☆ 4.7 Article

Adipose Tissue Protects against Hepatic Steatosis in Male Rats Fed a High-Fat Diet plus Liquid Fructose: Sex-Related Differences

NUTRIENTS (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Review Gastroenterology & Hepatology

An adipocentric perspective on the development and progression of non-alcoholic fatty liver disease

Eunyoung Lee et al.

Summary: The liver and white adipose tissue play critical roles in regulating systemic energy balance. While they can adapt to energy surplus to a certain extent, excessive accumulation of fat in adipose tissue can lead to metabolic disturbances and inflammation. This can result in liver overload and the development of diseases such as non-alcoholic fatty liver.

JOURNAL OF HEPATOLOGY (2023)

添加到收藏夹

Article Food Science & Technology

ChREBP-driven DNL and PNPLA3 Expression Induced by Liquid Fructose are Essential in the Production of Fatty Liver and Hypertriglyceridemia in a High-Fat Diet-Fed Rat Model

Ana Magdalena Velazquez et al.

Summary: This study aims to determine the role of dietary saturated fatty acids (FA) versus liquid fructose in the development of fatty liver and hypertriglyceridemia. The results show that adding liquid fructose to the diet plays a decisive role in the accumulation of liver fat and production of high triglycerides, through increased de novo lipogenesis and reduced fatty acid catabolism.

MOLECULAR NUTRITION & FOOD RESEARCH (2022)

添加到收藏夹

Review Endocrinology & Metabolism

The Regulation of Adipose Tissue Health by Estrogens

Benjamin M. Steiner et al.

Summary: Obesity and its associated metabolic diseases are significant health problems. The uncontrolled expansion of white adipose tissue is a major driver for these conditions. The sex steroid estrogen plays a critical role in body fat distribution and adipose tissue health.

FRONTIERS IN ENDOCRINOLOGY (2022)

添加到收藏夹

Article Cell Biology

ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activity

Anne Fougerat et al.

Summary: In hepatocytes, PPAR alpha is important for maintaining homeostasis during fasting, and the absence of ATGL in adipocytes impairs the production of ketone bodies and FGF21 during fasting. Liver gene expression analysis reveals that these fasting-induced genes are sensitive to both ATGL deletion in adipocytes and PPAR alpha deletion in hepatocytes. Activation of the beta(3)-adrenergic receptor induces PPAR alpha-dependent responses not only in the liver but also in BAT. Intact PPAR alpha activity in hepatocytes is necessary for the interplay between adipose tissues and the liver during fat mobilization.

CELL REPORTS (2022)

添加到收藏夹

Review Gastroenterology & Hepatology

Clinical impact of sexual dimorphism in non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH)

Patrizia Burra et al.

Summary: NAFLD/NASH is a sex-dimorphic disease, with a higher prevalence in men. Factors such as sexual category, sex hormones, and gender habits interact with numerous NAFLD factors, altering risk profiles and phenotypes. A better understanding of sex differences in NAFLD could lead to personalized therapies.

LIVER INTERNATIONAL (2021)

添加到收藏夹

Review Endocrinology & Metabolism

Hepatic sexual dimorphism - implications for non-alcoholic fatty liver disease

Philippe Lefebvre et al.

Summary: The liver, often seen as a single functional unit, is in fact highly complex and adaptable. Sexual dimorphism in liver function is frequently overlooked in the context of NAFLD, but understanding this aspect could lead to improved insights into the disease's pathogenesis.

NATURE REVIEWS ENDOCRINOLOGY (2021)

添加到收藏夹

Review Endocrinology & Metabolism

Lipolysis: cellular mechanisms for lipid mobilization from fat stores

Gernot F. Grabner et al.

Summary: This review discusses the significant revisions in the understanding of intracellular lipolysis over the past two decades, focusing on how it affects lipid-mediated signaling, metabolic regulation, and energy homeostasis in multiple organs. The review also explores how these processes impact disease pathogenesis and how targeting lipolysis could potentially prevent or treat various diseases.

NATURE METABOLISM (2021)

添加到收藏夹

Review Gastroenterology & Hepatology

Global epidemiology of lean non-alcoholic fatty liver disease: A systematic review and meta-analysis

Feng-Bin Lu et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2020)

添加到收藏夹

Review Surgery

Adipose Morphology: a Critical Factor in Regulation of Human Metabolic Diseases and Adipose Tissue Dysfunction

Fangcen Liu et al.

OBESITY SURGERY (2020)

添加到收藏夹

Article Nutrition & Dietetics

Effects of a Low Dose of Caffeine Alone or as Part of a Green Coffee Extract, in a Rat Dietary Model of Lean Non-Alcoholic Fatty Liver Disease without Inflammation

Ana Magdalena Velazquez et al.

NUTRIENTS (2020)

添加到收藏夹

Review Gastroenterology & Hepatology

Prevalence and Profile of Nonalcoholic Fatty Liver Disease in Lean Adults: Systematic Review and Meta-Analysis

Steven Young et al.

HEPATOLOGY COMMUNICATIONS (2020)

添加到收藏夹

Review Gastroenterology & Hepatology

Sex Differences in Nonalcoholic Fatty Liver Disease: State of the Art and Identification of Research Gaps

Amedeo Lonardo et al.

HEPATOLOGY (2019)

添加到收藏夹

Article Cell Biology

Exercise Alleviates Obesity-Induced Metabolic Dysfunction via Enhancing FGF21 Sensitivity in Adipose Tissues

Leiluo Geng et al.

CELL REPORTS (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Brain leptin reduces liver lipids by increasing hepatic triglyceride secretion and lowering lipogenesis

Martina Theresa Hackl et al.

NATURE COMMUNICATIONS (2019)

添加到收藏夹

Review Biochemistry & Molecular Biology

Fibroblast Growth Factor 21 and the Adaptive Response to Nutritional Challenges

Ursula Martinez-Garza et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

添加到收藏夹

Review Endocrinology & Metabolism

Metabolic adaptation and maladaptation in adipose tissue

Edward T. Chouchani et al.

NATURE METABOLISM (2019)

添加到收藏夹

Article Food Science & Technology

Chronic Liquid Fructose, but not Glucose, Supplementation Selectively Induces Visceral Adipose Tissue Leptin Resistance and Hypertrophy in Female Sprague-Dawley Rats

Gemma Sanguesa et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2018)

添加到收藏夹

Article Endocrinology & Metabolism

FGF21 resistance is not mediated by downregulation of beta-klotho expression in white adipose tissue

Kathleen R. Markan et al.

MOLECULAR METABOLISM (2017)

添加到收藏夹

Article Endocrinology & Metabolism

High-fat diet-induced obesity Rat model: a comparison between Wistar and Sprague-Dawley Rat

Claudia Marques et al.

ADIPOCYTE (2016)

添加到收藏夹

Article Medicine, Research & Experimental

ChREBP regulates fructose-induced glucose production independently of insulin signaling

Mi-Sung Kim et al.

JOURNAL OF CLINICAL INVESTIGATION (2016)

添加到收藏夹

Article Gastroenterology & Hepatology

Gender-Specific Differences in Adipose Distribution and Adipocytokines Influence Adolescent Nonalcoholic Fatty Liver Disease

Oyekoya T. Ayonrinde et al.

HEPATOLOGY (2011)

添加到收藏夹

Article Endocrinology & Metabolism

Concerted action of leptin in regulation of fatty acid oxidation in skeletal muscle and liver

S. Wein et al.

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES (2007)

添加到收藏夹

Article Endocrinology & Metabolism

PPARα mediates the hypolipidemic action of fibrates by antagonizing FoxO1

Shen Qu et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2007)

添加到收藏夹

Article Gastroenterology & Hepatology

Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity

JD Browning et al.

HEPATOLOGY (2004)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.