IOP PUBLISHING LTD
DOI: 10.1088/0957-4484/27/10/105703
关键词
micelles; targeted imaging; cancer; folate
资金
- National Natural Science Foundation of China [21506161, 31270019]
- 973 program [2011CB933100, 2011CB932402]
- Guangdong Natural Science Funds for Distinguished Young Scholars [2014A030306036]
- Key Laboratory of Biomedical Materials in Tianjin
In this study, fluoridated hydroxyapatite: Eu3+ nanorod-loaded folate-conjugated TPGS micelles were prepared by thin-film hydration. The findings in this study demonstrate that micelles show improved dispersion, high stability, and excellent fluorescent property in aqueous solutions, suitable for targeted imaging of cancer cells with over-expressing folate receptors on their surface. The micelles designed in this study will be a promising tool for early detection of cancer.
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