期刊
MYCOSES
卷 59, 期 10, 页码 662-667出版社
WILEY
DOI: 10.1111/myc.12523
关键词
Fonsecaea nubica; chromoblastomycosis; auricle; internal transcribed spacer rDNA
资金
- National Science Foundation of China [81401650, 81260236]
- Young Teacher Foundation of Sun Yat-sen University [13ykpy32]
A first auricular case of chromoblastomycosis due to Fonsecaea nubica is reported in a 42-year-old Chinese male. He presented a slightly verrucous, erythematous plaque on his right auricle which had gradually extended over a 10-year period, and the patient reported a history of dog flea sting before onset of the lesions. Diagnosis was based on histopathological and mycological examination of clinical samples, which revealed muriform cells. Identification of the aetiological agent was assessed by morphological characteristics and confirmed at species level by sequencing of the rDNA internal transcribed spacer (ITS). The patient showed marked clinical improvement after 3 months combination therapy with itraconazole and terbinafine. The possible mode of transmission of auricular chromoblastomycosis is discussed.
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