4.5 Review

Single visit rabies pre-exposure prophylaxis: A literature review

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Summary: The study found that a single dose of rabies vaccine in adults as a prophylactic vaccination could effectively prime the immune system, leading to rapid development of antibodies within 7 days post-vaccination.

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Summary: Cell culture rabies vaccines, crucial for preventing human rabies, were licensed in the 1980s. WHO recommended a lengthy intramuscular vaccination regimen initially, but encouraged research on cost-effective strategies. Clinical trials supported reduced doses, shorter timelines, and the approval of intradermal administration for rabies prophylaxis.

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Rabies pre-exposure prophylaxis elicits long-lasting immunity in humans

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The Feasibility of Canine Rabies Elimination in Africa: Dispelling Doubts with Data

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Long-term anti-rabies antibody persistence following intramuscular or low-dose intradermal vaccination of young Vietnamese children

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Immunogenicity study of abbreviated rabies preexposure vaccination schedules

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Rabies - the need for a 'one medicine' approach

A. R. Fooks

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