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Stimuli-responsive electrospun nanofibers for drug delivery, cancer therapy, wound dressing, and tissue engineering

期刊

JOURNAL OF NANOBIOTECHNOLOGY
卷 21, 期 1, 页码 -

出版社

BMC
DOI: 10.1186/s12951-023-01987-z

关键词

Stimuli-responsive; Nanofibers; Electrospinning; Drug delivery; Biomedicine

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Stimuli-responsive nanofibers prepared by electrospinning are ideal materials due to their large surface area and quick response to external stimuli. As intelligent drug delivery platforms, these nanofibers can efficiently load drugs and release them on-demand under specific conditions such as light, temperature, magnetic field, ultrasound, pH or ROS, showing great potential in various biomedical applications. Therefore, this paper reviews the recent trends of stimuli-responsive electrospun nanofibers as intelligent drug delivery platforms in the field of biomedicine.
The stimuli-responsive nanofibers prepared by electrospinning have become an ideal stimuli-responsive material due to their large specific surface area and porosity, which can respond extremely quickly to external environmental incitement. As an intelligent drug delivery platform, stimuli-responsive nanofibers can efficiently load drugs and then be stimulated by specific conditions (light, temperature, magnetic field, ultrasound, pH or ROS, etc.) to achieve slow, on-demand or targeted release, showing great potential in areas such as drug delivery, tumor therapy, wound dressing, and tissue engineering. Therefore, this paper reviews the recent trends of stimuli-responsive electrospun nanofibers as intelligent drug delivery platforms in the field of biomedicine.

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