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WILEY INTERDISCIPLINARY REVIEWS-RNA (2022)
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NATURE (2022)
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NATURE (2022)
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ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis
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Decoupling expression and editing preferences of ADAR1 p150 and p110 isoforms
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IMMUNITY (2021)
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IMMUNITY (2021)
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IMMUNITY (2021)
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IMMUNITY (2021)
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CELL REPORTS (2021)
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SAUDI JOURNAL OF BIOLOGICAL SCIENCES (2021)
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CANCER RESEARCH COMMUNICATIONS (2021)
Evaluating the therapeutic potential of ADAR1 inhibition for triple-negative breast cancer
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ONCOGENE (2021)
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GENOME BIOLOGY AND EVOLUTION (2021)
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HUMAN MUTATION (2020)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
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JOURNAL OF VIROLOGY (2020)
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
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NATURE (2020)
Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency
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NATURE (2020)
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SEMINARS IN IMMUNOLOGY (2020)
The p150 Isoform of ADAR1 Blocks Sustained RLR signaling and Apoptosis during Influenza Virus Infection
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PLOS PATHOGENS (2020)
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NUCLEIC ACIDS RESEARCH (2020)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
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MOLECULAR CELL (2019)
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CELL REPORTS (2019)
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Antonio Gregorio Dias Junior et al.
TRENDS IN MICROBIOLOGY (2019)
RNA regulation of the antiviral protein 2′-5′-oligoadenylate synthetase
Samantha L. Schwartz et al.
WILEY INTERDISCIPLINARY REVIEWS-RNA (2019)
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Theodoulakis Christofi et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2019)
Double-stranded RNA deaminase ADAR1 promotes the Zika virus replication by inhibiting the activation of protein kinase PKR
Shili Zhou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade
Jeffrey J. Ishizuka et al.
NATURE (2019)
Tumor-derived IFN triggers chronic pathway agonism and sensitivity to ADAR loss
Huayang Liu et al.
NATURE MEDICINE (2019)
Inosine induces context-dependent recoding and translational stalling
Konstantin Licht et al.
NUCLEIC ACIDS RESEARCH (2019)
Sensitive ADAR editing reporter in cancer cells enables high-throughput screening of small molecule libraries
Kajsa Fritzell et al.
NUCLEIC ACIDS RESEARCH (2019)
Therapeutic Targeting of RIG-I and MDA5 Might Not Lead to the Same Rome
Dacquin M. Kasumba et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2019)
The Editor's I on Disease Development
Mamta Jain et al.
TRENDS IN GENETICS (2019)
ADAR1 function affects HPV replication and is associated to recurrent human papillomavirus-induced dysplasia in HIV coinfected individuals
Maria Pujantell et al.
SCIENTIFIC REPORTS (2019)
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
Hachung Chung et al.
CELL (2018)
Breaching Self-Tolerance to Alu Duplex RNA Underlies MDA5-Mediated Inflammation
Sadeem Ahmad et al.
CELL (2018)
A-to-I RNA editing - immune protector and transcriptome diversifier
Eli Eisenberg et al.
NATURE REVIEWS GENETICS (2018)
Global Transcriptome Analysis of RNA Abundance Regulation by ADAR in Lung Adenocarcinoma
Michael F. Sharpnack et al.
EBIOMEDICINE (2018)
A human cellular noncoding RNA activates the antiviral protein 2′-5′-oligoadenylate synthetase 1
Brenda M. Calderon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells
Hugh S. Gannon et al.
NATURE COMMUNICATIONS (2018)
Extensive editing of cellular and viral double-stranded RNA structures accounts for innate immunity suppression and the proviral activity of ADAR1(p150)
Christian K. Pfaller et al.
PLOS BIOLOGY (2018)
The Role of RNA Editing in Cancer Development and Metabolic Disorders
Che-Pei Kung et al.
FRONTIERS IN ENDOCRINOLOGY (2018)
Dynamic landscape and regulation of RNA editing in mammals
Meng How Tan et al.
NATURE (2017)
In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target
Robert T. Manguso et al.
NATURE (2017)
Genetic, Phenotypic, and Interferon Biomarker Status in ADAR1-Related Neurological Disease
Gillian I. Rice et al.
NEUROPEDIATRICS (2017)
The RNA-editing enzyme ADAR promotes lung adenocarcinoma migration and invasion by stabilizing FAK
Elianna M. Amin et al.
SCIENCE SIGNALING (2017)
Alu-dependent RNA editing of GLI1 promotes malignant regeneration in multiple myeloma
Elisa Lazzari et al.
NATURE COMMUNICATIONS (2017)
RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structure
Oz Solomon et al.
NATURE COMMUNICATIONS (2017)
The RNA-editing enzyme ADAR promotes lung adenocarcinoma migration and invasion by stabilizing FAK
Elianna M. Amin et al.
SCIENCE SIGNALING (2017)
Rewriting the transcriptome: adenosine-to-inosine RNA editing by ADARs
Carl R. Walkley et al.
GENOME BIOLOGY (2017)
Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis
Jacki E. Heraud-Farlow et al.
GENOME BIOLOGY (2017)
RNA editing-dependent epitranscriptome diversity in cancer stem cells
Qingfei Jiang et al.
NATURE REVIEWS CANCER (2017)
How do ADARs bind RNA? New protein-RNA structures illuminate substrate recognition by the RNA editing ADARs
Justin M. Thomas et al.
BIOESSAYS (2017)
A-to-I editing of coding and non-coding RNAs by ADARs
Kazuko Nishikura
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2016)
Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis
C. Anadon et al.
ONCOGENE (2016)
ADAR1, inosine and the immune sensing system: distinguishing self from non-self
Brian J. Liddicoat et al.
WILEY INTERDISCIPLINARY REVIEWS-RNA (2016)
Hyperediting by ADAR1 of a new herpesvirus lncRNA during the lytic phase of the oncogenic Marek's disease virus
Thomas Figueroa et al.
JOURNAL OF GENERAL VIROLOGY (2016)
Neurologic Phenotypes Associated with Mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR1, and IFIH1: Aicardi-Goutieres Syndrome and Beyond
John H. Livingston et al.
NEUROPEDIATRICS (2016)
Activation of RNase L is dependent on OAS3 expression during infection with diverse human viruses
Yize Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Discriminating self from non-self in nucleic acid sensing
Martin Schlee et al.
NATURE REVIEWS IMMUNOLOGY (2016)
A Specific IFIH1 Gain-of-Function Mutation Causes Singleton-Merten Syndrome
Frank Rutsch et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2015)
The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers
Leng Han et al.
CANCER CELL (2015)
DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts
David Roulois et al.
CELL (2015)
Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses
Katherine B. Chiappinelli et al.
CELL (2015)
Isoforms of RNA-Editing Enzyme ADAR1 Independently Control Nucleic Acid Sensor MDA5-Driven Autoimmunity and Multi-organ Development
Kathleen Pestal et al.
IMMUNITY (2015)
Recognition of duplex RNA by the deaminase domain of the RNA editing enzyme ADAR2
Kelly J. Phelps et al.
NUCLEIC ACIDS RESEARCH (2015)
RNA EDITING RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself
Brian J. Liddicoat et al.
SCIENCE (2015)
The ADAR1 editing enzyme is encapsidated into HIV-1 virions
Elisa Orecchini et al.
VIROLOGY (2015)
Elevated RNA Editing Activity Is a Major Contributor to Transcriptomic Diversity in Tumors
Nurit Paz-Yaacov et al.
CELL REPORTS (2015)
Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome
Debora Fumagalli et al.
CELL REPORTS (2015)
MDA5-filament, dynamics and disease
Yoandris del Toro Duany et al.
CURRENT OPINION IN VIROLOGY (2015)
IFIH1 Mutation Causes Systemic Lupus Erythematosus With Selective IgA Deficiency
Lien Van Eyck et al.
ARTHRITIS & RHEUMATOLOGY (2015)
A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma
Tim Hon Man Chan et al.
GUT (2014)
Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling
Gillian I. Rice et al.
NATURE GENETICS (2014)
RADAR: a rigorously annotated database of A-to-I RNA editing
Gokul Ramaswami et al.
NUCLEIC ACIDS RESEARCH (2014)
Genome-wide analysis of Alu editability
Lily Bazak et al.
NUCLEIC ACIDS RESEARCH (2014)
The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA
Niamh M. Mannion et al.
CELL REPORTS (2014)
Stress Granule Formation Induced by Measles Virus Is Protein Kinase PKR Dependent and Impaired by RNA Adenosine Deaminase ADAR1
Kristina M. Okonski et al.
JOURNAL OF VIROLOGY (2013)
Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma
Lei Lei Chen et al.
NATURE MEDICINE (2013)
Proteins that contain a functional Z-DNA-binding domain localize to cytoplasmic stress granules
Siew Kit Ng et al.
NUCLEIC ACIDS RESEARCH (2013)
Adenosine Deaminase Acting on RNA 1 (ADAR1) Suppresses the Induction of Interferon by Measles Virus
Zhiqun Li et al.
JOURNAL OF VIROLOGY (2012)
Mutations in ADAR1 cause Aicardi-Goutieres syndrome associated with a type I interferon signature
Gillian I. Rice et al.
NATURE GENETICS (2012)
Accurate identification of human Alu and non-Alu RNA editing sites
Gokul Ramaswami et al.
NATURE METHODS (2012)
The ADAR protein family
Yiannis A. Savva et al.
GENOME BIOLOGY (2012)
Adenosine Deaminases Acting on RNA, RNA Editing, and Interferon Action
Cyril X. George et al.
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2011)
RNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesis
Simone V. Ward et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Adenosine deaminases acting on RNA (ADARs) are both antiviral and proviral
Charles E. Samuel
VIROLOGY (2011)
Functions and Regulation of RNA Editing by ADAR Deaminases
Kazuko Nishikura
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 79 (2010)
Extracellular 2′-5′ Oligoadenylate Synthetase Stimulates RNase L-Independent Antiviral Activity: a Novel Mechanism of Virus-Induced Innate Immunity
Helle Kristiansen et al.
JOURNAL OF VIROLOGY (2010)
Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses
Trine H. Mogensen
CLINICAL MICROBIOLOGY REVIEWS (2009)
RNA-specific Adenosine Deaminase ADAR1 Suppresses Measles Virus-induced Apoptosis and Activation of Protein Kinase PKR
Ann M. Toth et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
ADAR1 Interacts with PKR during Human Immunodeficiency Virus Infection of Lymphocytes and Contributes to Viral Replication
Guerline Clerzius et al.
JOURNAL OF VIROLOGY (2009)
ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling
Jochen C. Hartner et al.
NATURE IMMUNOLOGY (2009)
Adenosine-to-inosine RNA editing
Boris Zinshteyn et al.
WILEY INTERDISCIPLINARY REVIEWS-SYSTEMS BIOLOGY AND MEDICINE (2009)
Alu element-mediated gene silencing
Ling-Ling Chen et al.
EMBO JOURNAL (2008)
Rates of evolutionary change in viruses: patterns and determinants
Siobain Duffy et al.
NATURE REVIEWS GENETICS (2008)
Interferon-inducible antiviral effectors
Anthony J. Sadler et al.
NATURE REVIEWS IMMUNOLOGY (2008)
A left-handed RNA double helix bound by the Zα domain of the RNA-editing enzyme ADAR1
Diana Placido et al.
STRUCTURE (2007)
Double-stranded RNA deaminase ADAR1 increases host susceptibility to virus infection
Yongzhan Nie et al.
JOURNAL OF VIROLOGY (2007)
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′-phosphates
Andreas Pichlmair et al.
SCIENCE (2006)
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
H Kato et al.
NATURE (2006)
New antiviral pathway that mediates hepatitis C virus replicon interferon sensitivity through ADAR1
DR Taylor et al.
JOURNAL OF VIROLOGY (2005)
Expression of interferon-inducible RNA adenosine deaminase ADAR1 during pathogen infection and mouse embryo development involves tissue-selective promoter utilization and alternative splicing
CX George et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Modulation of ADAR1 editing activity by Z-RNA in vitro
M Koeris et al.
NUCLEIC ACIDS RESEARCH (2005)
Stress-induced apoptosis associated with null mutation of ADAR1 RNA editing deaminase gene
QD Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Systematic identification of abundant A-to-I editing sites in the human transcriptome
EY Levanon et al.
NATURE BIOTECHNOLOGY (2004)
A survey of RNA editing in human brain
M Blow et al.
GENOME RESEARCH (2004)
Resistance to vesicular stomatitis virus infection requires a functional cross talk between the eukarvotic translation initiation factor 2α kinases PERK and PKR
D Baltzis et al.
JOURNAL OF VIROLOGY (2004)
Widespread A-to-I RNA editing of alu-containing mRNAs in the human transcriptome
A Athanasiadis et al.
PLOS BIOLOGY (2004)
Replicating hepatitis delta virus RNA is edited in the nucleus by the small form of ADAR1
SK Wong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Nucleocytoplasmic distribution of human RNA-editing enzyme ADAR1 is modulated by double-stranded RNA-binding domains, a leucine-rich export signal, and a putative dimerization domain
A Strehblow et al.
MOLECULAR BIOLOGY OF THE CELL (2002)
Increased RNA editing and inhibition of hepatitis delta virus replication by high-level expression of ADAR1 and ADAR2
GC Jayan et al.
JOURNAL OF VIROLOGY (2002)
The role of binding domains for dsRNA and Z-DNA in the in vivo editing of minimal substrates by ADAR1
A Herbert et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Requirement of the RNA editing deaminase ADAR1 gene for embryonic erythropoiesis
Q Wang et al.
SCIENCE (2000)
A third member of the RNA-specific adenosine deaminase gene family, ADAR3, contains both single- and double-stranded RNA binding domains
CX Chen et al.
RNA (2000)
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