☆ 4.7 Article

Oxidized Low-Density Lipoprotein (Ox-LDL)-Triggered Double-Lock Probe for Spatiotemporal Lipoprotein Oxidation and Atherosclerotic Plaque Imaging

ADVANCED HEALTHCARE MATERIALS (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Engineering, Environmental

GSH and H2O2 dynamic correlation in the ferroptosis pathways revealed by engineered probe in tumor and kidney injury

Yuting Wang et al.

Summary: Ferroptosis, a type of cell death caused by lipid peroxidation, is closely related to the development of tumors, ischemia-reperfusion injury, and other diseases. It involves the accumulation of reactive oxygen species and thiols, which promote or inhibit ferroptosis. Understanding the dynamic correlation between reactive oxygen species and active sulfur in these pathways is crucial for revealing the regulation mechanism of ferroptosis.

CHEMICAL ENGINEERING JOURNAL (2023)

添加到收藏夹

Article Chemistry, Multidisciplinary

Peroxynitrite/Lipid Droplet Sequence-Activated Dual-Lock Fluorescent Probes Enable Precise Intraoperative Imaging of Atherosclerotic Plaques

Mangmang Sang et al.

Summary: In this study, a dual-analyte sequentially activated logic fluorescence reporting system CNN2-B was introduced to precisely identify atherosclerotic plaques in vivo. This probe was able to detect peroxynitrite and lipid droplets, the two hallmarks of atherosclerosis, and exhibited higher selectivity and sensitivity than the commercial probe hydroxyphenyl fluorescein (HPF). Fluorescence imaging using CNN2-B clearly delineated atherosclerotic plaques in mouse models.

ACS SENSORS (2023)

添加到收藏夹

Article Chemistry, Multidisciplinary

In-Sequence High-Specificity Dual-Reporter Unlocking of Fluorescent Probe Enables the Precise Identification of Atherosclerotic Plaques

Zhuo Ye et al.

Summary: This study introduces a dual-target sequentially activated fluorescence reporting system, iSHERLOCK, for precise identification of atherosclerotic plaques. It aids clinical assessment, diagnosis, and treatment of cardiovascular diseases and overcomes the limitation of precise tissue biopsy.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2022)

添加到收藏夹

Article Multidisciplinary Sciences

Ferroptosis of tumour neutrophils causes immune suppression in cancer

Rina Kim et al.

Summary: Ferroptosis is a unique and targetable immunosuppressive mechanism in the tumor microenvironment, which can be pharmacologically modulated to limit tumor progression. It induces spontaneous death of PMN-MDSCs in the tumor microenvironment and limits the activity of human and mouse T cells.

NATURE (2022)

添加到收藏夹

Article Chemistry, Analytical

Development of novel near-infrared GFP chromophore-based fluorescent probes for imaging of amyloid-? plaque and viscosity

Yuhui Guo et al.

Summary: Alzheimer's disease is closely associated with abnormal deposition of amyloid beta peptides and plaque formation. In this study, researchers developed a fluorescent probe with improved structure to achieve high selectivity for imaging Alzheimer's plaques in the near-infrared window. The probe showed high fluorescence signal-to-noise ratio and selectivity in living animals and cells, making it an effective tool for monitoring the pathological process of Alzheimer's disease.

SENSORS AND ACTUATORS B-CHEMICAL (2022)

添加到收藏夹

Review Cell Biology

Ferroptosis: a cell death connecting oxidative stress, inflammation and cardiovascular diseases

Yi Yu et al.

Summary: Ferroptosis is a newly identified iron-dependent cell death mechanism that differs from other cell death pathways, characterized by lipid peroxidation and accumulation of redox-active iron. Studies suggest that ferroptosis plays a crucial role in various cardiovascular diseases, and targeting ferroptosis may present a novel therapeutic approach in treating these conditions.

CELL DEATH DISCOVERY (2021)

添加到收藏夹

Review Materials Science, Biomaterials

Lipid Metabolism in Ferroptosis

Zhi Lin et al.

Summary: Lipid metabolism plays a crucial role in regulating cell survival and death. Abnormal lipid metabolism can lead to ferroptosis, an iron-dependent regulated cell death. Various antioxidant systems and membrane repair pathways help mitigate oxidative damage and support cell survival, especially in pathological conditions like cancer. Impairment of the ferroptosis machinery is associated with the development of diseases such as cancer and tissue damage.

ADVANCED BIOLOGY (2021)

添加到收藏夹

Article Nanoscience & Nanotechnology

Lipid Droplet-Specific Probe for Rapidly Locating Atherosclerotic Plaques and Intraoperative Imaging via In Situ Spraying

Mangmang Sang et al.

Summary: The study introduces an aerosol spraying technique of a lipid droplet-specific probe to precisely locate atherosclerotic plaques during surgery. This method allows for stable imaging of the plaque within 5 minutes, accurately delineating the plaque margins and size, with weak interference from background signals. The intraoperative fluorescence imaging via in situ delivery of the lipid droplet-specific probe shows promise for effective clinical application.

ACS APPLIED MATERIALS & INTERFACES (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

A Solvatochromic Fluorescent Probe Reveals Polarity Heterogeneity upon Protein Aggregation in Cells

Wang Wan et al.

Summary: A new crystallization-induced emission fluorophore was developed to quantitatively investigate the polarity of aggregated proteins, providing insights into protein status based on changes in solvent polarity; The probe can be used for live cell quantification of aggregated protein polarity, revealing heterogeneity within cellular aggregates and potentially correlating to their biochemical properties and pathogenicity.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Development of Near-Infrared Nucleic Acid Mimics of Fluorescent Proteins for In Vivo Imaging of Viral RNA with Turn-On Fluorescence

Jiaheng Zhang et al.

Summary: By structurally modulating GFP-like chromophores using a specific molecular configuration, researchers have created novel fluorogenic derivatives with infrared-shifted spectra. These derivatives can be fluorescently elicited by interacting with G-quadruplex structures, leading to the creation of FP mimics with tunable emission in the near-infrared region.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Heart Disease and Stroke Statistics-2021 Update A Report From the American Heart Association

Salim S. Virani et al.

Summary: The American Heart Association, in partnership with the National Institutes of Health, publishes annual statistics on heart disease, stroke, and cardiovascular risk factors, including the impact of health behaviors and factors on cardiovascular health. The Statistical Update covers a range of clinical heart and circulatory conditions, providing data on quality of care, procedures, and economic costs. It serves as a critical resource for various stakeholders seeking the best available data on these factors and conditions.

CIRCULATION (2021)

添加到收藏夹

Article Chemistry, Applied

An innovative hypochlorite-sensing scaffold and its imaging application in vivo

Yongfei Huang et al.

Summary: In recent years, coumarin fluorescent probes have been widely used in various fields due to their excellent optical properties. This study successfully prepared two probes with high quantum yield and rapid response by introducing electron-donating group and pyrazoline ring at different positions, providing a new concept for the construction and optimization of fluorescent probes. The probe exhibited synergistic action of -OH and pyrazoline rings, effectively detecting ClO- in cells and zebrafish.

DYES AND PIGMENTS (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Twisted intramolecular charge transfer (TICT) and twists beyond TICT: from mechanisms to rational designs of bright and sensitive fluorophores

Chao Wang et al.

Summary: This review highlights the importance of the TICT mechanism in guiding the development of bright and sensitive fluorophores. It also summarizes the molecular design strategies and compares the twisted intramolecular charge shuttle (TICS) and twists during photoinduced electron transfer (PET) mechanisms. Understanding the structure-property relationships between twisted geometries and fluorescence can aid in the rational development of fluorophores involving molecular twisting in the excited state.

CHEMICAL SOCIETY REVIEWS (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Inhibition of ferroptosis alleviates atherosclerosis through attenuating lipid peroxidation and endothelial dysfunction in mouse aortic endothelial cell

Tao Bai et al.

FREE RADICAL BIOLOGY AND MEDICINE (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

AggFluor: Fluorogenic Toolbox Enables Direct Visualization of the Multi-Step Protein Aggregation Process in Live Cells

Charles H. Wolstenholme et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Endothelial dysfunction in small arteries and early signs of atherosclerosis in ApoE knockout rats

Simin Berenji Ardestani et al.

SCIENTIFIC REPORTS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

A novel carbazolyl GFP chromophore analogue: synthesis strategy and acidic pH-activatable lysosomal probe for tracing endogenous viscosity changes

Xu Zhi et al.

NEW JOURNAL OF CHEMISTRY (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Detection of atherosclerosis-related hypochlorous acid produced in foam cells with a localized endoplasmic reticulum probe

Meng-meng Zhang et al.

CHEMICAL COMMUNICATIONS (2020)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Translocator protein localises to CD11b+ macrophages in atherosclerosis

Chantal Kopecky et al.

ATHEROSCLEROSIS (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Albumin tailoring fluorescence and photothermal conversion effect of near-infrared-II fluorophore with aggregation-induced emission characteristics

Shuai Gao et al.

NATURE COMMUNICATIONS (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Ferroptosis Accompanied by •OH Generation and Cytoplasmic Viscosity Increase Revealed via Dual-Functional Fluorescence Probe

Hongyu Li et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Azulene-Derived Fluorescent Probe for Bioimaging: Detection of Reactive Oxygen and Nitrogen Species by Two-Photon Microscopy

Lloyd C. Murfin et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

H-Atom Abstraction vs Addition: Accounting for the Diverse Product Distribution in the Autoxidation of Cholesterol and Its Esters

Zosia A. M. Zielinski et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

添加到收藏夹

Article Chemistry, Physical

Revealing the switching mechanisms of an off-on-off fluorescent logic gate system

Weijie Chi et al.

PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2019)

添加到收藏夹

Article Chemistry, Organic

TICT excited states of o- and p-N,N-dimethylamino analogues of GFP chromophore

Robert Sung et al.

JOURNAL OF PHYSICAL ORGANIC CHEMISTRY (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Modulation of Fluorescent Protein Chromophores To Detect Protein Aggregation with Turn-On Fluorescence

Yu Liu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

添加到收藏夹

Article Chemistry, Analytical

Highly Selective Fluorescent Probe Based on Hydroxylation of Phenylboronic Acid Pinacol Ester for Detection of Tyrosinase in Cells

Huihui Li et al.

ANALYTICAL CHEMISTRY (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

DNA mimics of red fluorescent proteins (RFP) based on G-quadruplex-confined synthetic RFP chromophores

Guangfu Feng et al.

NUCLEIC ACIDS RESEARCH (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Two-photon AIE bio-probe with large Stokes shift for specific imaging of lipid droplets

Meijuan Jiang et al.

CHEMICAL SCIENCE (2017)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

High-resolution and accelerated multi-parametric mapping with automated characterization of vessel disease using intravascular MRI

Guan Wang et al.

JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE (2017)

添加到收藏夹

Review Biochemistry & Molecular Biology

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

Brent R. Stockwell et al.

CELL (2017)

添加到收藏夹

Review Chemistry, Multidisciplinary

Motion-induced change in emission (MICE) for developing fluorescent probes

Dongdong Su et al.

CHEMICAL SOCIETY REVIEWS (2017)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Pleiotropic Effects of Statins on the Cardiovascular System

Adam Oesterle et al.

CIRCULATION RESEARCH (2017)

添加到收藏夹

Article Biochemistry & Molecular Biology

Novel Fluorescently Labeled Peptide Compounds for Detection of Oxidized Low-Density Lipoprotein at High Specificity

Akira Sato et al.

CHEMICAL BIOLOGY & DRUG DESIGN (2014)

添加到收藏夹

Article Chemistry, Multidisciplinary

An Enhanced PET-Based Fluorescent Probe with Ultrasensitivity for Imaging Basal and Elesclomol-Induced HClO in Cancer Cells

Hao Zhu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)

添加到收藏夹

Review Medical Laboratory Technology

Foam cells in atherosclerosis

Xiao-Hua Yu et al.

CLINICA CHIMICA ACTA (2013)

添加到收藏夹

Review Cell Biology

LOX-1, OxLDL, and Atherosclerosis

Angela Pirillo et al.

MEDIATORS OF INFLAMMATION (2013)

添加到收藏夹

Article Chemistry, Multidisciplinary

Softness of Atherogenic Lipoproteins: A Comparison of Very Low Density Lipoprotein (VLDL) and Low Density Lipoprotein (LDL) Using Elastic Incoherent Neutron Scattering (EINS)

Christian Mikl et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

添加到收藏夹

Article Multidisciplinary Sciences

RNA Mimics of Green Fluorescent Protein

Jeremy S. Paige et al.

SCIENCE (2011)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Efficacy of Aggressive Lipid Controlling Therapy for Preventing Saphenous Vein Graft Disease

Mitsumasa Hata et al.

ANNALS OF THORACIC SURGERY (2009)

添加到收藏夹

Article Chemistry, Multidisciplinary

Bond selection in the photoisomerization reaction of anionic green fluorescent protein and kindling fluorescent protein chromophore models

Seth Olsen et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)

添加到收藏夹

Article Biochemistry & Molecular Biology

A fluorescent probe for the detection of myeloperoxidase activity in atherosclerosis-associated macrophages

Joanna Shepherd et al.

CHEMISTRY & BIOLOGY (2007)

添加到收藏夹

Article Chemistry, Multidisciplinary

Direct electrochemical evaluation of plasma membrane cholesterol in live mammalian cells

Dechen Jiang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)

添加到收藏夹

Article Chemistry, Multidisciplinary

Radiationless decay of red fluorescent protein chromophore models via twisted intramolecular charge-transfer states

Seth Olsen et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)

添加到收藏夹

Review Pharmacology & Pharmacy

Current diagnostic modalities for vulnerable plaque detection

Johannes A. Schaar et al.

CURRENT PHARMACEUTICAL DESIGN (2007)

添加到收藏夹

Article Food Science & Technology

Hibiscus anthocyanins-rich extract inhibited LDL oxidation and oxLDL-mediated macrophages apoptosis

Yun-Ching Chang et al.

FOOD AND CHEMICAL TOXICOLOGY (2006)

添加到收藏夹

Article Chemistry, Multidisciplinary

Recombinant HDL-like nanoparticles: A specific contrast agent for MRI of atherosclerotic plaques

JC Frias et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.