期刊
POLYMERS
卷 15, 期 17, 页码 -出版社
MDPI
DOI: 10.3390/polym15173497
关键词
bioceramics; modified cellulose nanofibers; bioactive glass; biomineralization activity
Developing bioactive implants with strong mechanical properties and biomineralization activity is crucial for bone repair. In this study, modified cellulose nanofiber (mCNF)-reinforced bioactive glass (BG)-polycaprolactone (PCL) hybrids (mCNF-BP) with strong biomechanics and good apatite formation ability were successfully developed. The incorporation of mCNFs significantly improved the forming duration, biomechanical performance, and in vitro apatite-formation capability of the hybrid materials.
Developing bioactive implants with strong mechanical properties and biomineralization activity is critical in bone repair. In this work, modified cellulose nanofiber (mCNF)-reinforced bioactive glass (BG)-polycaprolactone (PCL) hybrids (mCNF-BP) with strong biomechanics and good apatite formation ability were reported. Incorporating mCNFs shortens the forming duration of the hybrid films and enhances the biomechanical performance and in vitro apatite-formation capability. The optimized biomechanical performance of the optimal hybrid materials is produced at a relatively high mCNF content (1.0 wt%), including a considerably higher modulus of elasticity (948.65 & PLUSMN; 74.06 MPa). In addition, the biomineralization activity of mCNF-BP hybrids is also tailored with the increase in the mCNF contents. The mCNF-BP with 1.5 wt% and 2.0 wt% mCNFs demonstrate the best biomineralization activity after immersing in simulated body fluid for 3 days. This study suggests that mCNFs are efficient bioactive additive to reinforce BG-based hybrids' mechanical properties and biomineralization activity.
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