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BIOCHEMICAL PHARMACOLOGY (2021)
Melittin inhibits the expression of key genes involved in tumor microenvironment formation by suppressing HIF-1α signaling in breast cancer cells
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BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2021)
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Melittin suppresses growth and induces apoptosis of non-small-cell lung cancer cells via down-regulation of TGF-β-mediated ERK signal pathway
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BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH (2021)
TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells
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ONCOLOGY LETTERS (2021)
Graphene oxide-based magnetic nanocomposites for the delivery of melittin to cervical cancer HeLa cells
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NANOTECHNOLOGY (2020)
Apoptotic Effects of Melittin on 4T1 Breast Cancer Cell Line is associated with Up Regulation of Mfn1 and Drp1 mRNA Expression
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ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2020)
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BIOMOLECULES (2020)
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TOXINS (2020)
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ANTIBIOTICS-BASEL (2020)
Honeybee venom and melittin suppress growth factor receptor activation in HER2-enriched and triple-negative breast cancer
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NPJ PRECISION ONCOLOGY (2020)
Bee venom inhibits the proliferation and migration of cervical-cancer cells in an HPV E6/E7-dependent manner
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BMB REPORTS (2020)
Anti-Tumor Effects of Melittin and Its Potential Applications in Clinic
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CURRENT PROTEIN & PEPTIDE SCIENCE (2019)
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APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2019)
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JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019)
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CANCERS (2019)
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PLOS ONE (2019)
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DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2019)
Helical Structure of Recombinant Melittin
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JOURNAL OF PHYSICAL CHEMISTRY B (2019)
Apoptotic Effect of Melittin Purified from Iranian Honey Bee Venom on Human Cervical Cancer HeLa Cell Line
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INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS (2018)
Targeted delivery of melittin to cancer cells by AS1411 anti-nucleolin aptamer
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DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2018)
MEL-pep, an analog of melittin, disrupts cell membranes and reverses 5-fluorouracil resistance in human hepatocellular carcinoma cells
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INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2018)
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ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY (2018)
Melittin inhibits the invasion of MCF-7 cells by downregulating CD147 and MMP-9 expression
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ONCOLOGY LETTERS (2017)
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EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2017)
A novel melittin nano-liposome exerted excellent anti-hepatocellular carcinoma efficacy with better biological safety
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JOURNAL OF HEMATOLOGY & ONCOLOGY (2017)
Melittin exerts an antitumor effect on non-small cell lung cancer cells
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MOLECULAR MEDICINE REPORTS (2017)
Melittin suppresses tumor progression by regulating tumor-associated macrophages in a Lewis lung carcinoma mouse model
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ONCOTARGET (2017)
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ACS MACRO LETTERS (2017)
Melittin inhibits tumor growth and decreases resistance to gemcitabine by downregulating cholesterol pathway gene CLU in pancreatic ductal adenocarcinoma
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CANCER LETTERS (2017)
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JOURNAL OF TRANSLATIONAL MEDICINE (2016)
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Preparation and Characterization of Gelonin-Melittin Fusion Biotoxin for Synergistically Enhanced Anti-Tumor Activity
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PHARMACEUTICAL RESEARCH (2016)
Melittin induces human gastric cancer cell apoptosis via activation of mitochondrial pathway
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WORLD JOURNAL OF GASTROENTEROLOGY (2016)
First report on the isolation of melittin from Iranian honey bee venom and evaluation of its toxicity on gastric cancer AGS cells
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JOURNAL OF THE CHINESE MEDICAL ASSOCIATION (2015)
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TOXICOLOGY AND APPLIED PHARMACOLOGY (2015)
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JOURNAL OF MATERIALS CHEMISTRY B (2015)
Expression and anticancer activity analysis of recombinant human uPA1-43-melittin
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INTERNATIONAL JOURNAL OF ONCOLOGY (2015)
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ASIAN PACIFIC JOURNAL OF CANCER PREVENTION (2014)
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CHINESE JOURNAL OF INTEGRATIVE MEDICINE (2014)
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FOOD AND CHEMICAL TOXICOLOGY (2014)
Inhibitory Effect of Biosynthetic Nanoscale Peptide Melittin on Hepatocellular Carcinoma, Driven by Survivin Promoter
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JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2014)
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PEPTIDES (2014)
Melittin Restores PTEN Expression by Down-Regulating HDAC2 in Human Hepatocelluar Carcinoma HepG2 Cells
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PLOS ONE (2014)
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PROTEIN EXPRESSION AND PURIFICATION (2014)
Melittin enhances radiosensitivity of hypoxic head and neck squamous cell carcinoma by suppressing HIF-1α
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TUMOR BIOLOGY (2014)
Hybrid Melittin Cytolytic Peptide-Driven Ultrasmall Lipid Nanoparticles Block Melanoma Growth in Vivo
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ACS NANO (2013)
Construction and expression of sTRAIL-melittin combining enhanced anticancer activity with antibacterial activity in Escherichia coli
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APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2013)
A novel melittin-MhIL-2 fusion protein inhibits the growth of human ovarian cancer SKOV3 cells in vitro and in vivo tumor growth
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CANCER IMMUNOLOGY IMMUNOTHERAPY (2013)
Construction and Characterization of a CTLA-4-Targeted scFv-Melittin Fusion Protein as a Potential Immunosuppressive Agent for Organ Transplant
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CELL BIOCHEMISTRY AND BIOPHYSICS (2013)
Enhanced binding to and killing of hepatocellular carcinoma cells in vitro by melittin when linked with a novel targeting peptide screened from phage display
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JOURNAL OF PEPTIDE SCIENCE (2013)
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TOXIN REVIEWS (2013)
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TOXICOLOGY AND APPLIED PHARMACOLOGY (2012)
Anti-Cancer Effect of Bee Venom in Prostate Cancer Cells Through Activation of Caspase Pathway Via Inactivation of NF-κB
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PROSTATE (2011)
Selective death of human breast cancer cells by lytic immunoliposomes: Correlation with their HER2 expression level
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CANCER LETTERS (2010)
Molecularly targeted nanocarriers deliver the cytolytic peptide melittin specifically to tumor cells in mice, reducing tumor growth
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JOURNAL OF CLINICAL INVESTIGATION (2009)
Melittin exhibits necrotic cytotoxicity in gastrointestinal cells which is attenuated by cholesterol
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BIOCHEMICAL PHARMACOLOGY (2008)
Melittin prevents liver cancer cell metastasis through inhibition of the Rac1-dependent pathway
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HEPATOLOGY (2008)
Growth arrest and apoptosis of the human hepatocellular carcinoma cell line Bel-7402 induced by melittin
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ONKOLOGIE (2006)
Inhibitory effect of recombinant adenovirus carrying melittin gene on hepatocellular carcinoma
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ANNALS OF ONCOLOGY (2005)
Cytotoxic properties of immunoconjugates containing melittin-like peptide 101 against prostate cancer: in vitro and in vivo studies
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CANCER IMMUNOLOGY IMMUNOTHERAPY (2004)