期刊
TOXINS
卷 15, 期 9, 页码 -出版社
MDPI
DOI: 10.3390/toxins15090545
关键词
botulinum neurotoxins; Clostridium; nomenclature; taxonomy
Botulinum neurotoxins are a group of protein toxins with similar structures and activities, produced by different bacteria. The nomenclature of these toxins and bacteria has been evolving, which is crucial for accurate reporting of information.
Botulinum neurotoxins are a varied group of protein toxins that share similar structures and modes of activity. They include at least seven serotypes and over forty subtypes that are produced by seven different clostridial species. These bacterial species are not limited strictly to BoNT-producers as neuro-toxigenic and non-neuro-toxigenic members have been identified within each species. The nomenclature surrounding these toxins and associated bacteria has been evolving as new isolations and discoveries have arisen, resulting in challenges in diagnostic reporting, epidemiology and food safety studies, and in the application of therapeutic products. An understanding of the intricacies regarding the nomenclature of BoNTs and BoNT-producing clostridia is crucial for communication that allows for accurate reporting of information that is pertinent to each situation.
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