4.7 Review

Trinity of inflammation, innate immune cells and cross-talk of signalling pathways in tumour microenvironment

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Pharmacology & Pharmacy

Crosstalk relationship between adiponectin receptors, PPAR-γ and α-adrenoceptors in renal vasculature of diabetic WKYs

Sheryar Afzal et al.

Summary: This study investigated the interaction and synergistic action between adiponectin receptors and PPAR-gamma agonists in attenuating renal hemodynamics to adrenergic agonists in diabetic rats. The results showed that the combination treatment of pioglitazone and adiponectin had a significant effect on renal function recovery in diabetic rats, while the synergistic effect with irbesartan was smaller.

EUROPEAN JOURNAL OF PHARMACOLOGY (2022)

Article Environmental Sciences

Substance P and Neurokinin 1 Receptor in Chronic Inflammation and Cancer of the Head and Neck: A Review of the Literature

Francisco Esteban et al.

Summary: Head and neck cancer is a growing public health problem worldwide. Recent research has shown that substance P (SP) may play an important role in cancer through the stimulation of the neurokinin 1 receptor (NK1R) or the constitutive activation of NK1R. The current literature review focuses on the relationship between the SP/NK1R system and chronic inflammation and cancer in the head and neck region.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2022)

Article Immunology

The triumvirate of NF-ΚB, inflammation and cytokine storm in COVID-19

Ali Attiq et al.

Summary: COVID-19 highlights the importance of host immune response and immune dysregulation. Severe complications are often caused by dysregulated immune system, leading to excessive production of inflammatory mediators. Therapeutic strategies targeting NF-kappa B inhibition have shown significant effectiveness in reducing morbidity and mortality in severe COVID-19 patients.

INTERNATIONAL IMMUNOPHARMACOLOGY (2021)

Review Physiology

REGULATION AND METABOLIC FUNCTIONS OF mTORC1 AND mTORC2

Angelia Szwed et al.

Summary: Cells metabolize nutrients for growth and proliferation, with mTOR playing a key role in integrating growth and metabolism through the protein complexes mTORC1 and mTORC2. Study of mTORC1 and mTORC2 has expanded our understanding of cellular metabolism regulation and functions.

PHYSIOLOGICAL REVIEWS (2021)

Article Medicine, Research & Experimental

Antioxidant Potential of Adiponectin and Full PPAR-γ Agonist in Correcting Streptozotocin-Induced Vascular Abnormality in Spontaneously Hypertensive Rats

Sheryar Afzal et al.

Summary: Diabetic rats exhibit metabolic dysregulation and oxidative stress, but co-administration of adiponectin and PPAR-gamma agonists can improve these conditions, reducing arterial stiffness and restoring antioxidant enzyme activity levels.

PPAR RESEARCH (2021)

Article Immunology

A new prenylated benzoquinone from Cyathocalyx pruniferus abrogates LPS-induced inflammatory responses associated with PGE2, COX-2 and cytokines biosynthesis in human plasma

Ali Attiq et al.

Summary: The study isolated two new compounds with anti-inflammatory activities from Cyathocalyx pruniferus, where 2-octaprenyl-1,4-benzoquinone (5) showed potent inhibition of inflammatory mediators without cytotoxicity, indicating potential applications in acute and chronic inflammation.

INFLAMMOPHARMACOLOGY (2021)

Article Plant Sciences

Luteolin and apigenin derived glycosides from Alphonsea elliptica abrogate LPS-induced inflammatory responses in human plasma

Ali Attiq et al.

Summary: The study found that phytoconstituents from Alphonsea elliptica have potential anti-inflammatory effects against inflammatory mediators such as prostaglandin-E-2, cyclooxegenase-2, and cytokines. The isolated compounds showed significant inhibition of inflammation in human plasma without cytotoxicity.

JOURNAL OF ETHNOPHARMACOLOGY (2021)

Article Gastroenterology & Hepatology

Molecular Structure and Function of Janus Kinases: Implications for the Development of Inhibitors

Alba Garrido-Trigo et al.

JOURNAL OF CROHNS & COLITIS (2020)

Review Biochemistry & Molecular Biology

mTOR signaling pathway and mTOR inhibitors in cancer: progress and challenges

Zhilin Zou et al.

CELL AND BIOSCIENCE (2020)

Article Pharmacology & Pharmacy

NF-κB inhibitors in treatment and prevention of lung cancer

Rajan Radha Rasmi et al.

BIOMEDICINE & PHARMACOTHERAPY (2020)

Article Medicine, General & Internal

Head and neck squamous cell carcinoma

Daniel E. Johnson et al.

NATURE REVIEWS DISEASE PRIMERS (2020)

Review Oncology

Prostate carcinogenesis: inflammatory storms

Johann S. de Bono et al.

NATURE REVIEWS CANCER (2020)

Review Biotechnology & Applied Microbiology

The emerging role of epigenetic modifiers in repair of DNA damage associated with chronic inflammatory diseases

Ning Ding et al.

MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2019)

Review Immunology

Tumour-Associated Macrophages (TAMs) in Colon Cancer and How to Reeducate Them

M. A. F. Yahaya et al.

JOURNAL OF IMMUNOLOGY RESEARCH (2019)

Review Immunology

Inflammation and Cancer: Triggers, Mechanisms, and Consequences

Florian R. Greten et al.

IMMUNITY (2019)

Review Biochemistry & Molecular Biology

Dual-Specificity Phosphatases in Immunity and Infection: An Update

Roland Lang et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Review Cell Biology

Cyclooxygenase-2 in cancer: A review

Nasser Hashemi Goradel et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2019)

Review Plant Sciences

The medicinal uses, toxicities and anti-inflammatory activity of Polyalthia species (Annonaceae)

Lui Jin Yao et al.

JOURNAL OF ETHNOPHARMACOLOGY (2019)

Review Immunology

Chemokines in homeostasis and diseases

Keqiang Chen et al.

CELLULAR & MOLECULAR IMMUNOLOGY (2018)

Review Immunology

Mast cells as sources of cytokines, chemokines, and growth factors

Kaori Mukai et al.

IMMUNOLOGICAL REVIEWS (2018)

Review Oncology

PKB/Akt-dependent regulation of inflammation in cancer

Fengyuan Tang et al.

SEMINARS IN CANCER BIOLOGY (2018)

Article Multidisciplinary Sciences

IL-23 secreted by myeloid cells drives castration-resistant prostate cancer

Arianna Calcinotto et al.

NATURE (2018)

Review Pharmacology & Pharmacy

Raging the War Against Inflammation With Natural Products

Ali Attiq et al.

FRONTIERS IN PHARMACOLOGY (2018)

Article Oncology

Is Pelvic Inflammatory Disease a Risk Factor for Ovarian Cancer?

Christina B. Rasmussen et al.

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2017)

Review Immunology

Akt Signaling Pathway in Macrophage Activation and M1/M2 Polarization

Eleni Vergadi et al.

JOURNAL OF IMMUNOLOGY (2017)

Review Biochemistry & Molecular Biology

Tumor-related interleukins: old validated targets for new anti-cancer drug development

Sarra Setrerrahmane et al.

MOLECULAR CANCER (2017)

Article Biochemistry & Molecular Biology

An integrated analysis identifies STAT4 as a key regulator of ovarian cancer metastasis

L. Zhao et al.

ONCOGENE (2017)

Review Pharmacology & Pharmacy

Annonaceae: Breaking the Wall of Inflammation

Ali Attiq et al.

FRONTIERS IN PHARMACOLOGY (2017)

Article Multidisciplinary Sciences

Progressive induction of hepatocyte progenitor cells in chronically injured liver

Naoki Tanimizu et al.

SCIENTIFIC REPORTS (2017)

Article Multidisciplinary Sciences

Activin signaling is an essential component of the TGF-β induced pro-metastatic phenotype in colorectal cancer

Jonas J. Staudacher et al.

SCIENTIFIC REPORTS (2017)

Review Biochemistry & Molecular Biology

NF-kappa B signaling in inflammation

Ting Liu et al.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2017)

Article Oncology

Inflammation and Colorectal Cancer

Apple G. Long et al.

CURRENT COLORECTAL CANCER REPORTS (2017)

Review Biochemistry & Molecular Biology

Opportunities and challenges provided by crosstalk between signalling pathways in cancer

A. Prahallad et al.

ONCOGENE (2016)

Article Biochemistry & Molecular Biology

JAK-STAT signaling in cancer: From cytokines to non-coding genome

Jan Pencik et al.

CYTOKINE (2016)

Article Gastroenterology & Hepatology

Long non-coding RNA DILC regulates liver cancer stem cells via IL-6/STAT3 axis

Xue Wang et al.

JOURNAL OF HEPATOLOGY (2016)

Review Multidisciplinary Sciences

Reparative inflammation takes charge of tissue regeneration

Michael Karin et al.

NATURE (2016)

Review Biochemistry & Molecular Biology

PI3K signalling in inflammation

P. T. Hawkins et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2015)

Review Oncology

Cyclooxygenase-2 promotes tumor growth and suppresses tumor immunity

Bing Liu et al.

CANCER CELL INTERNATIONAL (2015)

Review Biochemistry & Molecular Biology

Platelet-derived growth factor (PDGF) signalling in cancer: rapidly emerging signalling landscape

Ammad Ahmad Farooqi et al.

CELL BIOCHEMISTRY AND FUNCTION (2015)

Review Oncology

The relationship between COPD and lung cancer

A. L. Durham et al.

LUNG CANCER (2015)

Review Medicine, General & Internal

Pelvic Inflammatory Disease

Robert C. Brunham et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Review Immunology

Macrophages and cancer: from mechanisms to therapeutic implications

Renato Ostuni et al.

TRENDS IN IMMUNOLOGY (2015)

Article Gastroenterology & Hepatology

Expression of COX-2 and HER-2 in colorectal cancer and their correlation

Qi-Bing Wu et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2015)

Review Biochemistry & Molecular Biology

The role of JAK-STAT signaling in adipose tissue function

Allison J. Richard et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2014)

Review Oncology

Reading between the lines; understanding drug response in the post genomic era

Constantine C. Alifrangis et al.

MOLECULAR ONCOLOGY (2014)

Article Multidisciplinary Sciences

Comprehensive molecular characterization of gastric adenocarcinoma

Adam J. Bass et al.

NATURE (2014)

Article Biochemistry & Molecular Biology

In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer

Ramona Rudalska et al.

NATURE MEDICINE (2014)

Article Multidisciplinary Sciences

Mechanism of Activation of Protein Kinase JAK2 by the Growth Hormone Receptor

Andrew J. Brooks et al.

SCIENCE (2014)

Article Oncology

Chemokines in Cancer

Melvyn T. Chow et al.

CANCER IMMUNOLOGY RESEARCH (2014)

Review Immunology

Macrophage cytokines: involvement in immunity and infectious diseases

Guillermo Arango Duque et al.

FRONTIERS IN IMMUNOLOGY (2014)

Article Oncology

Pelvic inflammatory disease and risk of invasive ovarian cancer and ovarian borderline tumors

Christina B. Rasmussen et al.

CANCER CAUSES & CONTROL (2013)

Review Oncology

Dysregulation and crosstalk of cellular signaling pathways in colon carcinogenesis

William K. K. Wu et al.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2013)

Article Oncology

Notch1-dependent regulation of p27 determines cell fate in colorectal cancer

Nevyana R. Hristova et al.

INTERNATIONAL JOURNAL OF ONCOLOGY (2013)

Review Urology & Nephrology

Inflammation and prostate carcinogenesis

Yasutomo Nakai et al.

INTERNATIONAL JOURNAL OF UROLOGY (2013)

Review Oncology

Phosphatidylinositol 3-kinase (PI3K) inhibitors as cancer therapeutics

Akintunde Akinleye et al.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2013)

Review Oncology

Tumour necrosis factor and cancer

John P. Waters et al.

JOURNAL OF PATHOLOGY (2013)

Review Biotechnology & Applied Microbiology

The Role of Epidermal Growth Factor Receptor in Cancer Metastasis and Microenvironment

Takamitsu Sasaki et al.

BIOMED RESEARCH INTERNATIONAL (2013)

Article Biochemistry & Molecular Biology

TAK1 Inhibition Promotes Apoptosis in KRAS-Dependent Colon Cancers

Anurag Singh et al.

Review Medicine, Research & Experimental

Mitogen-activated protein kinase phosphatase (MKP)-1 in immunology, physiology, and disease

Lyn M. Wancket et al.

LIFE SCIENCES (2012)

Article Multidisciplinary Sciences

Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

Ravid Straussman et al.

NATURE (2012)

Article Cell Biology

Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model

Yifeng Xia et al.

NATURE CELL BIOLOGY (2012)

Review Oncology

Prostaglandin E2 EP receptors as therapeutic targets in breast cancer

Jocelyn Reader et al.

CANCER AND METASTASIS REVIEWS (2011)

Review Biochemistry & Molecular Biology

Hallmarks of Cancer: The Next Generation

Douglas Hanahan et al.

Article Gastroenterology & Hepatology

Intestinal Inflammation and Cancer

Thomas A. Ullman et al.

GASTROENTEROLOGY (2011)

Review Immunology

Inflammation meets cancer, with NF-κB as the matchmaker

Yinon Ben-Neriah et al.

NATURE IMMUNOLOGY (2011)

Review Respiratory System

Chronic Obstructive Pulmonary Disease and Lung Cancer: New Molecular Insights

Ian M. Adcock et al.

RESPIRATION (2011)

Article Biochemistry & Molecular Biology

Roles of Peroxisome Proliferator-Activated Receptor-α and -γ in the Development of Non-Small Cell Lung Cancer

Ming-Yue Li et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2010)

Review Biochemistry & Molecular Biology

Mechanisms and functions of p38 MAPK signalling

Ana Cuadrado et al.

BIOCHEMICAL JOURNAL (2010)

Review Biochemistry & Molecular Biology

Pathological roles of MAPK signaling pathways in human diseases

Eun Kyung Kim et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)

Article Oncology

Requirement of the NF-κB Subunit p65/RelA for K-Ras-Induced Lung Tumorigenesis

Daniela S. Basseres et al.

CANCER RESEARCH (2010)

Review Biochemistry & Molecular Biology

Pattern Recognition Receptors and Inflammation

Osamu Takeuchi et al.

Review Biochemistry & Molecular Biology

Macrophage Diversity Enhances Tumor Progression and Metastasis

Bin-Zhi Qian et al.

Article Genetics & Heredity

Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements

Michael C. Haffner et al.

NATURE GENETICS (2010)

Review Oncology

Synthetic lethal approaches to breast cancer therapy

Farah L. Rehman et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2010)

Article Biotechnology & Applied Microbiology

Utilizing targeted cancer therapeutic agents in combination: novel approaches and urgent requirements

Shivanni Kummar et al.

NATURE REVIEWS DRUG DISCOVERY (2010)

Article Medicine, General & Internal

Tumor-Associated Macrophages and Survival in Classic Hodgkin's Lymphoma

Christian Steidl et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Review Cell Biology

MAPK signaling in inflammation-associated cancer development

Pengyu Huang et al.

PROTEIN & CELL (2010)

Review Pharmacology & Pharmacy

Targeting PPAR receptors in the airway for the treatment of inflammatory lung disease

Maria G. Belvisi et al.

BRITISH JOURNAL OF PHARMACOLOGY (2009)

Review Immunology

NF-kappa B Signaling Pathway, Inflammation and Colorectal Cancer

Soly Wang et al.

CELLULAR & MOLECULAR IMMUNOLOGY (2009)

Review Cell Biology

Akt-dependent and -independent mechanisms of mTOR regulation in cancer

Regan M. Memmott et al.

CELLULAR SIGNALLING (2009)

Article Respiratory System

NUCLEAR FACTOR KAPPA B INDUCTION IN AIRWAY EPITHELIUM INCREASES LUNG INFLAMMATION IN ALLERGEN-CHALLENGED MICE

James R. Sheller et al.

EXPERIMENTAL LUNG RESEARCH (2009)

Article Multidisciplinary Sciences

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

David A. Barbie et al.

NATURE (2009)

Review Multidisciplinary Sciences

The cancer genome

Michael R. Stratton et al.

NATURE (2009)

Article Cell Biology

NF-κB as a Critical Link Between Inflammation and Cancer

Michael Karin

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2009)

Review Oncology

STATs in cancer inflammation and immunity: a leading role for STAT3

Hua Yu et al.

NATURE REVIEWS CANCER (2009)

Review Oncology

Improving outcomes in patients with advanced renal cell carcinoma

Jeffrey A. Sosman

EXPERT REVIEW OF ANTICANCER THERAPY (2008)

Review Multidisciplinary Sciences

Origin and physiological roles of inflammation

Ruslan Medzhitov

NATURE (2008)

Review Multidisciplinary Sciences

Cancer-related inflammation

Alberto Mantovani et al.

NATURE (2008)

Review Oncology

Role of mitogen-activated protein kinase phosphatases (MKPs) in cancer

Gen Sheng Wu

CANCER AND METASTASIS REVIEWS (2007)

Article Oncology

Inflammation, atrophy, and prostate carcinogenesis

Angelo M. De Marzo et al.

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS (2007)

Article Multidisciplinary Sciences

Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production

Willscott E. Naugler et al.

SCIENCE (2007)

Article Oncology

Vascular endothelial growth factor and its relationship to inflammatory mediators

Laura S. Angelo et al.

CLINICAL CANCER RESEARCH (2007)

Review Biotechnology & Applied Microbiology

Strategies for optimizing combinations of molecularly targeted anticancer agents

Janet E. Dancey et al.

NATURE REVIEWS DRUG DISCOVERY (2006)

Article Multidisciplinary Sciences

IL-23 promotes tumour incidence and growth

John L. Langowski et al.

NATURE (2006)

Article Multidisciplinary Sciences

Loss of hepatic NF-κB activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation

Toshiharu Sakurai et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Rheumatology

Interleukin-6 and chronic inflammation

Cem Gabay

ARTHRITIS RESEARCH & THERAPY (2006)

Article Cell Biology

p38 MAPK in development and cancer

Cynthia Bradham et al.

CELL CYCLE (2006)

Review Biochemistry & Molecular Biology

Macrophages: Obligate partners for tumor cell migration, invasion, and metastasis

J Condeelis et al.

Review Oncology

Paradoxical roles of the immune system during cancer development

KE de Visser et al.

NATURE REVIEWS CANCER (2006)

Article Biochemistry & Molecular Biology

MAPK signalling pathways as molecular targets for anti-inflammatory therapy - from molecular mechanisms to therapeutic benefits

B Kaminska

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2005)

Article Biochemistry & Molecular Biology

AKT crystal structure and AKT-specific inhibitors

CC Kumar et al.

ONCOGENE (2005)

Article Pharmacology & Pharmacy

Role of metabolism and viruses in aflatoxin-induced liver cancer

JD Groopman et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2005)

Review Oncology

Prostate carcinogenesis and inflammation: emerging insights

GS Palapattu et al.

CARCINOGENESIS (2005)

Review Cell Biology

Opposing actions of STAT-1 and STAT-3

A Stephanou et al.

GROWTH FACTORS (2005)

Article Oncology

Regulation of anoikis by Cdc42 and Rac1

TL Cheng et al.

EXPERIMENTAL CELL RESEARCH (2004)

Review Oncology

PI3K/Akt signalling pathway and cancer

JAF Vara et al.

CANCER TREATMENT REVIEWS (2004)

Review Oncology

COX-2 inhibition and lung cancer

AB Sandler et al.

SEMINARS IN ONCOLOGY (2004)

Article Multidisciplinary Sciences

Epstein-Barr virus latent infection membrane protein 1 TRAF-binding site induces NIK/IKKα-dependent noncanonical NF-κB activation

M Luftig et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Review Biochemistry & Molecular Biology

Cancer genes and the pathways they control

B Vogelstein et al.

NATURE MEDICINE (2004)

Review Cell Biology

Prostanoids and their receptors that modulate dendritic cell-mediated immunity

N Gualde et al.

IMMUNOLOGY AND CELL BIOLOGY (2004)

Review Oncology

Cytokines in cancer pathogenesis and cancer therapy

G Dranoff

NATURE REVIEWS CANCER (2004)

Article Rheumatology

Chemokines: role in inflammation and immune surveillance

B Moser et al.

ANNALS OF THE RHEUMATIC DISEASES (2004)

Article Cell Biology

Mechanism of p38 MAP kinase activation in vivo

D Brancho et al.

GENES & DEVELOPMENT (2003)

Article Cell Biology

Prostaglandin E2 modulates dendritic cell function via EP2 and EP4 receptor subtypes

H Harizi et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2003)

Article Genetics & Heredity

Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity

DV Bulavin et al.

NATURE GENETICS (2002)

Article Biochemistry & Molecular Biology

Angiotensin II-induced transcriptional activation of the cyclin D1 gene is mediated by Egr-1 in CHO-AT1A cells

L Guillemot et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Biochemistry & Molecular Biology

Acceleration of intestinal polyposis through prostaglandin receptor EP2 in ApcΔ716 knockout mice

M Sonoshita et al.

NATURE MEDICINE (2001)

Article Biochemistry & Molecular Biology

Prostaglandin E2 increases growth and motility of colorectal carcinoma cells

HM Sheng et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Biochemistry & Molecular Biology

MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis

LM Coussens et al.

Article Pathology

Viruses, immunity, and cancer: Lessons from hepatitis B

FV Chisari

AMERICAN JOURNAL OF PATHOLOGY (2000)