4.8 Article

Multiphoton luminescent graphene quantum dots for in vivo tracking of human adipose-derived stem cells

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NANOSCALE
卷 8, 期 16, 页码 8512-8519

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c6nr02143c

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资金

  1. Korea Health Technology R&D Project - Ministry of Health and Welfare, Republic of Korea [HI13C1479, HI14C1588]
  2. Nano-Material Technology Development Program through the National Research Foundation of Korea (NRF) - Ministry of Science, ICT and Future Planning (MSIP) [2012M3A7B4049807]
  3. Center for Advanced Soft-Electronics - MSIP as Global Frontier [CASE-2013M3A6A5073173]

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The applicability of graphene quantum dots (GQDs) for the in vitro and in vivo live imaging and tracking of different types of human stem cells is investigated. GQDs synthesized by the modified graphite intercalated compound method show efficient cellular uptake with improved biocompatibility and highly sensitive optical properties, indicating their feasibility as a bio-imaging probe for stem cell therapy.

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