The presence and severity of neuropsychiatric symptoms and their association with quality of life among patients with dementia

Article Psychiatry

Distinguishing apathy and depression in dementia: A longitudinal study

Michael H. Connors et al.

Summary: The study found that apathy increases over the course of dementia and is associated with worse clinical outcomes. Distinguishing apathy and depression is important as they have different implications for prognosis and management.

AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY (2023)

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Article Geriatrics & Gerontology

Association between Clinical Frailty Scale (CFS) and clinical presentation and outcomes in older inpatients with COVID-19

Ana Marti-Pastor et al.

Summary: This study aimed to evaluate the relationship between clinical presentation, analytical and radiological parameters, and frailty in older people hospitalized with COVID-19. The study found that frail patients often presented with atypical symptoms such as less dry cough, myalgia-arthralgia, and anosmia-dysgeusia, and more confusion. Frailty was an independent predictor for death regardless of severity, and mild-moderate frailty was associated with readmission.

BMC GERIATRICS (2023)

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Article Geriatrics & Gerontology

The use of digital touch screen technology to deliver reminiscence therapy among people with dementia in Jordanian care homes: a mixed-method feasibility study

Asem Abdalrahim et al.

Summary: This study aimed to explore the feasibility and acceptability of using digital touch screen technology to deliver reminiscence therapy (RT) in Jordanian care homes. The results showed that digital RT intervention is feasible and acceptable, and it can be effective in improving the mental health and communication abilities of people with dementia.

PSYCHOGERIATRICS (2022)

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Article Geriatrics & Gerontology

Education level is associated with neuropsychiatric symptoms in patients with amnestic-mild cognitive impairment

Keisuke Inamura et al.

Summary: This study examined the differences in severity of neuropsychiatric symptom subsyndromes among patients with amnestic-mild cognitive impairment (a-MCI) according to their education level. The results showed that aggressiveness and apathy/eating problems differed according to education level in a-MCI patients. The study suggests that when determining the need for interventions for neuropsychiatric symptoms, factors other than education level should also be considered.

PSYCHOGERIATRICS (2022)

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Article Nursing

The impact of confinement on older Jordanian adults' mental distress during the COVID-19 pandemic: A web-based cross-sectional study

Andaleeb K. Abu Kamel et al.

Summary: The study found that older Jordanian adults experienced varying levels of mental distress during the COVID-19 confinement, with fear and intrusion effects being more prominent. Early assessment and intervention are recommended to mitigate the impacts of confinement.

PERSPECTIVES IN PSYCHIATRIC CARE (2022)

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Review Gerontology

Environmental and Caregivers-Related Factors Influencing the Psychosocial Well-Being of Older Adults with Dementia: A Systematic Review

Mohammad Rababa et al.

Summary: Dementia is a neurologically caused deterioration in cognitive functions that negatively affects older adults' lives. Research has shown that environmental and caregiver-related factors significantly influence the psychological and behavioral well-being of people with dementia.

AGEING INTERNATIONAL (2022)

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Article Psychiatry

A multicentric exploratory study of behavioral and psychological symptom characteristics of dementia

Shreekantiah Umesh et al.

Summary: This study examined the characteristics and inter-relationship of behavioral and psychological symptoms (BPS) in dementia patients, with a focus on symptom clusters. The findings provide valuable insights for clinicians assessing patients with dementia.

INDIAN JOURNAL OF PSYCHIATRY (2022)

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Article Clinical Neurology

Assessment of neuropsychiatric symptoms in dementia: validity and reliability of the Lebanese version of the neuropsychiatric inventory questionnaire

Yara Feghali et al.

Summary: The study aimed to examine the psychometric properties of an Arabic version of the Neuropsychiatric Inventory Questionnaire (NPI-Q) for Lebanese dementia patients, showing evidence of good reliability and validity. The Arabic version of the NPI-Q is deemed suitable for routine assessment of neuropsychiatric symptoms in clinical settings for patients with dementia in Lebanon.

APPLIED NEUROPSYCHOLOGY-ADULT (2021)

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Article Clinical Neurology

Sex differences in neuropsychiatric symptoms in Alzheimer’s disease dementia: A meta‐analysis

Willem S. Eikelboom et al.

Alzheimers & Dementia (2021)

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Article Neurosciences

The Longitudinal Assessment of Neuropsychiatric Symptoms in Mild Cognitive Impairment and Alzheimer's Disease and Their Association With White Matter Hyperintensities in the National Alzheimer's Coordinating Center's Uniform Data Set

Cassandra J. Anor et al.

Summary: The study found a significant relationship between baseline white matter hyperintensities (WMHs) and the severity of neuropsychiatric symptoms (NPSs) in Mild Cognitive Impairment due to Alzheimer's Disease (MCI-AD) and Alzheimer's Disease (AD). It suggests that WMHs can predict future NPS progression, highlighting the importance of aggressive treatment of vascular risk factors in patients with MCI-AD or AD to improve patient outcomes.

BIOLOGICAL PSYCHIATRY-COGNITIVE NEUROSCIENCE AND NEUROIMAGING (2021)

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Article Psychiatry

Relationship between the severity of agitation and quality of life in residents with dementia living in German nursing homes-a secondary data analysis

Kathrin Schmuedderich et al.

Summary: The study revealed a negative correlation between the severity of agitation and dimensions of quality of life such as social isolation, restless tense behavior, positive affect, and social relations among dementia patients in nursing homes.

BMC PSYCHIATRY (2021)

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Review Geriatrics & Gerontology

Uses of reminiscence intervention to address the behavioral and psychosocial problems associated with dementia: An integrative review

Abdallah Abu Khait et al.

Summary: This integrative review synthesized research on the health benefits of reminiscence intervention for people with dementia, identifying improvements in depressive symptoms, enhancement of cognitive functions, and fulfilling life in late adulthood. It emphasizes the need for future studies to improve methodological rigor for conclusive evidence.

GERIATRIC NURSING (2021)

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Article Geriatrics & Gerontology

Gender Differences in Neuropsychiatric Symptoms Among Community-Dwelling Mexican Americans Aged 80 and Older

Sadaf Arefi Milani et al.

Summary: The study found that among Mexican American community-dwelling individuals aged 80 and above, women were more likely to have dysphoria/depression and anxiety, while men had lower odds of agitation/aggression. Recognizing these gender differences in neuropsychiatric symptoms could help tailor appropriate screening and treatment programs.

AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS (2021)

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Article Gerontology

Collecting self-report research data with people with dementia within care home clinical trials: Benefits, challenges and best practice

Devon Perfect et al.

Summary: Researchers have explored the experiences and challenges of data collection with people with dementia in care homes, and identified methods to overcome these challenges. Benefits of data collection include improving person-centered care delivery, listening to the voice of people with dementia, and having an evidence base from multiple sources. Challenges include effective communication, fluctuating capacity, causing distress to residents, time pressures, and staff availability.

DEMENTIA-INTERNATIONAL JOURNAL OF SOCIAL RESEARCH AND PRACTICE (2021)

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Article Geriatrics & Gerontology

Natural course of neuropsychiatric symptoms in nursing home patients with mental-physical multimorbidity in the first eight months after admission

Anne van den Brink et al.

AGING & MENTAL HEALTH (2020)

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Article Geriatrics & Gerontology

Neuropsychiatric Symptoms and Risk Factors in Mild Cognitive Impairment: A Cohort Investigation of Elderly Patients

A. -N. Yang et al.

JOURNAL OF NUTRITION HEALTH & AGING (2020)

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Review Geriatrics & Gerontology

Neuropsychiatric Symptoms in Mild Cognitive Impairment: A Literature Review

Evangelia Martin et al.

DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2020)

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Article Geriatrics & Gerontology

Factors influencing the deterioration from cognitive decline of normal aging to dementia among nursing home residents

Audai A. Hayajneh et al.

BMC GERIATRICS (2020)

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Article Neuroimaging

Multivariate neuroanatomical correlates of behavioral and psychological symptoms in dementia and the moderating role of education

Seyul Kwak et al.

NEUROIMAGE-CLINICAL (2020)

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Article Geriatrics & Gerontology

Determinants of self- and carer-rated quality of life and caregiver burden in Alzheimer disease

Christin Schumann et al.

INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY (2019)

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Article Neurosciences

An Arabic Version of the Mini-Mental State Examination for the Lebanese Population: Reliability, Validity, and Normative Data

Rita El-Hayeck et al.

JOURNAL OF ALZHEIMERS DISEASE (2019)

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Article Neurosciences

Vital Exhaustion and Incidence of Dementia: Results from the Copenhagen City Heart Study

Sabrina Islamoska et al.

JOURNAL OF ALZHEIMERS DISEASE (2019)

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Article Geriatrics & Gerontology

Severity of both neuropsychiatric symptoms and dementia is associated with quality of life in nursing home residents

Hanna-Maria Roitto et al.

EUROPEAN GERIATRIC MEDICINE (2019)

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Article Clinical Neurology

Time course of neuropsychiatric symptoms and cognitive diagnosis in National Alzheimer's Coordinating Centers volunteers

Elizabeth A. Wise et al.

ALZHEIMER'S & DEMENTIA: DIAGNOSIS, ASSESSMENT & DISEASE MONITORING (2019)

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Article Geriatrics & Gerontology

Sex Differences in the Neuropsychiatric Symptoms of Patients With Alzheimer's Disease

Ye Tao et al.

AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS (2018)

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Article Geriatrics & Gerontology

Course of neuropsychiatric symptoms in dementia: 5-year longitudinal study

Audun Osland Vik-Mo et al.

INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY (2018)

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Article Public, Environmental & Occupational Health

Gender Differences in Neuropsychiatric Symptoms in Mild to Moderate Alzheimer's Disease Patients Undergoing Switch of Cholinesterase Inhibitors: A Post Hoc Analysis of the EVOLUTION Study

Delia Colombo et al.

JOURNAL OF WOMENS HEALTH (2018)

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Correction Multidisciplinary Sciences

The course of neuropsychiatric symptoms in nursing home residents from admission to 30-month follow-up (vol 13, e0206147, 2018)

Anne-Sofie Helvik et al.

PLOS ONE (2018)

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Article Clinical Neurology

Pain, Neuropsychiatric Symptoms, and Quality of Life of Nursing Home Residents With Advanced Dementia in The Netherlands A Cross-sectional Study

Janine van Kooten et al.

ALZHEIMER DISEASE & ASSOCIATED DISORDERS (2017)

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Article Clinical Neurology

Associations between Pain and Quality of Life in Severe Dementia: A Norwegian Cross-Sectional Study

Hanne Marie Rostad et al.

DEMENTIA AND GERIATRIC COGNITIVE DISORDERS EXTRA (2017)

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Article Geriatrics & Gerontology

Effects of anosognosia and neuropsychiatric symptoms on the quality of life of patients with Alzheimer's disease: a 24-month follow-up study

Josep L. Conde-Sala et al.

INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY (2016)

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Article Psychology, Clinical

EDUCATIONAL ATTAINMENT AS A PROTECTIVE FACTOR FOR PSYCHIATRIC DISORDERS: FINDINGS FROM A NATIONALLY REPRESENTATIVE LONGITUDINAL STUDY

Julie Erickson et al.

DEPRESSION AND ANXIETY (2016)

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Article Clinical Neurology

The prevalence of neuropsychiatric symptoms in Alzheimer's disease: Systematic review and meta-analysis

Qing-Fei Zhao et al.

JOURNAL OF AFFECTIVE DISORDERS (2016)

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Article Clinical Neurology

Gender Differences in Alzheimer Disease: Brain Atrophy, Histopathology Burden, and Cognition

Jessica R. Filon et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2016)

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Article Geriatrics & Gerontology

Exploring the prevalence and variance of cognitive impairment, pain, neuropsychiatric symptoms and ADL dependency among persons living in nursing homes; a cross-sectional study

Sabine Bjork et al.

BMC GERIATRICS (2016)

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Article Public, Environmental & Occupational Health

Reflections and Recommendations for Conducting In-Depth Interviews With People With Dementia

Elizabeth K. Cridland et al.

QUALITATIVE HEALTH RESEARCH (2016)

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Editorial Material Psychiatry

Neuropsychiatric Symptoms in Dementia: A Cause or Consequence?

Anton P. Porsteinsson et al.

AMERICAN JOURNAL OF PSYCHIATRY (2015)

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Article Geriatrics & Gerontology

The Course of Neuropsychiatric Symptoms in Dementia: A 3-Year Longitudinal Study

Henry Brodaty et al.

JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION (2015)

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Article Clinical Neurology

Sensitivity to change and prediction of global change for the Alzheimer's Questionnaire

Michael Malek-Ahmadi et al.

ALZHEIMERS RESEARCH & THERAPY (2015)

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Article Geriatrics & Gerontology

Management of Neuropsychiatric Symptoms of Dementia in Clinical Settings: Recommendations from a Multidisciplinary Expert Panel

Helen C. Kales et al.

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2014)

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Article Multidisciplinary Sciences

Variables Associated with Change in Quality of Life among Persons with Dementia in Nursing Homes: A 10 Months Follow-Up Study

Marit Mjorud et al.

PLOS ONE (2014)

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Article Geriatrics & Gerontology

A short measure of quality of life in older age: The performance of the brief Older People's Quality of Life questionnaire (OPQOL-brief)

Ann Bowling et al.

ARCHIVES OF GERONTOLOGY AND GERIATRICS (2013)

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Article Health Care Sciences & Services

Older People's Quality of Life (OPQOL) scores and adverse health outcomes at a one-year follow-up. A prospective cohort study on older outpatients living in the community in Italy

Claudio Bilotta et al.

HEALTH AND QUALITY OF LIFE OUTCOMES (2011)

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Article Geriatrics & Gerontology

Predictors of neuropsychiatric symptoms in nursing home patients: influence of gender and dementia severity

Sytse U. Zuidema et al.

INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY (2009)

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Review Neurosciences

A Systematic Review of Neuropsychiatric Symptoms in Mild Cognitive Impairment

Roberto Monastero et al.

JOURNAL OF ALZHEIMERS DISEASE (2009)

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Article Mathematical & Computational Biology

Purposeful selection of variables in logistic regression

Zoran Bursac et al.

SOURCE CODE FOR BIOLOGY AND MEDICINE (2008)

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Article Psychology, Mathematical

G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences

Franz Faul et al.

BEHAVIOR RESEARCH METHODS (2007)

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Article Psychology, Clinical

Psychometric properties of the folstein mini-mental state examination

M Lopez et al.

ASSESSMENT (2005)

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The presence and severity of neuropsychiatric symptoms and their association with quality of life among patients with dementia

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