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CIRCULATION (2017)
Engineering Cardiac Muscle Tissue A Maturating Field of Research
Florian Weinberger et al.
CIRCULATION RESEARCH (2017)
Human iPSC-derived myocardium-on-chip with capillary-like flow for personalized medicine
Bradley W. Ellis et al.
BIOMICROFLUIDICS (2017)
Aptamer-Based Microfluidic Electrochemical Biosensor for Monitoring Cell-Secreted Trace Cardiac Biomarkers
Su Ryon Shin et al.
ANALYTICAL CHEMISTRY (2016)
The sympathetic innervation of the heart: Important new insights
J. H. Coote et al.
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL (2016)
Human iPS cell model of type 3 long QT syndrome recapitulates drug-based phenotype correction
Daniela Malan et al.
BASIC RESEARCH IN CARDIOLOGY (2016)
Bioprinting 3D microfibrous scaffolds for engineering endothelialized myocardium and heart-on-a-chip
Yu Shrike Zhang et al.
BIOMATERIALS (2016)
Mechanical Stress Conditioning and Electrical Stimulation Promote Contractility and Force Maturation of Induced Pluripotent Stem Cell-Derived Human Cardiac Tissue
Jia-Ling Ruan et al.
CIRCULATION (2016)
A device for co-culturing autonomic neurons and cardiomyocytes using micro-fabrication techniques
Kosuke Oiwa et al.
INTEGRATIVE BIOLOGY (2016)
Sample-specific adaption of an improved electro-mechanical model of in vitro cardiac tissue
Ralf Frotscher et al.
JOURNAL OF BIOMECHANICS (2016)
Compartmentalized Microfluidic Platforms: The Unrivaled Breakthrough of In Vitro Tools for Neurobiological Research
Estrela Neto et al.
JOURNAL OF NEUROSCIENCE (2016)
Molecular and cellular neurocardiology: development, and cellular and molecular adaptations to heart disease
Beth A. Habecker et al.
JOURNAL OF PHYSIOLOGY-LONDON (2016)
Implementing oxygen control in chip-based cell and tissue culture systems
Pieter E. Oomen et al.
LAB ON A CHIP (2016)
Optical Projection Tomography Technique for Image Texture and Mass Transport Studies in Hydrogels Based on Gellan Gum
Ana M. Soto et al.
LANGMUIR (2016)
In Vitro Reconstruction of Neuronal Networks Derived from Human iPS Cells Using Microfabricated Devices
Yuzo Takayama et al.
PLOS ONE (2016)
The Comprehensive in Vitro Proarrhythmia Assay (CiPA) initiative Update on progress
Thomas Colatsky et al.
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS (2016)
Designing hydrogels for controlled drug delivery
Jianyu Li et al.
NATURE REVIEWS MATERIALS (2016)
Multi-Organ toxicity demonstration in a functional human in vitro system composed of four organs
Carlota Oleaga et al.
SCIENTIFIC REPORTS (2016)
Human Vascular Microphysiological System for in vitro Drug Screening
C. E. Fernandez et al.
SCIENTIFIC REPORTS (2016)
The myocardial regenerative potential of three-dimensional engineered cardiac tissues composed of multiple human iPS cell-derived cardiovascular cell lineages
Hidetoshi Masumoto et al.
SCIENTIFIC REPORTS (2016)
Luminescent sensing and imaging of oxygen: Fierce competition to the Clark electrode
Otto S. Wolfbeis
BIOESSAYS (2015)
Human induced pluripotent stem cell-derived versus adult cardiomyocytes: an in silico electrophysiological study on effects of ionic current block
M. Paci et al.
BRITISH JOURNAL OF PHARMACOLOGY (2015)
Matrigel Mattress A Method for the Generation of Single Contracting Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Tromondae K. Feaster et al.
CIRCULATION RESEARCH (2015)
Cardiac endothelium-myocyte interaction: clinical opportunities for new heart failure therapies regardless of ejection fraction
Shir Lynn Lim et al.
EUROPEAN HEART JOURNAL (2015)
Fluorescent protein biosensors applied to microphysiological systems
Nina Senutovitch et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2015)
Mechanism of automaticity in cardiomyocytes derived from human induced pluripotent stem cells
Jong J. Kim et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2015)
Stem cell derived in vivo-like human cardiac bodies in a microfluidic device for toxicity testing by beating frequency imaging
Gunnar Bergstrom et al.
LAB ON A CHIP (2015)
Contractility of single cardiomyocytes differentiated from pluripotent stem cells depends on physiological shape and substrate stiffness
Alexandre J. S. Ribeiro et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
A capillary-endothelium-mimetic microfluidic chip for the study of immune responses
Wen-Hao Wu et al.
SENSORS AND ACTUATORS B-CHEMICAL (2015)
Automated Video-Based Analysis of Contractility and Calcium Flux in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultured over Different Spatial Scales
Nathaniel Huebsch et al.
TISSUE ENGINEERING PART C-METHODS (2015)
Monitoring Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes with Genetically Encoded Calcium and Voltage Fluorescent Reporters
Rami Shinnawi et al.
STEM CELL REPORTS (2015)
The Autonomic Nervous System and Cardiovascular Health and Disease A Complex Balancing Act
C. Noel Bairey Merz et al.
JACC-HEART FAILURE (2015)
Human iPSC-based Cardiac Microphysiological System For Drug Screening Applications
Anurag Mathur et al.
SCIENTIFIC REPORTS (2015)
Ion Channels in the Heart
Daniel C. Bartos et al.
COMPREHENSIVE PHYSIOLOGY (2015)
Simulation of Cardiac Cell-Seeded Membranes Using the Edge-Based Smoothed FEM
Ralf Frotscher et al.
SHELL AND MEMBRANE THEORIES IN MECHANICS AND BIOLOGY: FROM MACRO- TO NANOSCALE STRUCTURES (2015)
Mechanotransduction in the Endothelium: Role of Membrane Proteins and Reactive Oxygen Species in Sensing, Transduction, and Transmission of the Signal with Altered Blood Flow
Shampa Chatterjee et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Video image-based analysis of single human induced pluripotent stem cell derived cardiomyocyte beating dynamics using digital image correlation
Antti Ahola et al.
BIOMEDICAL ENGINEERING ONLINE (2014)
Optical methods for sensing and imaging oxygen: materials, spectroscopies and applications
Xu-dong Wang et al.
CHEMICAL SOCIETY REVIEWS (2014)
Novel in vitro cardiovascular constructs composed of vascular-like networks and cardiomyocytes
Hanna Vuorenpaa et al.
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL (2014)
Dynamic cell-cell and cell-ECM interactions in the heart
Catherine M. Howard et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2014)
Functional improvement and maturation of rat and human engineered heart tissue by chronic electrical stimulation
Marc N. Hirt et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2014)
The Concordance between Nonclinical and Phase I Clinical Cardiovascular Assessment from a Cross-Company Data Sharing Initiative
Lorna Ewart et al.
TOXICOLOGICAL SCIENCES (2014)
Simultaneous mapping of membrane voltage and calcium in zebrafish heart in vivo reveals chamber-specific developmental transitions in ionic currents
Jennifer H. Hou et al.
FRONTIERS IN PHYSIOLOGY (2014)
Rapid Cellular Phenotyping of Human Pluripotent Stem Cell-Derived Cardiomyocytes using a Genetically Encoded Fluorescent Voltage Sensor
Jordan S. Leyton-Mange et al.
STEM CELL REPORTS (2014)
Computational Models of Ventricular- and Atrial-Like Human Induced Pluripotent Stem Cell Derived Cardiomyocytes
Michelangelo Paci et al.
ANNALS OF BIOMEDICAL ENGINEERING (2013)
Three-dimensional neuron-muscle constructs with neuromuscular junctions
Yuya Morimoto et al.
BIOMATERIALS (2013)
Distinct Metabolic Flow Enables Large-Scale Purification of Mouse and Human Pluripotent Stem Cell-Derived Cardiomyocytes
Shugo Tohyama et al.
CELL STEM CELL (2013)
Engineering of functional, perfusable 3D microvascular networks on a chip
Sudong Kim et al.
LAB ON A CHIP (2013)
Biowire: a platform for maturation of human pluripotent stem cell-derived cardiomyocytes
Sara S. Nunes et al.
NATURE METHODS (2013)
Myofibroblast-mediated mechanisms of pathological remodelling of the heart
Karl T. Weber et al.
NATURE REVIEWS CARDIOLOGY (2013)
Cardiomyocyte MEA Data Analysis (CardioMDA) - A Novel Field Potential Data Analysis Software for Pluripotent Stem Cell Derived Cardiomyocytes
Paruthi Pradhapan et al.
PLOS ONE (2013)
Cross talk between cardiac myocytes and fibroblasts: from multiscale investigative approaches to mechanisms and functional consequences
P. Zhang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2012)
Inflammatory mimetic microfluidic chip by immobilization of cell adhesion molecules for T cell adhesion
Sung Kyu Kim et al.
ANALYST (2012)
Adipose Stromal Cell Tubule Network Model Provides a Versatile Tool for Vascular Research and Tissue Engineering
Jertta-Riina Sarkanen et al.
CELLS TISSUES ORGANS (2012)
Three-Dimensional Architecture of Cardiomyocytes and Connective Tissues in Hypertrophic Cardiomyopathy A Scanning Electron Microscopic Observation
Yumiko Kanzaki et al.
CIRCULATION (2012)
Development, Maturation, and Transdifferentiation of Cardiac Sympathetic Nerves
Kensuke Kimura et al.
CIRCULATION RESEARCH (2012)
Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture
Anna L. Lahti et al.
DISEASE MODELS & MECHANISMS (2012)
Intracellular Energetic Units regulate metabolism in cardiac cells
Valdur Saks et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2012)
Modulation of hERG potassium channel gating normalizes action potential duration prolonged by dysfunctional KCNQ1 potassium channel
Hongkang Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Coronary vein infusion of multipotent stromal cells from bone marrow preserves cardiac function in swine ischemic cardiomyopathy via enhanced neovascularization
Takatoshi Sato et al.
LABORATORY INVESTIGATION (2011)
Impact of Sarcoplasmic Reticulum Calcium Release on Calcium Dynamics and Action Potential Morphology in Human Atrial Myocytes: A Computational Study
Jussi T. Koivumaki et al.
PLOS COMPUTATIONAL BIOLOGY (2011)
Simulation of the Undiseased Human Cardiac Ventricular Action Potential: Model Formulation and Experimental Validation
Thomas O'Hara et al.
PLOS COMPUTATIONAL BIOLOGY (2011)
Histologically Measured Cardiomyocyte Hypertrophy Correlates with Body Height as Strongly as with Body Mass Index
Richard E. Tracy et al.
CARDIOLOGY RESEARCH AND PRACTICE (2011)
A novel computational model of the human ventricular action potential and Ca transient
Eleonora Grandi et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2010)
Local Ca2+releases enable rapid heart rates in developing cardiomyocytes
Topi Korhonen et al.
JOURNAL OF PHYSIOLOGY-LONDON (2010)
Non-Cardiomyocytes Influence the Electrophysiological Maturation of Human Embryonic Stem Cell-Derived Cardiomyocytes During Differentiation
Changsung Kim et al.
STEM CELLS AND DEVELOPMENT (2010)
Cardiac Fibroblasts Regulate Myocardial Proliferation through β1 Integrin Signaling
Masaki Leda et al.
DEVELOPMENTAL CELL (2009)
Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators
Lin Tian et al.
NATURE METHODS (2009)
Physiological function and transplantation of scaffold-free and vascularized human cardiac muscle tissue
K. R. Stevens et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Quantifying the role of oxygen pressure in tissue function
David F. Wilson
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2008)
Adaptive changes in cardiac fibroblast morphology and collagen organization as a result of mechanical environment
Sarah C. Baxter et al.
CELL BIOCHEMISTRY AND BIOPHYSICS (2008)
Endothelial cell coculture within tissue-engineered cardiomyocyte sheets enhances neovascularization and improves cardiac function of ischemic hearts
Hidekazu Sekine et al.
CIRCULATION (2008)
Cell patterning: Interaction of cardiac myocytes and fibroblasts in three-dimensional culture
Troy A. Baudino et al.
MICROSCOPY AND MICROANALYSIS (2008)
Sarcomeric dysfunction in heart failure
Nazha Hamdani et al.
CARDIOVASCULAR RESEARCH (2008)
Mechanisms of disease - The failing heart - An engine out of fuel
Stefan Neubauer
NEW ENGLAND JOURNAL OF MEDICINE (2007)
Organization of β-adrenoceptor signaling compartments by sympathetic innervation of cardiac myocytes
Olga G. Shcherbakova et al.
JOURNAL OF CELL BIOLOGY (2007)
Tissue engineering of vascularized cardiac muscle from human embryonic stem cells
Oren Caspi et al.
CIRCULATION RESEARCH (2007)
VEGF receptor signalling - in control of vascular function
AK Olsson et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
Altered fibroblast function following myocardial infarction
CE Squires et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2005)
Molecular profiling of heart endothelial cells
LL Zhang et al.
CIRCULATION (2005)
Electrical interaction of mechanosensitive fibroblasts and myocytes in the heart
A Kamkin et al.
BASIC RESEARCH IN CARDIOLOGY (2005)
A model for human ventricular tissue
KHWJ ten Tusscher et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2004)
Endothelial cells promote cardiac myocyte survival and spatial reorganization - Implications for cardiac regeneration
DA Narmoneva et al.
CIRCULATION (2004)
Isolation and expansion of adult cardiac stem cells from human and murine heart
E Messina et al.
CIRCULATION RESEARCH (2004)
Adult cardiac stem cells are multipotent and support myocardial regeneration
AP Beltrami et al.
CELL (2003)
Cardiac endothelial-myocardial signaling: Its role in cardiac growth, contractile performance, and rhythmicity
DL Brutsaert
PHYSIOLOGICAL REVIEWS (2003)
Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes
I Kehat et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)