4.7 Article

Discovering the Individualized Factors Associated with Sarcopenia and Sarcopenic Obesity Phenotypes-A Machine Learning Approach

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Nutrition & Dietetics

Sarcopenic obesity research perspectives outlined by the sarcopenic obesity global leadership initiative (SOGLI)- Proceedings from the SOGLI consortium meeting in rome November 2022

Gianluca Gortan Cappellari et al.

Summary: The European Society for Clinical Nutrition and Metabolism (ESPEN) and the European Association for the Study of Obesity (EASO) launched the Sarcopenic Obesity Global Leadership Initiative (SOGLI) to reach expert consensus on a definition and diagnostic criteria for Sarcopenic Obesity (SO). The present paper describes the proceeding of the Sarcopenic Obesity Global Leadership Initiative (SOGLI) meeting that was held on November 25th and 26th, 2022 in Rome, Italy. This consortium involved the participation of 50 researchers from different geographic regions and countries. The document outlines an agenda advocated by the SOGLI expert panel regarding the pathophysiology, screening, diagnosis, staging, and treatment of SO that needs to be prioritized for future research in the field.

CLINICAL NUTRITION (2023)

Review Geriatrics & Gerontology

Prevalence and risk factors of osteosarcopenia: a systematic review and meta-analysis

Tianjin Huang et al.

Summary: Osteosarcopenia is a syndrome characterized by the concurrent presence of sarcopenia and osteopenia/osteoporosis, which increases the risk of frailty, falls, fractures, hospitalization, and death. This study aimed to review the prevalence and risk factors of osteosarcopenia to provide important references for clinical work.

BMC GERIATRICS (2023)

Article Biochemistry & Molecular Biology

A Machine-Learning Approach to Target Clinical and Biological Features Associated with Sarcopenia: Findings from Northern and Southern Italian Aging Populations

Roberta Zupo et al.

Summary: Further research is needed to identify better clinical markers for sarcopenia in late life. A study using a machine-learning approach showed that SMI, HGS, FFM of legs and arms, and sex were associated with sarcopenia. Albumin, CRP, folate, and age were found to be highly predictive of sarcopenia in the whole dataset, while sex, folate, and vitamin D were the most relevant according to logistic regression analysis.

METABOLITES (2023)

Article Geriatrics & Gerontology

Preventing Osteoporosis, Sarcopenia and Obesity to Care about Quality of Life

Stefano Cacciatore et al.

Summary: A recent review analyzed the prevalence and impact of sarcopenic obesity on quality of life and physical health. Osteosarcopenic obesity, the concomitant presence of osteoporosis, sarcopenia, and obesity, has negative outcomes on morbidity, mortality, and quality of life. Timely diagnosis, prevention, and pro-health education are crucial for improving the lives of individuals with these conditions. Education and prevention, focusing on physical activity, a balanced diet, and lifestyle changes, play a significant role in long-term health and sustainable healthcare.

ANNALS OF GERIATRIC MEDICINE AND RESEARCH (2023)

Review Endocrinology & Metabolism

Global prevalence of osteosarcopenic obesity amongst middle aged and older adults: a systematic review and meta-analysis

Ying Liu et al.

Summary: The purpose of this review was to determine the global prevalence of osteosarcopenic obesity syndrome (OSO) in middle-aged and older adults. The results showed that the overall prevalence of OSO in this population was 8%, with higher rates among females and studies focusing on the elderly. This highlights the commonness of OSO and the need for diagnostic and intervention strategies in high-risk settings.

ARCHIVES OF OSTEOPOROSIS (2023)

Article Endocrinology & Metabolism

Definition and Diagnostic Criteria for Sarcopenic Obesity: ESPEN and EASO Consensus Statement

Lorenzo M. Donini et al.

Summary: Loss of skeletal muscle mass and function is common in individuals with obesity. The co-existence of excess adiposity and low muscle mass/function, known as sarcopenic obesity (SO), negatively impacts patient outcomes. However, the lack of a universally established definition and diagnostic criteria for SO hampers prevention and treatment efforts.

OBESITY FACTS (2022)

Correction Public, Environmental & Occupational Health

The lower basal metabolic rate is associated with increased risk of osteosarcopenia in postmenopausal women (vol 22, 171, 2022)

Zhila Maghbooli et al.

BMC WOMENS HEALTH (2022)

Review Geriatrics & Gerontology

Prevalence of Sarcopenic Obesity in Various Comorbidities, Diagnostic Markers, and Therapeutic Approaches: A Review

Mangalam Kumari et al.

Summary: Sarcopenic obesity, the coexistence of sarcopenia and obesity, is prevalent among the elderly population. Non-invasive diagnostic techniques can be used to evaluate this condition. Early diagnosis and treatment are crucial for preventing debilitating effects and providing high-quality care.

ANNALS OF GERIATRIC MEDICINE AND RESEARCH (2022)

Article Nutrition & Dietetics

Sex-Specific Associations between Serum Ferritin and Osteosarcopenic Obesity in Adults Aged over 50 Years

Sung-Joon Chung et al.

Summary: This study investigated the association between ferritin and adverse body composition in adults aged over 50 years. The results showed that high ferritin levels were associated with an increased risk of osteosarcopenic obesity in women, suggesting its potential use for detecting this condition.

NUTRIENTS (2022)

Review Medicine, General & Internal

Relationship between Testosterone and Sarcopenia in Older-Adult Men: A Narrative Review

Kazuyoshi Shigehara et al.

Summary: The decline in testosterone is associated with sarcopenia and frailty, and testosterone replacement therapy has been shown to improve muscle mass and strength.

JOURNAL OF CLINICAL MEDICINE (2022)

Review Rheumatology

Sarcopenia and bone health: new acquisitions for a firm liaison

Umberto Tarantino et al.

Summary: Osteosarcopenia is a condition characterized by the simultaneous presence of osteopenia/osteoporosis and sarcopenia, and it is caused by dysfunctions in the bone-muscle unit. While there are still gaps in our understanding of the underlying mechanisms, exercise and nutrition interventions have been found to be essential in combating osteosarcopenia.

THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE (2022)

Article Geriatrics & Gerontology

How does adipose tissue contribute to inflammageing?

Mauro Zamboni et al.

Summary: As individuals age, white adipose tissue undergoes significant changes, becoming dysfunctional and potentially leading to a systemic pro-inflammatory state, contributing to age-related metabolic alterations.

EXPERIMENTAL GERONTOLOGY (2021)

Review Rheumatology

Osteosarcopenia: where osteoporosis and sarcopenia collide

Michael A. Clynes et al.

Summary: The coexistence of osteoporosis and sarcopenia, termed 'osteosarcopenia', is expected to increase significantly with an aging population, leading to increased personal and societal burden. Individuals with both conditions may face a greater risk of falls, fractures, institutionalization and mortality, with multifactorial etiology involving genetics, age, inflammation and obesity. Potential therapeutic agents targeting both muscle and bone are being developed, outlined in this review.

RHEUMATOLOGY (2021)

Review Nutrition & Dietetics

Related Factors and Clinical Outcomes of Osteosarcopenia: A Narrative Review

Tatsuro Inoue et al.

Summary: Osteosarcopenia is a common geriatric condition that predominantly affects women, and is associated with increased risks of death, fractures, and falls. However, the causal relationship between osteosarcopenia and these outcomes remains unclear, highlighting the need for further longitudinal and interventional studies to fully understand this syndrome.

NUTRIENTS (2021)

Article Endocrinology & Metabolism

Reference Values for DXA-Derived Visceral Adipose Tissue in Adults 40 Years and Older from a European Population: The Tromso Study 2015-2016

Marie W. Lundblad et al.

Summary: This study aimed to develop reference values for VAT for women and men, and investigate the associations between VAT and cardiometabolic risk factors using different measurement units. The results showed that VAT was similarly associated with cardiometabolic risk factors across various measurement units.

JOURNAL OF OBESITY (2021)

Article Geriatrics & Gerontology

Osteosarcopenic Obesity Associated with Poor Physical Performance in the Elderly Chinese Community

Yixuan Ma et al.

CLINICAL INTERVENTIONS IN AGING (2020)

Article Geriatrics & Gerontology

Osteosarcopenia among postmenopausal women and handgrip strength as a practical method for predicting the risk

Buliana Hamad et al.

AGING CLINICAL AND EXPERIMENTAL RESEARCH (2020)

Article Geriatrics & Gerontology

Sarcopenia: revised European consensus on definition and diagnosis

Alfonso J. Cruz-Jentoft et al.

AGE AND AGEING (2019)

Article Geriatrics & Gerontology

Association of serum vitamin D with osteosarcopenic obesity: Korea National Health and Nutrition Examination Survey 2008-2010

Jinhee Kim et al.

JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE (2017)

Review Endocrinology & Metabolism

Osteosarcopenia: where bone, muscle, and fat collide

H. P. Hirschfeld et al.

OSTEOPOROSIS INTERNATIONAL (2017)

Article Geriatrics & Gerontology

The Old and the Oldest-old: Do They Have Different Perspectives on Adjustment to Aging?

Sofia von Humboldt et al.

INTERNATIONAL JOURNAL OF GERONTOLOGY (2015)