4.6 Article

An open-label pilot trial of faecal microbiome transfer to restore the gut microbiome in anorexia nervosa: protocol

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Microbiology

The gut microbiota contributes to the pathogenesis of anorexia nervosa in humans and mice

Yong Fan et al.

Summary: This study investigated the role of gut microbiota in the pathogenesis of anorexia nervosa (AN) by analyzing metagenomics and metabolomics data from AN patients and healthy females. The results showed that AN patients exhibited alterations in gut microbiota composition and function, as well as increased levels of metabolites associated with reduced food intake. Microbiota transplantation experiments further confirmed the contribution of gut microbiota to AN behavior.

NATURE MICROBIOLOGY (2023)

Article Nutrition & Dietetics

Multi-omics data integration in anorexia nervosa patients before and after weight regain: A microbiome-metabolomics investigation

Alessio Maria Monteleone et al.

Summary: This study found significant changes in the gut microbiome composition of patients with anorexia nervosa, including reduced bacterial richness and an increased Bacteroidetes-to-Firmicutes ratio. The relationships between fecal metabolites and bacterial genera showed different structures among the groups, with divergent directions in the acute phase compared to the weight-restored phase. Additionally, a majority of correlations in acutely ill patients suggested a prevalent consumption of metabolites by gut microbiome.

CLINICAL NUTRITION (2021)

Review Clinical Neurology

Anorexia nervosa and gut microbiota: A systematic review and quantitative synthesis of pooled microbiological data

Laura Di Lodovico et al.

Summary: Research indicates that alterations in gut microbiota, characterized by a decrease in butyrate-producing species and an increase in mucine-degrading species, may play a role in Anorexia Nervosa. Standardized research methods are recommended to improve comparability among studies and better identify the alterations of gut microbiota in AN.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2021)

Article Endocrinology & Metabolism

Impact of fecal microbiota transplantation with capsules on the prevention of metabolic syndrome among patients with obesity

Jessica R. Allegretti et al.

Summary: A secondary analysis of a previous pilot trial showed that fecal microbiota transplantation (FMT) may have a potential role in preventing the development of metabolic syndrome in obese patients.

HORMONES-INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM (2021)

Article Psychology, Clinical

Gut microbiota alteration in adolescent anorexia nervosa does not normalize with short-term weight restoration

Nina Schulz et al.

Summary: This study found that gut microbiota alterations in adolescent patients with AN do not normalize with weight gain. Lachnospiraceae abundance at admission predicted shorter inpatient treatment duration, which could serve as a clinical predictor and target for nutritional interventions if confirmed in larger studies.

INTERNATIONAL JOURNAL OF EATING DISORDERS (2021)

Review Psychiatry

The Gut Microbiome in Anorexia Nervosa: Friend or Foe?

Ana Ghenciulescu et al.

Summary: The human gut microbiome plays a significant role in the pathophysiology of anorexia nervosa, impacting host energy metabolism, immune function, and behavior. Microbiome-based interventions such as fecal microbiota transplants and probiotics may assist in the treatment of anorexia nervosa by targeting specific microbial taxa and their interactions with the host. Further research is needed to understand the complex causal relationships between genetic risk factors, dietary patterns, and the microbiome in the development and perpetuation of this serious disorder.

FRONTIERS IN PSYCHIATRY (2021)

Article Gastroenterology & Hepatology

The gut bacterium Extibacter muris produces secondary bile acids and influences liver physiology in gnotobiotic mice

Theresa Streidl et al.

Summary: Extibacter muris, a newly described mouse gut bacterium, produces secondary bile acids in vivo that affect the liver proteomes. It has minor effects on the Oligo-MM12 community under a high-fat diet, but does not influence body weight and other physiological parameters.

GUT MICROBES (2021)

Article Microbiology

Strain engraftment competition and functional augmentation in a multi-donor fecal microbiota transplantation trial for obesity

Brooke C. Wilson et al.

Summary: The study showed that multi-donor FMT can significantly alter the structure and function of the gut microbiome, with evidence for the existence of super-donors whose microbiomes are highly effective at engrafting in recipient gut. However, despite efforts to standardize FMT dose and origin, there was high variability in strain engraftment among FMT recipients.

MICROBIOME (2021)

Article Medicine, General & Internal

Effects of Fecal Microbiome Transfer in Adolescents With Obesity The Gut Bugs Randomized Controlled Trial

Karen S. W. Leong et al.

JAMA NETWORK OPEN (2020)

Review Endocrinology & Metabolism

The Impact of Starvation on the Microbiome and Gut-Brain Interaction in Anorexia Nervosa

Jochen Seitz et al.

FRONTIERS IN ENDOCRINOLOGY (2019)

Review Gastroenterology & Hepatology

Systematic review with meta-analysis: efficacy of faecal microbiota transplantation for the treatment of irritable bowel syndrome

Gianluca Ianiro et al.

ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2019)

Review Nutrition & Dietetics

Prevalence of eating disorders over the 2000-2018 period: a systematic literature review

Marie Galmiche et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2019)

Article Gastroenterology & Hepatology

Leaky gut: mechanisms, measurement and clinical implications in humans

Michael Camilleri

Article Computer Science, Interdisciplinary Applications

The REDCap consortium: Building an international community of software platform partners

Paul A. Harris et al.

JOURNAL OF BIOMEDICAL INFORMATICS (2019)

Article Multidisciplinary Sciences

Interplay between the human gut microbiome and host metabolism

Alessia Visconti et al.

NATURE COMMUNICATIONS (2019)

Review Cell Biology

An update on gastrointestinal disturbances in eating disorders

Larissa Hetterich et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2019)

Review Neurosciences

The gut microbiome in anorexia nervosa: relevance for nutritional rehabilitation

Anu Ruusunen et al.

PSYCHOPHARMACOLOGY (2019)

Article Biochemical Research Methods

bioBakery: a meta'omic analysis environment

Lauren J. McIver et al.

BIOINFORMATICS (2018)

Review Endocrinology & Metabolism

Role of the gut microbiota in host appetite control: bacterial growth to animal feeding behaviour

Serguei O. Fetissov

NATURE REVIEWS ENDOCRINOLOGY (2017)

Article Biochemistry & Molecular Biology

Microbial strain-level population structure and genetic diversity from metagenomes

Duy Tin Truong et al.

GENOME RESEARCH (2017)

Review Gastroenterology & Hepatology

Faecal Microbiota Transplantation for Inflammatory Bowel Disease: A Systematic Review and Meta-analysis

Sudarshan Paramsothy et al.

JOURNAL OF CROHNS & COLITIS (2017)

Review Gastroenterology & Hepatology

Fecal biomarkers in inflammatory bowel disease

Robert N. Lopez et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2017)

Article Psychology, Clinical

Elevated Plasma Concentrations of Bacterial ClpB Protein in Patients with Eating Disorders

Jonathan Breton et al.

INTERNATIONAL JOURNAL OF EATING DISORDERS (2016)

Article Multidisciplinary Sciences

Gut Dysbiosis in Patients with Anorexia Nervosa

Chihiro Morita et al.

PLOS ONE (2015)

Article Psychiatry

Royal Australian and New Zealand College of Psychiatrists Clinical practice guidelines for the treatment of eating disorders

Phillipa Hay et al.

AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY (2014)

Article Nutrition & Dietetics

Alteration of intestinal barrier function during activity-based anorexia in mice

Pierre Jesus et al.

CLINICAL NUTRITION (2014)

Article Medicine, General & Internal

Oral, Capsulized, Frozen Fecal Microbiota Transplantation for Relapsing Clostridium difficile Infection

Ilan Youngster et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2014)

Review Gastroenterology & Hepatology

Fecal Microbiota Transplantation for the Treatment of Clostridium difficile Infection A Systematic Review

Giovanni Cammarota et al.

JOURNAL OF CLINICAL GASTROENTEROLOGY (2014)

Review Neurosciences

A critique of the literature on etiology of eating disorders

Azadeh A. Rikani et al.

ANNALS OF NEUROSCIENCES (2013)

Article Psychiatry

Symptom profile of major depressive disorder in women with eating disorders

Fernando Fernandez-Aranda et al.

AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY (2007)

Article Psychiatry

Comorbidity of anxiety disorders with anorexia and bulimia nervosa

WH Kaye et al.

AMERICAN JOURNAL OF PSYCHIATRY (2004)

Article Biochemistry & Molecular Biology

Intestinal permeability is decreased in anorexia nervosa

P Monteleone et al.

MOLECULAR PSYCHIATRY (2004)

Article Health Care Sciences & Services

The PHQ-9 - Validity of a brief depression severity measure

K Kroenke et al.

JOURNAL OF GENERAL INTERNAL MEDICINE (2001)