Maternal body mass index is not associated with assisted reproductive technology outcomes

Article Obstetrics & Gynecology

Maternal body mass index is not associated with increased rates of maternal embryonic aneuploidy

Lydia M. Hughes et al.

Summary: The relationship between maternal body mass index (BMI) and embryonic aneuploidy of maternal origin was evaluated. After adjusting for confounders, BMI was not significantly associated with maternal origin embryonic aneuploidy.

FERTILITY AND STERILITY (2022)

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Article Psychology, Applied

A lifestyle intervention randomized controlled trial in obese women with infertility improved body composition among those who experienced childhood adversity

Lotte van Dammen et al.

Summary: The study found that childhood adversity can modify the effect of preconception lifestyle intervention on weight, BMI, and body fat percentage in obese infertile women. Women with more childhood adversity experiences showed more significant reductions in these outcomes following the lifestyle intervention.

STRESS AND HEALTH (2021)

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Article Obstetrics & Gynecology

Blastocyst formation is similar in obese and normal weight women: a morphokinetic study

Jose Bellver et al.

Summary: This study found no significant differences in embryo development, blastocyst formation rate, and blastocyst morphology between obese women and normal weight women undergoing IVF. This suggests that female obesity does not impact blastocyst formation and embryo morphokinetics, and the poorer IVF outcomes described for obese women may be due to deficient endometrial receptivity.

HUMAN REPRODUCTION (2021)

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Article Endocrinology & Metabolism

Association between clinical and IVF laboratory parameters and miscarriage after single euploid embryo transfers

Maria del Carmen Nogales et al.

Summary: This study found a significant association between body mass index (BMI), endometrial thickness, and the type of endometrial preparation with miscarriage rates in patients undergoing single euploid blastocyst transfer. Other studied variables did not show a significant association with miscarriage rates.

REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY (2021)

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Article Biology

Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight NCD Risk Factor Collaboration (NCD-RisC)

Maria L. C. Iurilli et al.

Summary: The study found that changes in the prevalence of underweight and obesity were mainly influenced by shifts in the distribution of BMI, with the underweight tail of the BMI distribution being left behind in East and Southeast Asia and sub-Saharan Africa. Therefore, there is a need for policies to address all forms of malnutrition.

ELIFE (2021)

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Article Obstetrics & Gynecology

Body mass index is not associated with embryo ploidy in patients undergoing in vitro fertilization with preimplantation genetic testing

Yael R. Stovezky et al.

Summary: This study found no association between body mass index and the number or proportion of aneuploid, mosaic, or euploid embryos in patients undergoing IVF with PGT-A, suggesting that excess weight may not impact reproductive outcomes through embryo ploidy status.

FERTILITY AND STERILITY (2021)

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Article Obstetrics & Gynecology

Female obesity increases the risk of miscarriage of euploid embryos

Mauro Cozzolino et al.

Summary: The study found that obese women have a higher risk of miscarriage after euploid embryo transfer compared to women with normal weight, suggesting that factors other than chromosomal abnormalities may be responsible for this outcome.

FERTILITY AND STERILITY (2021)

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Article Obstetrics & Gynecology

Assisted reproductive technology in Japan: A summary report for 2018 by the Ethics Committee of the Japan Society of Obstetrics and Gynecology

Osamu Ishihara et al.

Summary: In 2018, the total number of ART treatment cycles and live births in Japan saw an increase from the previous year. Over 80% of cases involved single embryo transfer (SET), and there was a continuous shift from using fresh embryos to frozen-thawed embryos for embryo transfer compared to previous years.

REPRODUCTIVE MEDICINE AND BIOLOGY (2021)

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Article Obstetrics & Gynecology