相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Modulating Lysosomal pH through Innovative Multimerized Succinic Acid-Based Nucleolipid Derivatives
Benjamin Dehay et al.
BIOCONJUGATE CHEMISTRY (2023)
Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease
Jialiu Zeng et al.
NATURE COMMUNICATIONS (2023)
Defective lysosomal acidification: a new prognostic marker and therapeutic target for neurodegenerative diseases
Chih Hung Lo et al.
TRANSLATIONAL NEURODEGENERATION (2023)
Loss of ubiquitinated protein autophagy is compensated by persistent cnc/NFE2L2/Nrf2 antioxidant responses
Arindam Bhattacharjee et al.
AUTOPHAGY (2022)
Presenilin mutations and their impact on neuronal differentiation in Alzheimer's disease
Mercedes A. Hernandez-Sapiens et al.
NEURAL REGENERATION RESEARCH (2022)
Reduced mitochondria membrane potential and lysosomal acidification are associated with decreased oligomeric Aβ degradation induced by hyperglycemia: A study of mixed glia cultures
Yung-Cheng Huang et al.
PLOS ONE (2022)
Accumulation of APP-CTF induces mitophagy dysfunction in the iNSCs model of Alzheimer's disease
Seung-Eun Lee et al.
CELL DEATH DISCOVERY (2022)
Faulty autolysosome acidification in Alzheimer's disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques
Ju-Hyun Lee et al.
NATURE NEUROSCIENCE (2022)
Small molecule C381 targets the lysosome to reduce inflammation and ameliorate disease in models of neurodegeneration
Ryan T. Vest et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2022)
2022 Alzheimer's disease facts and figures
Joseph Gaugler et al.
ALZHEIMERS & DEMENTIA (2022)
Spermidine and Rapamycin Reveal Distinct Autophagy Flux Response and Cargo Receptor Clearance Profile
Sholto de Wet et al.
CELLS (2021)
Mitochondrial translation deficiency impairs NAD+-mediated lysosomal acidification
Mikako Yagi et al.
EMBO JOURNAL (2021)
Axonal generation of amyloid-β from palmitoylated APP in mitochondria-associated endoplasmic reticulum membranes
Raja Bhattacharyya et al.
CELL REPORTS (2021)
Tau and MAPT genetics in tauopathies and synucleinopathies
Etienne Leveille et al.
PARKINSONISM & RELATED DISORDERS (2021)
Quality Control in Neurons: Mitophagy and Other Selective Autophagy Mechanisms
Chantell S. Evans et al.
JOURNAL OF MOLECULAR BIOLOGY (2020)
Resveratrol Activates Neuronal Autophagy Through AMPK in the Ischemic Brain
Narayana Pineda-Ramirez et al.
MOLECULAR NEUROBIOLOGY (2020)
Autophagy and Ubiquitin-Proteasome System Coordinate to Regulate the Protein Quality Control of Neurodegenerative Disease-Associated DCTN1
Nana Wang et al.
NEUROTOXICITY RESEARCH (2020)
Autophagic Degradation of NBR1 Restricts Metastatic Outgrowth during Mammary Tumor Progression
Timothy Marsh et al.
DEVELOPMENTAL CELL (2020)
ROCK inhibitors upregulate the neuroprotective Parkin-mediated mitophagy pathway
Natalia Moskal et al.
NATURE COMMUNICATIONS (2020)
Clinical trials of new drugs for Alzheimer disease
Li-Kai Huang et al.
JOURNAL OF BIOMEDICAL SCIENCE (2020)
Human tyrosine hydroxylase in Parkinson's disease and in related disorders
Toshiharu Nagatsu et al.
JOURNAL OF NEURAL TRANSMISSION (2019)
Sequential formation of different layers of dystrophic neurites in Alzheimer's brains
Md Golam Sharoar et al.
MOLECULAR PSYCHIATRY (2019)
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease
Evandro F. Fang et al.
NATURE NEUROSCIENCE (2019)
Loss of PINK1 causes age-dependent decrease of dopamine release and mitochondrial dysfunction
Lianteng Zhi et al.
NEUROBIOLOGY OF AGING (2019)
Therapeutic activation of autophagy by combined treatment with rapamycin and trehalose in a mouse MPTP-induced model of Parkinson's disease
Alexander B. Pupyshev et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2019)
LC3/GABARAPs drive ubiquitin-independent recruitment of Optineurin and NDP52 to amplify mitophagy
Benjamin Scott Padman et al.
NATURE COMMUNICATIONS (2019)
ATP6AP2 variant impairs CNS development and neuronal survival to cause fulminant neurodegeneration
Takuo Hirose et al.
JOURNAL OF CLINICAL INVESTIGATION (2019)
Depletion of NBR1 in urothelial carcinoma cells enhances rapamycin-induced apoptosis through impaired autophagy and mitochondrial dysfunction
Myeong Joo Kim et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2019)
Mitochondrial fission requires DRP1 but not dynamins
Tiago Branco Fonseca et al.
NATURE (2019)
The good, the bad and the autophagosome: exploring unanswered questions of autophagy-dependent cell death
Jurgen Kriel et al.
CELL DEATH AND DIFFERENTIATION (2019)
2019 Alzheimer's disease facts and figures
Joseph Gaugler et al.
ALZHEIMERS & DEMENTIA (2019)
Evidence for brain glucose dysregulation in Alzheimer's disease
Yang An et al.
ALZHEIMERS & DEMENTIA (2018)
Probing the correlation of neuronal loss, neurofibrillary tangles, and cell death markers across the Alzheimer's disease Braak stages: a quantitative study in humans
Panos Theofilas et al.
NEUROBIOLOGY OF AGING (2018)
Exogenous α-synuclein hinders synaptic communication in cultured cortical primary rat neurons
G. C. Hassink et al.
PLOS ONE (2018)
Resveratrol ameliorates autophagic flux to promote functional recovery in rats after spinal cord injury
Peng Wang et al.
Oncotarget (2018)
Asiatic Acid Prevents Oxidative Stress and Apoptosis by Inhibiting the Translocation of α-Synuclein Into Mitochondria
Hongqun Ding et al.
FRONTIERS IN NEUROSCIENCE (2018)
The Precision Control of Autophagic Flux and Vesicle Dynamics-A Micropattern Approach
Andre du Toit et al.
CELLS (2018)
Validating the RedMIT/GFP-LC3 Mouse Model by Studying Mitophagy in Autosomal Dominant Optic Atrophy Due to the OPA1Q285STOP Mutation
Alan Diot et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2018)
被撤回的出版物: p62 improves AD-like pathology by increasing autophagy (Retracted article. See vol. 26, pg. 3664, 2021)
A. Caccamo et al.
MOLECULAR PSYCHIATRY (2017)
Mitochondrial fission facilitates the selective mitophagy of protein aggregates
Jonathon L. Burman et al.
JOURNAL OF CELL BIOLOGY (2017)
Parkin deficiency accelerates consequences of mitochondrial DNA deletions and Parkinsonism
Lanying Song et al.
NEUROBIOLOGY OF DISEASE (2017)
Autophagic flux control in neurodegeneration: Progress and precision targeting-Where do we stand?
Dumisile Lumkwana et al.
PROGRESS IN NEUROBIOLOGY (2017)
Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson's disease
Lena F. Burbulla et al.
SCIENCE (2017)
Rapamycin upregulates glutamate transporter and IL-6 expression in astrocytes in a mouse model of Parkinson's disease
Yunlong Zhang et al.
CELL DEATH & DISEASE (2017)
Promoting Drp1-mediated mitochondrial fission in midlife prolongs healthy lifespan of Drosophila melanogaster
Anil Rana et al.
NATURE COMMUNICATIONS (2017)
AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species
Rebecca C. Rabinovitch et al.
CELL REPORTS (2017)
Mitophagy Failure in Fibroblasts and iPSC-Derived Neurons of Alzheimer's Disease-Associated Presenilin 1 Mutation
Patricia Martin-Maestro et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2017)
Protein misfolding in neurodegenerative diseases: implications and strategies
Patrick Sweeney et al.
TRANSLATIONAL NEURODEGENERATION (2017)
p62 Pathology Model in the Rat Substantia Nigra with Filamentous Inclusions and Progressive Neurodegeneration
Kasey L. Jackson et al.
PLOS ONE (2017)
Pathogenic p62/SQSTM1 mutations impair energy metabolism through limitation of mitochondrial substrates
Fernando Bartolome et al.
SCIENTIFIC REPORTS (2017)
Endoplasmic reticulum proteostasis impairment in aging
Gabriela Martinez et al.
AGING CELL (2017)
Molecular definitions of autophagy and related processes
Lorenzo Galluzzi et al.
EMBO JOURNAL (2017)
Autophagy flux in CA1 neurons of Alzheimer hippocampus: Increased induction overburdens failing lysosomes to propel neuritic dystrophy
Matteo Bordi et al.
AUTOPHAGY (2016)
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Daniel J. Klionsky et al.
AUTOPHAGY (2016)
Repetitive mild traumatic brain injury with impact acceleration in the mouse: Multifocal axonopathy, neuroinflammation, and neurodegeneration in the visual system
Leyan Xu et al.
EXPERIMENTAL NEUROLOGY (2016)
The clinical symptoms of Parkinson's disease
Sigurlaug Sveinbjornsdottir
JOURNAL OF NEUROCHEMISTRY (2016)
Mitochondrial dysfunction in Parkinson's disease
Anindita Bose et al.
JOURNAL OF NEUROCHEMISTRY (2016)
An Autophagic Flux Probe that Releases an Internal Control
Takeshi Kaizuka et al.
MOLECULAR CELL (2016)
α-Synuclein binds to TOM20 and inhibits mitochondrial protein import in Parkinson's disease
Roberto Di Maio et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
Toxicant Exposure and Bioaccumulation: A Common and Potentially Reversible Cause of Cognitive Dysfunction and Dementia
Stephen J. Genuis et al.
BEHAVIOURAL NEUROLOGY (2015)
Early maturation and distinct tau pathology in induced pluripotent stem cell-derived neurons from patients with MAPT mutations
Mariangela Iovino et al.
BRAIN (2015)
Lack of Neuronal IFN-β-IFNAR Causes Lewy Body- and Parkinson's Disease-like Dementia
Patrick Ejlerskov et al.
CELL (2015)
Autophagy and proteins involved in vesicular trafficking
Celina Amaya et al.
FEBS LETTERS (2015)
Conditional depletion of intellectual disability and Parkinsonism candidate geneATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration
Aline Dubos et al.
HUMAN MOLECULAR GENETICS (2015)
On the translocation of bacteria and their lipopolysaccharides between blood and peripheral locations in chronic, inflammatory diseases: the central roles of LPS and LPS-induced cell death
Douglas B. Kell et al.
INTEGRATIVE BIOLOGY (2015)
VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for α-Synuclein Degradation and Prevention of Pathogenesis of Parkinson's Disease
Fu-Lei Tang et al.
JOURNAL OF NEUROSCIENCE (2015)
Proteostasis and aging
Susmita Kaushik et al.
NATURE MEDICINE (2015)
Compromised autophagy and neurodegenerative diseases
Fiona M. Menzies et al.
NATURE REVIEWS NEUROSCIENCE (2015)
Aβ(1-42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease
Yiling Xiao et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
ROTENONE IMPAIRS AUTOPHAGIC FLUX AND LYSOSOMAL FUNCTIONS IN PARKINSON'S DISEASE
F. Wu et al.
NEUROSCIENCE (2015)
Aβ(1-42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease
Yiling Xiao et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Presenilin 1 Maintains Lysosomal Ca2+ Homeostasis via TRPML1 by Regulating vATPase-Mediated Lysosome Acidification
Ju-Hyun Lee et al.
CELL REPORTS (2015)
Proteotoxic Stress Induces Phosphorylation of p62/SQSTM1 by ULK1 to Regulate Selective Autophagic Clearance of Protein Aggregates
Junghyun Lim et al.
PLOS GENETICS (2015)
Spermidine induces autophagy by inhibiting the acetyltransferase EP300
F. Pietrocola et al.
CELL DEATH AND DIFFERENTIATION (2015)
Resveratrol inhibits β-amyloid-induced neuronal apoptosis via regulation of p53 acetylation in PC12 cells
Zhibing Ai et al.
MOLECULAR MEDICINE REPORTS (2015)
Inside Alzheimer brain with CLARITY: senile plaques, neurofibrillary tangles and axons in 3-D
Kunie Ando et al.
ACTA NEUROPATHOLOGICA (2014)
Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury
Chinmoy Sarkar et al.
AUTOPHAGY (2014)
Expression of the autophagy substrate SQSTM1/p62 is restored during prolonged starvation depending on transcriptional upregulation and autophagy- derived amino acids
Mayurbhai Himatbhai Sahani et al.
AUTOPHAGY (2014)
Defining and measuring autophagosome flux-concept and reality
Ben Loos et al.
AUTOPHAGY (2014)
Mitochondrial permeability transition pore is a potential drug target for neurodegeneration
Valasani Koteswara Rao et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2014)
Proteostasis and neurodegeneration: The roles of proteasomal degradation and autophagy
Keiji Tanaka et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2014)
BNIP3 Interacting with LC3 Triggers Excessive Mitophagy in Delayed Neuronal Death in Stroke
Ruo-Yang Shi et al.
CNS NEUROSCIENCE & THERAPEUTICS (2014)
Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB
Vinicia A. Polito et al.
EMBO MOLECULAR MEDICINE (2014)
Neurodegenerative disorders: Dysregulation of a carefully maintained balance?
Chrisna Swart et al.
EXPERIMENTAL GERONTOLOGY (2014)
Calcium Release from Intra-Axonal Endoplasmic Reticulum Leads to Axon Degeneration through Mitochondrial Dysfunction
Rosario Villegas et al.
JOURNAL OF NEUROSCIENCE (2014)
Cargo recognition and trafficking in selective autophagy
Alexandra Stolz et al.
NATURE CELL BIOLOGY (2014)
Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases
Claudio Hetz et al.
NATURE REVIEWS NEUROSCIENCE (2014)
Chronic blockade of extrasynaptic NMDA receptors ameliorates synaptic dysfunction and pro-death signaling in Huntington disease transgenic mice
Alejandro Dau et al.
NEUROBIOLOGY OF DISEASE (2014)
A clinical classification acknowledging neuropsychiatric and cognitive impairment in Huntington's disease
Tua Vinther-Jensen et al.
ORPHANET JOURNAL OF RARE DISEASES (2014)
Differential ubiquitination and degradation of huntingtin fragments modulated by ubiquitin-protein ligase E3A
Kavita P. Bhat et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
At the end of the autophagic road: an emerging understanding of lysosomal functions in autophagy
Han-Ming Shen et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
Chronic brain inflammation causes a reduction in GluN2A and GluN2B subunits of NMDA receptors and an increase in the phosphorylation of mitogen-activated protein kinases in the hippocampus
Jinhua Ma et al.
MOLECULAR BRAIN (2014)
Axonopathy in an α-Synuclein Transgenic Model of Lewy Body Disease Is Associated with Extensive Accumulation of C-Terminal Truncated α-Synuclein
Dora Games et al.
AMERICAN JOURNAL OF PATHOLOGY (2013)
The emerging role of acetylation in the regulation of autophagy
Agnes Banreti et al.
AUTOPHAGY (2013)
Temporal analysis of recruitment of mammalian ATG proteins to the autophagosome formation site
Ikuko Koyama-Honda et al.
AUTOPHAGY (2013)
The variability of autophagy and cell death susceptibility Unanswered questions
Ben Loos et al.
AUTOPHAGY (2013)
PINK1 is degraded through the N-end rule pathway
Koji Yamano et al.
AUTOPHAGY (2013)
Lysosome and calcium dysregulation in Alzheimer's disease: partners in crime
MaryKate McBrayer et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2013)
Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers
Sovan Sarkar
BIOCHEMICAL SOCIETY TRANSACTIONS (2013)
Genetic Insights into Sporadic Parkinson's Disease Pathogenesis
Chou Chai et al.
CURRENT GENOMICS (2013)
The role of 'eat-me' signals and autophagy cargo receptors in innate immunity
Keith B. Boyle et al.
CURRENT OPINION IN MICROBIOLOGY (2013)
A Dimeric PINK1-containing Complex on Depolarized Mitochondria Stimulates Parkin Recruitment
Kei Okatsu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Suppression of Lysosome Function Induces Autophagy via a Feedback Down-regulation of MTOR Complex 1 (MTORC1) Activity
Min Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Expanded Polyglutamine-containing N-terminal Huntingtin Fragments Are Entirely Degraded by Mammalian Proteasomes
Katrin Juenemann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Where is mTOR and what is it doing there?
Charles Betz et al.
JOURNAL OF CELL BIOLOGY (2013)
NBR1 acts as an autophagy receptor for peroxisomes
Elizabeth Deosaran et al.
JOURNAL OF CELL SCIENCE (2013)
The Lewy Body in Parkinson's Disease and Related Neurodegenerative Disorders
Koichi Wakabayashi et al.
MOLECULAR NEUROBIOLOGY (2013)
ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase
Ryan C. Russell et al.
NATURE CELL BIOLOGY (2013)
Impaired complex IV activity in response to loss of LRPPRC function can be compensated by mitochondrial hyperfusion
Stephane G. Rolland et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Aβ Secretion and Plaque Formation Depend on Autophagy
Per Nilsson et al.
CELL REPORTS (2013)
The genetics and neuropathology of Parkinson's disease
Henry Houlden et al.
ACTA NEUROPATHOLOGICA (2012)
MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB
Jose A. Martina et al.
AUTOPHAGY (2012)
Degradation of mutant huntingtin via the ubiquitin/proteasome system is modulated by FE65
Wan Ning Vanessa Chow et al.
BIOCHEMICAL JOURNAL (2012)
α-Synuclein misfolding and Parkinson's disease
Leonid Breydo et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2012)
Mitophagy is triggered by mild oxidative stress in a mitochondrial fission dependent manner
Magdalena Frank et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2012)
Phosphatidylinositol-3-Phosphate Clearance Plays a Key Role in Autophagosome Completion
Eduardo Cebollero et al.
CURRENT BIOLOGY (2012)
Role of PINK1 Binding to the TOM Complex and Alternate Intracellular Membranes in Recruitment and Activation of the E3 Ligase Parkin
Michael Lazarou et al.
DEVELOPMENTAL CELL (2012)
Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease
Ulziibat P. Shirendeb et al.
HUMAN MOLECULAR GENETICS (2012)
Up-regulation of GLT1 reverses the deficit in cortically evoked striatal ascorbate efflux in the R6/2 mouse model of Huntington's disease
Benjamin R. Miller et al.
JOURNAL OF NEUROCHEMISTRY (2012)
Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks
Sebastian Alers et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
Striatal neuronal loss correlates with clinical motor impairment in Huntington's disease
Zhihong Guo et al.
MOVEMENT DISORDERS (2012)
Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration
Rhonda M. Perciavalle et al.
NATURE CELL BIOLOGY (2012)
AMPK: a nutrient and energy sensor that maintains energy homeostasis
D. Grahame Hardie et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Dysregulated dopamine storage increases the vulnerability to α-synuclein in nigral neurons
Ayse Ulusoy et al.
NEUROBIOLOGY OF DISEASE (2012)
Mitochondria-Specific Accumulation of Amyloid β Induces Mitochondrial Dysfunction Leading to Apoptotic Cell Death
Moon-Yong Cha et al.
PLOS ONE (2012)
Analysis of Proteolytic Processes and Enzymatic Activities in the Generation of Huntingtin N-Terminal Fragments in an HEK293 Cell Model
Andrew T. N. Tebbenkamp et al.
PLOS ONE (2012)
Emerging role of p62/sequestosome-1 in the pathogenesis of Alzheimer's disease
Antero Salminen et al.
PROGRESS IN NEUROBIOLOGY (2012)
Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy
W-Y Shi et al.
CELL DEATH & DISEASE (2012)
Neurotoxicity of Amyloid β-Protein: Synaptic and Network Dysfunction
Lennart Mucke et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)
Calcium Dysregulation and Homeostasis of Neural Calcium in the Molecular Mechanisms of Neurodegenerative Diseases Provide Multiple Targets for Neuroprotection
Gregor Zuendorf et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
Sustained calcium signalling and caspase-3 activation involve NMDA receptors in thymocytes in contact with dendritic cells
P. Affaticati et al.
CELL DEATH AND DIFFERENTIATION (2011)
Mitochondrial oxidative stress causes mitochondrial fragmentation via differential modulation of mitochondrial fission-fusion proteins
Shengnan Wu et al.
FEBS JOURNAL (2011)
Transgenic mice expressing caspase-6-derived N-terminal fragments of mutant huntingtin develop neurologic abnormalities with predominant cytoplasmic inclusion pathology composed largely of a smaller proteolytic derivative
Andrew T. N. Tebbenkamp et al.
HUMAN MOLECULAR GENETICS (2011)
Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage
Ulziibat Shirendeb et al.
HUMAN MOLECULAR GENETICS (2011)
Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome
Eugenia Morselli et al.
JOURNAL OF CELL BIOLOGY (2011)
The role of alpha-synuclein in neurotransmission and synaptic plasticity
Furong Cheng et al.
JOURNAL OF CHEMICAL NEUROANATOMY (2011)
Lysosomal Proteolysis Inhibition Selectively Disrupts Axonal Transport of Degradative Organelles and Causes an Alzheimer's-Like Axonal Dystrophy
Sooyeon Lee et al.
JOURNAL OF NEUROSCIENCE (2011)
Distinct Roles In Vivo for the Ubiquitin-Proteasome System and the Autophagy-Lysosomal Pathway in the Degradation of α-Synuclein
Darius Ebrahimi-Fakhari et al.
JOURNAL OF NEUROSCIENCE (2011)
Rho GTPase regulation of α-synuclein and VMAT2: Implications for pathogenesis of Parkinson's disease
Zhigang Zhou et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2011)
Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice
Cristian A. Lasagna-Reeves et al.
MOLECULAR NEURODEGENERATION (2011)
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
Joungmok Kim et al.
NATURE CELL BIOLOGY (2011)
Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease
Marcello D'Amelio et al.
NATURE NEUROSCIENCE (2011)
Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death
Laura A. Volpicelli-Daley et al.
NEURON (2011)
TFEB Links Autophagy to Lysosomal Biogenesis
Carmine Settembre et al.
SCIENCE (2011)
Neuropathological Alterations in Alzheimer Disease
Alberto Serrano-Pozo et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2011)
Soluble hyper-phosphorylated tau causes microtubule breakdown and functionally compromises normal tau in vivo
Catherine M. Cowan et al.
ACTA NEUROPATHOLOGICA (2010)
Mammalian Sirtuins: Biological Insights and Disease Relevance
Marcia C. Haigis et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2010)
Regulation of SIRT1 in cellular functions: Role of polyphenols
Sangwoon Chung et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2010)
Acetylated microtubules are required for fusion of autophagosomes with lysosomes
Rui Xie et al.
BMC CELL BIOLOGY (2010)
Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations
Ju-Hyun Lee et al.
CELL (2010)
Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids
Yasemin Sancak et al.
CELL (2010)
Mammalian autophagy: core molecular machinery and signaling regulation
Zhifen Yang et al.
CURRENT OPINION IN CELL BIOLOGY (2010)
Elevated tauopathy and alpha-synuclein pathology in postmortem Parkinson's disease brains with and without dementia
Jonathan Wills et al.
EXPERIMENTAL NEUROLOGY (2010)
Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease
Claudia Rose et al.
HUMAN MOLECULAR GENETICS (2010)
In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects
Mathilde Faideau et al.
HUMAN MOLECULAR GENETICS (2010)
Lysosomal Degradation of α-Synuclein in Vivo
Sally K. Mak et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Molecular Interplay between Mammalian Target of Rapamycin (mTOR), Amyloid-β, and Tau EFFECTS ON COGNITIVE IMPAIRMENTS
Antonella Caccamo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
Seok Min Jin et al.
JOURNAL OF CELL BIOLOGY (2010)
FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport
Serhiy Pankiv et al.
JOURNAL OF CELL BIOLOGY (2010)
Rapamycin Protects against Neuron Death in In Vitro and In Vivo Models of Parkinson's Disease
Cristina Malagelada et al.
JOURNAL OF NEUROSCIENCE (2010)
NMDA-Mediated Ca2+ Influx Drives Aberrant Ryanodine Receptor Activation in Dendrites of Young Alzheimer's Disease Mice
Ivan Goussakov et al.
JOURNAL OF NEUROSCIENCE (2010)
Nbr1 Is a Novel Inhibitor of Ligand-Mediated Receptor Tyrosine Kinase Degradation
Faraz K. Mardakheh et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
Clifford R. Jack et al.
LANCET NEUROLOGY (2010)
Termination of autophagy and reformation of lysosomes regulated by mTOR
Li Yu et al.
NATURE (2010)
Selective autophagy: ubiquitin-mediated recognition and beyond
Claudine Kraft et al.
NATURE CELL BIOLOGY (2010)
Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease
Marta Martinez-Vicente et al.
NATURE NEUROSCIENCE (2010)
Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy
Sang-Won Min et al.
NEURON (2010)
BETA AMYLOID-INDEPENDENT ROLE OF AMYLOID PRECURSOR PROTEIN IN GENERATION AND MAINTENANCE OF DENDRITIC SPINES
K. J. Lee et al.
NEUROSCIENCE (2010)
Memantine treatment decreases levels of secreted Alzheimer's amyloid precursor protein (APP) and amyloid beta (Aβ) peptide in the human neuroblastoma cells
Balmiki Ray et al.
NEUROSCIENCE LETTERS (2010)
Mitochondrial alpha-synuclein accumulation impairs complex I function in dopaminergic neurons and results in increased mitophagy in vivo
Shankar J. Chinta et al.
NEUROSCIENCE LETTERS (2010)
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
Brinda Ravikumar et al.
PHYSIOLOGICAL REVIEWS (2010)
Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-beta Levels in a Mouse Model of Alzheimer's Disease
Patricia Spilman et al.
PLOS ONE (2010)
Autophagy and Metabolism
Joshua D. Rabinowitz et al.
SCIENCE (2010)
Autophagy and innate immunity: Triggering, targeting and tuning
Rhea Sumpter et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2010)
HSP72 Protects Cells from ER Stress-induced Apoptosis via Enhancement of IRE1α-XBP1 Signaling through a Physical Interaction
Sanjeev Gupta et al.
PLOS BIOLOGY (2010)
Mendelian forms of Parkinson's disease
Thomas Gasser
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2009)
p62 at the Crossroads of Autophagy, Apoptosis, and Cancer
Jorge Moscat et al.
CELL (2009)
Role of BNIP3 and NIX in cell death, autophagy, and mitophagy
J. Zhang et al.
CELL DEATH AND DIFFERENTIATION (2009)
The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1
J. M. Vicencio et al.
CELL DEATH AND DIFFERENTIATION (2009)
Regulation of Autophagy by the p300 Acetyltransferase
In Hye Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Intranuclear Degradation of Polyglutamine Aggregates by the Ubiquitin-Proteasome System
Atsushi Iwata et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Caspase-cleaved Tau Expression Induces Mitochondrial Dysfunction in Immortalized Cortical Neurons IMPLICATIONS FOR THE PATHOGENESIS OF ALZHEIMER DISEASE
Rodrigo A. Quintanilla et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways
Jenelle M. Timmins et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease
Xinglong Wang et al.
JOURNAL OF NEUROSCIENCE (2009)
A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates
Vladimir Kirkin et al.
MOLECULAR CELL (2009)
Induction of autophagy by spermidine promotes longevity
Tobias Eisenberg et al.
NATURE CELL BIOLOGY (2009)
Amyloid formation by globular proteins under native conditions
Fabrizio Chiti et al.
NATURE CHEMICAL BIOLOGY (2009)
Amyloid-β as a positive endogenous regulator of release probability at hippocampal synapses
Efrat Abramov et al.
NATURE NEUROSCIENCE (2009)
Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin
Gerardo A. Morfini et al.
NATURE NEUROSCIENCE (2009)
Amyloid precursor protein increases cortical neuron size in transgenic mice
Esther S. Oh et al.
NEUROBIOLOGY OF AGING (2009)
Physicochemical principles that regulate the competition between functional and dysfunctional association of proteins
Sebastian Pechmann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Calcium dysregulation in Alzheimer's disease: From mechanisms to therapeutic opportunities
Jin-Tai Yu et al.
PROGRESS IN NEUROBIOLOGY (2009)
A Gene Network Regulating Lysosomal Biogenesis and Function
Marco Sardiello et al.
SCIENCE (2009)
Amyloid precursor protein knockout mice show age-dependent deficits in passive avoidance learning
Yann Senechal et al.
BEHAVIOURAL BRAIN RESEARCH (2008)
Mitochondrial association of alpha-synuclein causes oxidative stress
M. S. Parihar et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2008)
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
Gilad Twig et al.
EMBO JOURNAL (2008)
Autophagic-lysosomal perturbation enhances tau aggregation in transfectants with induced wild-type tau expression
Tadanori Hamano et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2008)
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
Elizabeth L. Axe et al.
JOURNAL OF CELL BIOLOGY (2008)
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
Derek Narendra et al.
JOURNAL OF CELL BIOLOGY (2008)
Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease
Jing-Ji Jin et al.
JOURNAL OF NEUROINFLAMMATION (2008)
N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking
Adam L. Orr et al.
JOURNAL OF NEUROSCIENCE (2008)
Autophagy induction and autophagosome clearance in neurons: Relationship to autophagic pathology in Alzheimer's disease
Barry Boland et al.
JOURNAL OF NEUROSCIENCE (2008)
Microglial dysfunction and defective β-amyloid clearance pathways in aging Alzheimer's disease mice
Suzanne E. Hickman et al.
JOURNAL OF NEUROSCIENCE (2008)
Autophagy fights disease through cellular self-digestion
Noboru Mizushima et al.
NATURE (2008)
Regulation of TORC1 by Rag GTPases in nutrient response
Eunjung Kim et al.
NATURE CELL BIOLOGY (2008)
Endocytosis is required for synaptic activity-dependent release of amyloid-β in vivo
John R. Cirrito et al.
NEURON (2008)
Stress as a neuroinflammatory condition in brain:: Damaging and protective mechanisms
Borja Garcia-Bueno et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2008)
Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis
P. Pinton et al.
ONCOGENE (2008)
Preventing Mitochondrial Fission Impairs Mitochondrial Function and Leads to Loss of Mitochondrial DNA
Philippe A. Parone et al.
PLOS ONE (2008)
Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes
Peter Kijun Kim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The amyloid β-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae
Camilla A. Hansson Petersen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1
Yasemin Sancak et al.
SCIENCE (2008)
Adapting proteostasis for disease intervention
William E. Balch et al.
SCIENCE (2008)
The itinerary of autophagosomes: From peripheral formation to kiss-and-run fusion with lysosomes
Luca Jahreiss et al.
TRAFFIC (2008)
Inhibition of vesicular monoamine transporter-2 activity in alpha-synuclein stably transfected SH-SY5Y cells
Jun Tang Guo et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2008)
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice
Masaaki Komatsu et al.
CELL (2007)
Autophagy, amyloidogenesis and Alzheimer disease
Ralph A. Nixon
JOURNAL OF CELL SCIENCE (2007)
Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology
Michoel Forgac
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
Serhiy Pankiv et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
Udai Bhan Pandey et al.
NATURE (2007)
Natural oligomers of the Alzheimer amyloid-β protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway
Ganesh M. Shankar et al.
JOURNAL OF NEUROSCIENCE (2007)
Soluble protein oligomers in neurodegeneration:: lessons from the Alzheimer's amyloid β-peptide
Christian Haass et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Polymodal regulation of NMDA receptor channels
Anna Kloda et al.
CHANNELS (2007)
ROS, mitochondria and the regulation of autophagy
Ruth Scherz-Shouval et al.
TRENDS IN CELL BIOLOGY (2007)
Age-associated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease?
Yaping Chu et al.
NEUROBIOLOGY OF DISEASE (2007)
Microtubules support production of starvation-induced autophagosomes but not their targeting and fusion with lysosomes
Ephraim Fass et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Memantine reduces striatal cell death with decreasing calpain level in 3-nitropropionic model of Huntington's disease
Soon-Tae Lee et al.
BRAIN RESEARCH (2006)
Relationship among α-synuclein accumulation, dopamine synthesis, and neurodegeneration in Parkinson disease substantia nigra
Fumiaki Mori et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2006)
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
Taichi Hara et al.
NATURE (2006)
Loss of autophagy in the central nervous system causes neurodegeneration in mice
Masaaki Komatsu et al.
NATURE (2006)
Mitochondria are a direct site of Aβ accumulation in Alzheimer's disease neurons:: implications for free radical generation and oxidative damage in disease progression
M Manczak et al.
HUMAN MOLECULAR GENETICS (2006)
Consequences of the selective blockage of chaperone-mediated autophagy
AC Massey et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
TOR signaling in growth and metabolism
S Wullschleger et al.
CELL (2006)
Rapamycin alleviates toxicity of different aggregate-prone proteins
Z Berger et al.
HUMAN MOLECULAR GENETICS (2006)
TOR signaling in growth and metabolism
Stephan Wullschleger et al.
CELL (2006)
Progression patterns of neuronal loss and Lewy body pathology in the substantia nigra in Parkinson's disease
K. Wakabayashi et al.
PARKINSONISM & RELATED DISORDERS (2006)
Episodic memory impairment in Huntington's disease: A meta-analysis
Alonso Montoya et al.
NEUROPSYCHOLOGIA (2006)
The bipyridyl herbicide paraquat produces oxidative stress-mediated toxicity in human neuroblastoma SH-SY5Y cells: Relevance to the dopaminergic pathogenesis
WS Yang et al.
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES (2005)
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
G Bjorkoy et al.
JOURNAL OF CELL BIOLOGY (2005)
Lithium induces autophagy by inhibiting inositol monophosphatase
S Sarkar et al.
JOURNAL OF CELL BIOLOGY (2005)
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
S Pattingre et al.
CELL (2005)
Increased susceptibility of cytoplasmic over nuclear polyglutamine aggregates to autophagic degradation
A Iwata et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Dynein mutations impair autophagic clearance of aggregate-prone proteins
B Ravikumar et al.
NATURE GENETICS (2005)
Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L Tau transgenic mice
DC David et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease
AJ Whitworth et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Absence of inclusion body formation in the MPTP mouse model of Parkinson's disease
M Shimoji et al.
MOLECULAR BRAIN RESEARCH (2005)
Mitochondrial dysfunction, endoplasmic reticulum stress, and apoptosis in Alzheimer's disease
K Takuma et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2005)
Inflammatory cytokine levels correlate with amyloid load in transgenic mouse models of Alzheimer's disease
Nikunj S. Patel et al.
JOURNAL OF NEUROINFLAMMATION (2005)
Extensive involvement of autophagy in Alzheimer disease: An immuno-electron microscopy study
RA Nixon et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2005)
Amyloid β peptide load is correlated with increased β-secretase activity in sporadic Alzheimer's disease patients
R Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Neurodegeneration or neuroprotection: The pivotal role of astrocytes
SJR Heales et al.
NEUROCHEMICAL RESEARCH (2004)
Mutant genes responsible for Parkinson's disease
W Le et al.
CURRENT OPINION IN PHARMACOLOGY (2004)
LC3 conjugation system in mammalian autophagy
I Tanida et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
Involvement of macroautophagy in the dissolution of neuronal inclusions
HJ Rideout et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
M Arrasate et al.
NATURE (2004)
Stages in the development of Parkinson's disease-related pathology
H Braak et al.
CELL AND TISSUE RESEARCH (2004)
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
EM Valente et al.
SCIENCE (2004)
Tuberous sclerosis complex gene products, tuberin and hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb
AR Tee et al.
CURRENT BIOLOGY (2003)
Developmental stages of cortical Lewy bodies and their relation to axonal transport blockage in brains of patients with dementia with Lewy bodies
O Katsuse et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2003)
Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate
N Mizushima et al.
JOURNAL OF CELL SCIENCE (2003)
Paraquat and iron exposure as possible synergistic environmental risk factors in Parkinson's disease
JK Andersen
NEUROTOXICITY RESEARCH (2003)
Pathogenesis of Parkinson's disease:: Dopamine, vesicles and α-synuclein
J Lotharius et al.
NATURE REVIEWS NEUROSCIENCE (2002)
Lysosomal malfunction accompanies alpha-synuclein aggregation in a progressive mouse model of Parkinson's disease
GE Meredith et al.
BRAIN RESEARCH (2002)
Effect of mutant α-synuclein on dopamine homeostasis in a new human mesencephalic cell line
J Lotharius et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Proteasome inhibition causes nigral degeneration with inclusion bodies in rats
KS McNaught et al.
NEUROREPORT (2002)
Medicine - The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
J Hardy et al.
SCIENCE (2002)
A role for α-synuclein in the regulation of dopamine biosynthesis
RG Perez et al.
JOURNAL OF NEUROSCIENCE (2002)
Huntingtin aggregate-associated axonal degeneration is an early pathological event in Huntington's disease mice
H Li et al.
JOURNAL OF NEUROSCIENCE (2001)
Caspase 3-cleaved N-terminal fragments of wild-type and mutant huntingtin are present in normal and Huntington's disease brains, associate with membranes, and undergo calpain-dependent proteolysis
YJ Kim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Polyglutamine aggregation behavior in vitro supports a recruitment mechanism of cytotoxicity
S Chen et al.
JOURNAL OF MOLECULAR BIOLOGY (2001)
Impairment of the ubiquitin-proteasome system by protein aggregation
NF Bence et al.
SCIENCE (2001)
Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network
A Kihara et al.
EMBO REPORTS (2001)
Aggresomes, inclusion bodies and protein aggregation
RR Kopito
TRENDS IN CELL BIOLOGY (2000)
Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice
I Dragatsis et al.
NATURE GENETICS (2000)
Maturation and endosomal targeting of β-site amyloid precursor protein-cleaving enzyme -: The Alzheimer's disease β-secretase
JT Huse et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Sequestration of iron by Lewy bodies in Parkinson's disease
RJ Castellani et al.
ACTA NEUROPATHOLOGICA (2000)
High-level neuronal expression of Aβ1-42 in wild-type human amyloid protein precursor transgenic mice:: Synaptotoxicity without plaque formation
L Mucke et al.
JOURNAL OF NEUROSCIENCE (2000)
Correlation between elevated levels of amyloid β-peptide in the brain and cognitive decline
J Näslund et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2000)
α-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the Parkinsonian toxin MPTP
M Vila et al.
JOURNAL OF NEUROCHEMISTRY (2000)
MPTP induces alpha-synuclein aggregation in the substantia nigra of baboons
NW Kowall et al.
NEUROREPORT (2000)