期刊
ADVANCED HEALTHCARE MATERIALS
卷 -, 期 -, 页码 -出版社
WILEY
DOI: 10.1002/adhm.202302132
关键词
biocompatibility; biodegradable alloys; bismuth-based alloys; bone repair; metallic materials
Metallic materials are widely studied for bone repair due to their biocompatibility and strength. Stainless steel and titanium are commonly used, while biodegradable options like iron, magnesium, and zinc alloys show promise. Porous tantalum and bismuth alloys are gaining attention for their bone-friendly properties. This article reviews metallic materials for bone repair, covering their properties and addressing deficiencies.
Repair of large bone defects caused by trauma or disease poses significant clinical challenges. Extensive research has focused on metallic materials for bone repair because of their favorable mechanical properties, biocompatibility, and manufacturing processes. Traditional metallic materials, such as stainless steel and titanium alloys, are widely used in clinics. Biodegradable metallic materials, such as iron, magnesium, and zinc alloys, are promising candidates for bone repair because of their ability to degrade over time. Emerging metallic materials, such as porous tantalum and bismuth alloys, have gained attention as bone implants owing to their bone affinity and multifunctionality. However, these metallic materials encounter many practical difficulties that require urgent improvement. This article systematically reviews and analyzes the metallic materials used for bone repair, providing a comprehensive overview of their morphology, mechanical properties, biocompatibility, and in vivo implantation. Furthermore, the strategies and efforts made to address the short-comings of metallic materials are summarized. Finally, the perspectives for the development of metallic materials to guide future research and advancements in clinical practice are identified. Metallic materials are widely studied for bone repair due to their biocompatibility and strength. Stainless steel and titanium are commonly used, while biodegradable options like iron, magnesium, and zinc alloys show promise. Porous tantalum and bismuth alloys are gaining attention for their bone-friendly properties. This article reviews metallic materials for bone repair, covering their properties and addressing deficiencies.image
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