期刊
NANOSCALE
卷 8, 期 6, 页码 3841-3847出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5nr06368j
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资金
- National Science Foundation of China [21473029, 91227124, 51522302]
- NASF Foundation of China [U1530260]
- National Science Foundation of Jiangsu [BK20140028]
- Science and Technology Development Program of Suzhou [ZXG2012021]
- Research Fund for the Doctoral Program of Higher Education of China [20120092130006]
- Program for New Century Excellent Talents in University
Diagnosing hematological disorders based on the separation and detection of cells in the patient's blood is a significant challenge. We have developed a novel barcode particle-based suspension array that can simultaneously capture and detect multiple types of blood cells. The barcode particles are polyacrylamide (PAAm) hydrogel inverse opal microcarriers with characteristic reflection peak codes that remain stable during cell capture on their surfaces. The hydrophilic PAAm hydrogel scaffolds of the barcode particles can entrap various plasma proteins to capture different cells in the blood, with little damage to captured cells.
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