4.6 Article

Genomic epidemiology and characterization of Staphylococcus aureus isolates from raw milk in Jiangsu, China: emerging broader host tropism strain clones ST59 and ST398

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Infectious Diseases

Multiple antibiotic resistance index (MARI) of human-isolated Salmonella species: a practical bacterial antibiotic surveillance tool

Pei Yee Woh et al.

Summary: This study aimed to determine the multiple antibiotic resistance index (MARI) of Salmonella isolated from children hospitalized for gastroenteritis in Hong Kong. The results showed that Salmonella had the highest resistance to ampicillin, ciprofloxacin, and tetracycline, while MDR strains had high resistance towards ampicillin, tetracycline, cotrimoxazole, chloramphenicol, and ciprofloxacin. MARI revealed that 80.2% of Salmonella, including all MDR strains, had indexes greater than 0.2.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2023)

Article Infectious Diseases

Genomic analyses of Staphylococcus aureus isolated from yaks in Ganzi Tibetan Autonomous Prefecture, China

Geng Zou et al.

Summary: This study investigated the transmission and origination of MRSA in yak herds with limited antimicrobial use. MRSA isolates from the yaks were found to belong to the lineage that might originate from the prevalent community-acquired MRSA ST59 in China, highlighting the role of animals in the expansion of MRSA.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2022)

Article Chemistry, Multidisciplinary

A Survey of Chinese Pig Farms and Human Healthcare Isolates Reveals Separate Human and Animal Methicillin-Resistant Staphylococcus aureus Populations

Geng Zou et al.

Summary: The study investigated the contribution of MRSA from Chinese pig farms to human infection. It found high levels of MRSA in Chinese pig farms, but no evidence of transmission to the human population. MRSA isolates from hospitals in China appear to be part of a widely distributed lineage.

ADVANCED SCIENCE (2022)

Article Microbiology

Genomic Basis of Occurrence of Cryptic Resistance among Oxacillin- and Cefoxitin-Susceptible mecA-Positive Staphylococcus aureus

Bingshao Liang et al.

Summary: The oxacillin- and cefoxitin-susceptible mecA-positive Staphylococcus aureus is a novel type of stealth MRSA that is difficult to detect using conventional methods. Whole-genome sequencing of these strains revealed mutations in the mecA gene that resulted in premature stop codon formation and a base substitution in the second promoter region. These mutations make MRSA strains difficult to detect, emphasizing the importance of combining phenotype tests with mecA or penicillin-binding protein 2a detection for MRSA identification.

MICROBIOLOGY SPECTRUM (2022)

Article Multidisciplinary Sciences

Multiclonal human origin and global expansion of an endemic bacterial pathogen of livestock

Gonzalo Yebra et al.

Summary: This study traces the evolutionary history of bovine Staphylococcus aureus and identifies seven major endemic clones causing bovine mastitis globally. The clones originated from four independent host-jump events from humans up to 2,500 years ago. The expansion of these clones coincided with the commercialization and industrialization of dairy farming. Differences in host transmission events between humans and cows were also discovered, highlighting high-risk clones that pose threats to veterinary and human health.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2022)

Article Microbiology

Staphylococcus aureus from Subclinical Cases of Mastitis in Dairy Cattle in Poland, What Are They Hiding? Antibiotic Resistance and Virulence Profile

Edyta Kaczorek-Lukowska et al.

Summary: Bovine mastitis is a common disease worldwide, and this study analyzed Staphylococcus aureus strains obtained from dairy cattle in Poland with subclinical mastitis. The study found a high prevalence of antibiotic resistance and virulence genes among the analyzed strains, as well as the dominance of biofilm over antibiotic resistance.

PATHOGENS (2022)

Article Microbiology

Prevalence of Livestock-Associated MRSA ST398 in a Swine Slaughterhouse in Guangzhou, China

Xiaoshen Li et al.

Summary: Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) is a zoonotic microorganism that poses a significant public health concern. This study investigated the transmission and occurrence of MRSA in a slaughterhouse environment and examined its antimicrobial resistance and genetic characterization. The findings suggest that MRSA is more prevalent in swine samples compared to other sources, and there is potential transmission between swine, humans, and the environment. The MRSA isolates also exhibited multidrug resistance phenotypes.

FRONTIERS IN MICROBIOLOGY (2022)

Article Microbiology

Detection of Antibiotic Resistance, Virulence Gene, and Drug Resistance Gene of Staphylococcus aureus Isolates from Bovine Mastitis

Zhe Zhang et al.

Summary: This study aimed to detect antibiotic resistance, drug resistance gene, and virulence gene of Staphylococcus aureus strains. The results showed that the strains exhibited resistance to certain antibiotics but were sensitive to nitrofurantoin and sulfamethoxazole/trimethoprim. The study provided important information for mastitis control.

MICROBIOLOGY SPECTRUM (2022)

Article Food Science & Technology

New clues about the global MRSA ST398: Emergence of MRSA ST398 from pigs in Qinghai, China

Mingquan Cui et al.

Summary: This study investigated the phenotypic and genomic characteristics of pig-associated ST398 strains in China and found that ST398 was a frequent source of MRSA and MSSA infections in Qinghai province. The study also discovered the close evolutionary relationships between livestock-associated MRSA ST398 in China and MRSA ST398 in Europe and Australia.

INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY (2022)

Article Microbiology

Characterization of Staphylococcus aureus Isolates from Bovine Mastitis and Bulk Tank Milk: First Isolation of Methicillin-Susceptible Staphylococcus aureus in Japan

Ryota Miyazawa et al.

Summary: Staphylococcus aureus is a major pathogen in humans and livestock, causing serious issues such as bovine mastitis. This study monitored cases of intramammary infection caused by S. aureus in the Miyagi Prefecture, Japan, and analyzed the strains obtained from dairy farms. The study found recurrent cases of infection and identified a Methicillin-Sensitive SA (MSSA) ST398 strain isolated from mastitis-containing cows, which is the first confirmed case in Japan. The results highlight the importance of nationwide surveillance to manage the distribution of ST398 strains in dairy farms for human and animal health.

MICROORGANISMS (2022)

Article Food Science & Technology

Effect of biofilm on the survival of Staphylococcus aureus isolated from raw milk in high temperature and drying environment

Jiawei Shen et al.

Summary: Staphylococcus aureus, a significant pathogen affecting food safety, may exhibit stress tolerance and long-term survival in dairy products. This study examined S. aureus isolates from raw milk, demonstrating high biofilm formation capability and enhanced survival rates under high temperature and dry conditions. The findings contribute to understanding the mechanisms of stress resistance of S. aureus in dairy products and aid in preventing contamination.

FOOD RESEARCH INTERNATIONAL (2021)

Article Microbiology

Genomic Distinctions of LA-MRSA ST398 on Dairy Farms From Different German Federal States With a Low Risk of Severe Human Infections

Tobias Lienen et al.

Summary: MRSA strains were found on German dairy farms, potentially causing difficult-to-treat bovine mastitis and raising the risk of transmission to humans. The isolates varied across different regions, with low risk of severe infections in humans despite widespread transmission among cattle.

FRONTIERS IN MICROBIOLOGY (2021)

Review Cell Biology

Intracellular Staphylococcus aureus and host cell death pathways

Ye Mon Soe et al.

Summary: Staphylococcus aureus is a major opportunistic human pathogen with virulence factors causing devastating infections. It adopts an intracellular lifestyle to evade host immunity and antibacterial actions, but is exposed to challenges and clearance mechanisms orchestrated by host programmed cell death pathways.

CELLULAR MICROBIOLOGY (2021)

Article Virology

Examination of Staphylococcus aureus Prophages Circulating in Egypt

Adriana Ene et al.

Summary: Staphylococcus aureus infections are on the rise in Egypt, with a majority of strains containing intact prophages encoding virulence factors. Horizontal exchange of integrases among prophages may contribute to the spread of antibiotic resistance among these strains.

VIRUSES-BASEL (2021)

Article Food Science & Technology

Staphylococcus aureus Isolated from Ruminants with Mastitis in Northern Greece Dairy Herds: Genetic Relatedness and Phenotypic and Genotypic Characterization

Charalampos Kotzamanidis et al.

Summary: This study investigated the genetic diversity and relatedness of Staphylococcus aureus strains from clinical and subclinical mastitis cases in different ruminants using molecular typing techniques. The findings revealed varying degrees of genetic relatedness, SE gene profiles, and antimicrobial resistance levels among the isolates.

TOXINS (2021)

Article Microbiology

Prevalence and Genetic Characteristics of Staphylococcus aureus CC398 Isolates From Invasive Infections in Spanish Hospitals, Focusing on the Livestock-Independent CC398-MSSA Clade

Olouwafemi Mistourath Mama et al.

Summary: The study identified differences in genetic and epidemiological characteristics between CC398-MRSA and CC398-MSSA infections in invasive human infections in Spanish hospitals. While CC398-MSSA is emerging in invasive infections, CC398-MRSA is predominantly associated with livestock and shows distinct genetic markers.

FRONTIERS IN MICROBIOLOGY (2021)

Article Microbiology

Staphylococcus aureus ST59: Concurrent but Separate Evolution of North American and East Asian Lineages

Jo-Ann McClure et al.

Summary: Detailed genetic analysis was conducted on the Staphylococcus aureus (SA) sequence type ST59, revealing the concurrent but separate evolution of North American and East Asian lineages, with extensive diversification observed in the East Asian lineage and the presence of mobile element structure (MES) as a major difference between the two continental lineages.

FRONTIERS IN MICROBIOLOGY (2021)

Article Genetics & Heredity

Drivers of methicillin-resistant Staphylococcus aureus (MRSA) lineage replacement in China

Hongbin Chen et al.

Summary: The study reveals that in China, the community-associated MRSA strain ST59 is gradually replacing the healthcare-associated strain ST239, mainly due to its higher virulence potential rather than antibiotic resistance or biofilm production. The chemotaxis inhibitory protein (chp) carried by ST59 may be a significant factor contributing to its increased virulence.

GENOME MEDICINE (2021)

Article Infectious Diseases

Characterisation of Staphylococcus aureus isolates from bovine mastitis in Ningxia, Western China

Cheng Chen et al.

Summary: This study found severe antibiotic resistance and complex molecular characteristics of Staphylococcus aureus from bovine mastitis cases in Ningxia, China. Various pathogenic factors and molecular features were identified, highlighting the need for further research on the infection and transmission of S. aureus.

JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE (2021)

Article Microbiology

Phylogenetic Tracking of LA-MRSA ST398 Intra-Farm Transmission among Animals, Humans and the Environment on German Dairy Farms

Tobias Lienen et al.

Summary: The study found that livestock-associated MRSA ST398 isolates may spread between animals, humans, and the environment on dairy farms, posing a potential risk. Hygiene practices during milking time, biosecurity measures, and pre-treatment of milk before feeding it to calves can help reduce the risk of MRSA transmission.

MICROORGANISMS (2021)

Article Immunology

Comparative analysis of genomic characteristics, fitness and virulence of MRSA ST398 and ST9 isolated from China and Germany

Xing Ji et al.

Summary: Research has shown that MRSA ST9 strains isolated from pigs in China and Germany have evolved independently, while MRSA ST398 strains in these two countries have close evolutionary relationships. Factors contributing to the success of dominant clones like ST9 in China and ST398 in Germany include resistance to common antimicrobial agents, enhanced biofilm formation ability, and resistance to desiccation. Additionally, the presence of the vwb (nu Sa alpha) gene on the genome island may partly explain their colonization fitness in pigs.

EMERGING MICROBES & INFECTIONS (2021)

Article Immunology

Reductive evolution of virulence repertoire to drive the divergence between community- and hospital-associated methicillin-resistant Staphylococcus aureus of the ST1 lineage

Marina Farrel Cortes et al.

Summary: The ST1-SCCmecIV MRSA strains in hospitals in Brazil exhibit differences in genomic and phylogenetic characteristics compared to community-acquired strains in North America. These Brazilian strains may have originated from different MSSA strains independently acquiring the SCCmecIV cassette. The Brazilian MRSA strains have adapted to the hospital environment by reducing virulence and gaining survival abilities, possibly to balance the biological cost of retaining multiple antibiotic resistance genes.

VIRULENCE (2021)

Article Infectious Diseases

Identification of a mecA/mecC-positive MRSA ST1-t127 isolate from a racehorse in Japan

Tsuyoshi Sekizuka et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2020)

Review Biochemistry & Molecular Biology

The Evolutionary Genomics of Host Specificity in Staphylococcus aureus

Marta Matuszewska et al.

TRENDS IN MICROBIOLOGY (2020)

Article Infectious Diseases

Emergence of livestock-associated MRSA ST398 from bulk tank milk, China

Mingquan Cui et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2020)

Article Biochemistry & Molecular Biology

Prophage Hunter: an integrative hunting tool for active prophages

Wenchen Song et al.

NUCLEIC ACIDS RESEARCH (2019)

Article Infectious Diseases

Biofilm formation by Staphylococcus aureus clinical isolates correlates with the infection type

Jakub M. Kwiecinski et al.

INFECTIOUS DISEASES (2019)

Editorial Material Infectious Diseases

Bacteremia caused by a mecA-positive oxacillin-susceptible Staphylococcus aureus strain with inducible resistance

Ling Yuan Kong et al.

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE (2015)

Article Food Science & Technology

Genetic diversity and virulence potential of Staphylococcus aureus isolates from raw and processed food commodities in Shanghai

Minghui Song et al.

INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY (2015)

Article Microbiology

Prevalence of the immune evasion gene cluster in Staphylococcus aureus CC398

Christiane Cuny et al.

VETERINARY MICROBIOLOGY (2015)

Article Infectious Diseases

Phages of Staphylococcus aureus and their impact on host evolution

Guoqing Xia et al.

INFECTION GENETICS AND EVOLUTION (2014)

Article Genetics & Heredity

SRST2: Rapid genomic surveillance for public health and hospital microbiology labs

Michael Inouye et al.

GENOME MEDICINE (2014)

Review Immunology

Staphylococcus aureus biofilms: recent developments in biofilm dispersal

Jessica L. Lister et al.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2014)

Article Food Science & Technology

Isolation of Methicillin-Resistant Staphylococcus aureus (MRSA) from Retail Meats in Hong Kong

Maureen V. Boost et al.

FOODBORNE PATHOGENS AND DISEASE (2013)

Article Agriculture, Dairy & Animal Science

Genetic characterization of antimicrobial resistance in coagulase-negative staphylococci from bovine mastitis milk

Yvonne Frey et al.

JOURNAL OF DAIRY SCIENCE (2013)

Review Microbiology

Staphylococcus aureus and its food poisoning toxins: characterization and outbreak investigation

Jacques-Antoine Hennekinne et al.

FEMS MICROBIOLOGY REVIEWS (2012)

Article Biochemical Research Methods

Easyfig: a genome comparison visualizer

Mitchell J. Sullivan et al.

BIOINFORMATICS (2011)