4.8 Article

Low dietary fiber intake impairs small intestinal Th17 and intraepithelial T cell development over generations

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Microbiology

Human gut bacterial metabolism drives Th17 activation and colitis

Margaret Alexander et al.

Summary: The activation of Th17 cells by human gut bacteria Eggerthella lenta exacerbates inflammatory bowel disease. Variations in E. lenta strains and the Cgr2 enzyme contribute to Th17 cell activation. Blocking E. lenta-induced intestinal inflammation is crucial for preventing the development of autoimmune diseases.

CELL HOST & MICROBE (2022)

Editorial Material Microbiology

Microbial Cgr2 will let your Th17 cells ROR(γT)

Naomi Rodriguez-Marino et al.

Summary: The enzyme cardiac glycoside reductase 2 (cgr2), produced by Eggerthella lenta, metabolizes ROR gamma T inhibitors, leading to increased Th17 response and more severe inflammation in colitis models. The effect of cgr2 can be counteracted by a diet rich in arginine.

CELL HOST & MICROBE (2022)

Article Biochemistry & Molecular Biology

Microbiota imbalance induced by dietary sugar disrupts immune-mediated protection from metabolic syndrome

Yoshinaga Kawano et al.

Summary: Intestinal microbes protect against obesity and metabolic syndrome by inducing commensal-specific Th17 cells. High-fat, high-sugar diet depletes Th17-inducing microbes and promotes metabolic disease, while recovery of commensal Th17 cells restores protection. Th17 cells regulate lipid absorption across the intestinal epithelium in an IL-17-dependent manner. Dietary sugar and the presence of Faecalibaculum rodentium displace Th17-inducing microbiota and contribute to the immuno-pathogenicity of sugar.
Article Immunology

Embryonic macrophages function during early life to determine invariant natural killer T cell levels at barrier surfaces

Thomas Gensollen et al.

Summary: The study uncovers an important mechanism of immune development within the colon controlled by embryo-derived macrophages, which is associated with the decreased number of iNKT cells in infants and later susceptibility or resistance to iNKT cell-associated mucosal disorders. This mechanism is regulated by microbiota and reveals the crucial postnatal function of macrophages emerging in fetal life.

NATURE IMMUNOLOGY (2021)

Article Biochemistry & Molecular Biology

Ketogenic Diets Alter the Gut Microbiome Resulting in Decreased Intestinal Th17 Cells

Qi Yan Ang et al.

Review Immunology

Deconstructing Mechanisms of Diet-Microbiome-Immune Interactions

Margaret Alexander et al.

IMMUNITY (2020)

Letter Biotechnology & Applied Microbiology

Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2

Evan Bolyen et al.

NATURE BIOTECHNOLOGY (2019)

Article Multidisciplinary Sciences

Effects of microbiota-directed foods in gnotobiotic animals and undernourished children

Jeanette L. Gehrig et al.

SCIENCE (2019)

Article Biochemistry & Molecular Biology

Segmented Filamentous Bacteria Prevent and Cure Rotavirus Infection

Zhenda Shi et al.

Review Immunology

Diverse developmental pathways of intestinal intraepithelial lymphocytes

Benjamin D. McDonald et al.

NATURE REVIEWS IMMUNOLOGY (2018)

Article Multidisciplinary Sciences

Lactobacillus reuteri induces gut intraepithelial CD4+CD8αα+ T cells

Luisa Cervantes-Barragan et al.

SCIENCE (2017)

Review Multidisciplinary Sciences

The microbiota in adaptive immune homeostasis and disease

Kenya Honda et al.

NATURE (2016)

Review Multidisciplinary Sciences

Diet-microbiota interactions as moderators of human metabolism

Justin L. Sonnenburg et al.

NATURE (2016)

Article Multidisciplinary Sciences

Diet-induced extinctions in the gut microbiota compound over generations

Erica D. Sonnenburg et al.

NATURE (2016)

Article Biochemical Research Methods

DADA2: High-resolution sample inference from Illumina amplicon data

Benjamin J. Callahan et al.

NATURE METHODS (2016)

Article Multidisciplinary Sciences

Identifying species of symbiont bacteria from the human gut that, alone, can induce intestinal Th17 cells in mice

Tze Guan Tan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Multidisciplinary Sciences

Tissue adaptation of regulatory and intraepithelial CD4+ T cells controls gut inflammation

Tomohisa Sujino et al.

SCIENCE (2016)

Article Gastroenterology & Hepatology

Lack of soluble fiber drives diet-induced adiposity in mice

Benoit Chassaing et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2015)

Review Gastroenterology & Hepatology

Epidemiology and risk factors for IBD

Ashwin N. Ananthakrishnan

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2015)

Review Immunology

The light and dark sides of intestinal intraepithelial lymphocytes

Hilde Cheroutre et al.

NATURE REVIEWS IMMUNOLOGY (2011)

Letter Biochemical Research Methods

QIIME allows analysis of high-throughput community sequencing data

J. Gregory Caporaso et al.

NATURE METHODS (2010)

Article Multidisciplinary Sciences

FastTree 2-Approximately Maximum-Likelihood Trees for Large Alignments

Morgan N. Price et al.

PLOS ONE (2010)

Article Gastroenterology & Hepatology

Dietary glutamine and oral antibiotics each improve indexes of gut barrier function in rat short bowel syndrome

Junqiang Tian et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2009)

Article Biochemistry & Molecular Biology

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

Ivaylo I. Ivanov et al.

Review Immunology

Differentiation and function of Th17 T cells

Brigitta Stockinger et al.

CURRENT OPINION IN IMMUNOLOGY (2007)

Article Multidisciplinary Sciences

An important regulatory role for CD4+CD8αα T cells in the intestinal epithelial layer in the prevention of inflammatory bowel disease

G Das et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Nutrition & Dietetics

On defining dietary fibre

JW DeVries

PROCEEDINGS OF THE NUTRITION SOCIETY (2003)

Article Biochemistry & Molecular Biology

MAFFT: a novel method for rapid multiple sequence alignment based on fast Fourier transform

K Katoh et al.

NUCLEIC ACIDS RESEARCH (2002)