相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Beyond Good and Evil: Molecular Mechanisms of Type I and III IFN Functions
Jack W. Dowling et al.
JOURNAL OF IMMUNOLOGY (2022)
Biological functions of DEAD/DEAH-box RNA helicases in health and disease
Ourania Andrisani et al.
NATURE IMMUNOLOGY (2022)
Ddx41 inhibition of DNA damage signaling permits erythroid progenitor expansion in zebrafish
Joshua T. Weinreb et al.
HAEMATOLOGICA (2022)
Mechanisms of Antiviral Immune Evasion of SARS-CoV-2
Daniel Beyer et al.
JOURNAL OF MOLECULAR BIOLOGY (2022)
Walking a tightrope The complex balancing act of R-loops in genome stability
Joshua R. Brickner et al.
MOLECULAR CELL (2022)
Nuclear antiviral innate responses at the intersection of DNA sensing and DNA repair
Joshua L. Justice et al.
TRENDS IN MICROBIOLOGY (2022)
RNase H2, mutated in Aicardi-Goutieres syndrome, resolves co-transcriptional R-loops to prevent DNA breaks and inflammation
Agnese Cristini et al.
NATURE COMMUNICATIONS (2022)
DDX41 is required for cGAS-STING activation against DNA virus infection
Ravi Shankar Singh et al.
CELL REPORTS (2022)
DDX41 is needed for pre- and postnatal hematopoietic stem cell differentiation in mice
Jing Ma et al.
STEM CELL REPORTS (2022)
Excessive R-loops trigger an inflammatory cascade leading to increased HSPC production
Joshua T. Weinreb et al.
DEVELOPMENTAL CELL (2021)
Type I interferon response-related microglial Mef2c deregulation at the onset of Alzheimer's pathology in 5xFAD mice
Feng Xue et al.
NEUROBIOLOGY OF DISEASE (2021)
Aicardi-Goutieres syndrome-associated gene SAMHD1 preserves genome integrity by preventing R-loop formation at transcription-replication conflict regions
Kiwon Park et al.
PLOS GENETICS (2021)
CellProfiler 4: improvements in speed, utility and usability
David R. Stirling et al.
BMC BIOINFORMATICS (2021)
Germline DDX41 mutations cause ineffective hematopoiesis and myelodysplasia
Timothy M. Chlon et al.
CELL STEM CELL (2021)
ETV7 limits antiviral gene expression and control of influenza viruses
Heather M. Froggatt et al.
SCIENCE SIGNALING (2021)
Endomembrane targeting of human OAS1 p46 augments antiviral activity
Frank W. Soveg et al.
ELIFE (2021)
DEAD-Box RNA Helicases and Genome Stability
Michael Cargill et al.
GENES (2021)
Regulation of IFN-Is by MEF2D Promotes Inflammatory Homeostasis in Microglia
Fangfang Lu et al.
JOURNAL OF INFLAMMATION RESEARCH (2021)
R-loop proximity proteomics identifies a role of DDX41 in transcription-associated genomic instability
Thorsten Mosler et al.
NATURE COMMUNICATIONS (2021)
The cGAS-STING pathway as a therapeutic target in inflammatory diseases
Alexiane Decout et al.
NATURE REVIEWS IMMUNOLOGY (2021)
Treatments in Aicardi-Goutieres syndrome
Yanick J. Crow et al.
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY (2020)
ATR Protects the Genome against R Loops through a MUS81-Triggered Feedback Loop
Dominick A. Matos et al.
MOLECULAR CELL (2020)
Regulation of cGAS- and RLR-mediated immunity to nucleic acids
Andrea Ablasser et al.
NATURE IMMUNOLOGY (2020)
Human DNA-PK activates a STING-independent DNA sensing pathway
Katelyn Burleigh et al.
SCIENCE IMMUNOLOGY (2020)
Replication Stress, DNA Damage, Inflammatory Cytokines and Innate Immune Response
Sandrine Ragu et al.
GENES (2020)
The myeloid type I interferon response to myocardial infarction begins in bone marrow and is regulated by Nrf2-activated macrophages
David M. Calcagno et al.
SCIENCE IMMUNOLOGY (2020)
From APOBEC to ZAP: Diverse mechanisms used by cellular restriction factors to inhibit virus infections
Mahesh Chemudupati et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2019)
R-Loops as Cellular Regulators and Genomic Threats
Madzia P. Crossley et al.
MOLECULAR CELL (2019)
Viral Generated Inter-Organelle Contacts Redirect Lipid Flux for Genome Replication
Orly Laufman et al.
CELL (2019)
Differential Activation of the Transcription Factor IRF1 Underlies the Distinct Immune Responses Elicited by Type I and Type III Interferons
Adriana Forero et al.
IMMUNITY (2019)
RNA-binding protein isoforms ZAP-S and ZAP-L have distinct antiviral and immune resolution functions
Johannes Schwerk et al.
NATURE IMMUNOLOGY (2019)
Chromatin Environment and Cellular Context Specify Compensatory Activity of Paralogous MEF2 Transcription Factors
Shahriyar P. Majidi et al.
CELL REPORTS (2019)
A mitosis-specific and R loop-driven ATR pathway promotes faithful chromosome segregation
Lilian Kabeche et al.
SCIENCE (2018)
The Augmented R-Loop Is a Unifying Mechanism for Myelodysplastic Syndromes Induced by High-Risk Splicing Factor Mutations
Liang Chen et al.
MOLECULAR CELL (2018)
ATR-mediated proteome remodeling is a major determinant of homologous recombination capacity in cancer cells
Dongsung Kim et al.
NUCLEIC ACIDS RESEARCH (2018)
DDX41 Recognizes RNA/DNA Retroviral Reverse Transcripts and Is Critical for In Vivo Control of Murine Leukemia Virus Infection
Spyridon Stavrou et al.
MBIO (2018)
Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage
Gillian Dunphy et al.
MOLECULAR CELL (2018)
DHX9 helicase promotes R-loop formation in cells with impaired RNA splicing
Prasun Chakraborty et al.
NATURE COMMUNICATIONS (2018)
Antagonistic regulation of cell-cycle and differentiation gene programs in neonatal cardiomyocytes by homologous MEF2 transcription factors
Cody A. Desjardins et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1
Hai Dang Nguyen et al.
MOLECULAR CELL (2017)
ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response
Andrew N. Blackford et al.
MOLECULAR CELL (2017)
cGAS surveillance of micronuclei links genome instability to innate immunity
Karen J. Mackenzie et al.
NATURE (2017)
Mitotic progression following DNA damage enables pattern recognition within micronuclei
Shane M. Harding et al.
NATURE (2017)
IRF3 and type I interferons fuel a fatal response to myocardial infarction
Kevin R. King et al.
NATURE MEDICINE (2017)
The essential kinase ATR: ensuring faithful duplication of a challenging genome
Joshua C. Saldivar et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)
DNA-RNA hybrids: the risks of DNA breakage during transcription
Andres Aguilera et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner
Aleksandra Deczkowska et al.
NATURE COMMUNICATIONS (2017)
DNA-RNA hybrids: the risks of DNA breakage during transcription
Andres Aguilera et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
An ATR-dependent function for the Ddx19 RNA helicase in nuclear R-loop metabolism
Dana Hodroj et al.
EMBO JOURNAL (2017)
A cGAS-Independent STING/IRF7 Pathway Mediates the Immunogenicity of DNA Vaccines
John J. Suschak et al.
JOURNAL OF IMMUNOLOGY (2016)
Biological implications of somatic DDX41 p.R525H mutation in acute myeloid leukemia
Moe Kadono et al.
EXPERIMENTAL HEMATOLOGY (2016)
The AIM2-like Receptors Are Dispensable for the Interferon Response to Intracellular DNA
Elizabeth E. Gray et al.
IMMUNITY (2016)
Increased global transcription activity as a mechanism of replication stress in cancer
Panagiotis Kotsantis et al.
NATURE COMMUNICATIONS (2016)
Co-transcriptional R-loops are the main cause of estrogen-induced DNA damage
Caroline Townsend Stork et al.
ELIFE (2016)
DNA Damage Primes the Type I Interferon System via the Cytosolic DNA Sensor STING to Promote Anti-Microbial Innate Immunity
Anetta Hartlova et al.
IMMUNITY (2015)
Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation
Siqi Liu et al.
SCIENCE (2015)
Bruton's Tyrosine Kinase Phosphorylates DDX41 and Activates Its Binding of dsDNA and STING to Initiate Type 1 Interferon Response
Koon-Guan Lee et al.
CELL REPORTS (2015)
Aicardi-Goutieres syndrome and the type I interferonopathies
Yanick J. Crow et al.
NATURE REVIEWS IMMUNOLOGY (2015)
Simian Virus 40 Large T Antigen Induces IFN-Stimulated Genes through ATR Kinase
Adriana Forero et al.
JOURNAL OF IMMUNOLOGY (2014)
Transcription-Coupled Nucleotide Excision Repair Factors Promote R-Loop-Induced Genome Instability
Julie Sollier et al.
MOLECULAR CELL (2014)
Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool
Edward Y. Chen et al.
BMC BIOINFORMATICS (2013)
STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease
Jan Petrasek et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
DNA Damage Sensing by the ATM and ATR Kinases
Alexandre Marechal et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
Fiji: an open-source platform for biological-image analysis
Johannes Schindelin et al.
NATURE METHODS (2012)
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity
Brian J. Ferguson et al.
ELIFE (2012)
The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells
Zhiqiang Zhang et al.
NATURE IMMUNOLOGY (2011)
Transcription Factor Redundancy Ensures Induction of the Antiviral State
Sonja Schmid et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
Hiroki Ishikawa et al.
NATURE (2009)
MDA5 participates in the detection of paramyxovirus infection and is essential for the early activation of dendritic cells in response to Sendai virus defective interfering particles
Jacob S. Yount et al.
JOURNAL OF IMMUNOLOGY (2008)
Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA
Takeshi Saito et al.
NATURE (2008)
West Nile virus evades activation of interferon regulatory factor 3 through RIG-I-dependent and -independent pathways without antagonizing host defense signaling
BL Fredericksen et al.
JOURNAL OF VIROLOGY (2006)
R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells
KF Yu et al.
NATURE IMMUNOLOGY (2003)
Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor
FJ Naya et al.
NATURE MEDICINE (2002)
分享论文
