期刊
BEILSTEIN JOURNAL OF NANOTECHNOLOGY
卷 14, 期 -, 页码 857-864出版社
BEILSTEIN-INSTITUT
DOI: 10.3762/bjnano.14.70
关键词
3D printing; microfabrication; microneedles; personalized medicine; transdermal drug delivery; two-photon polymerization
Microneedles and microneedle arrays are emerging miniaturized medical devices for painless transdermal drug delivery. New additive manufacturing methods enable novel microneedle designs for clinical trial assessments. However, current literature reviews suggest a lack of personalized designs for transdermal drug delivery. In this perspective article, we review current microneedle designs, microfabrication methods, and propose personalized microneedles for patient-centric care.
Microneedles and, subsequently, microneedle arrays are emerging miniaturized medical devices for painless transdermal drug delivery. New and improved additive manufacturing methods enable novel microneedle designs to be realized for preclinical and clinical trial assessments. However, current literature reviews suggest that industrial manufacturers and researchers have focused their efforts on one-size-fits-all designs for transdermal drug delivery, regardless of patient demographic and injection site. In this perspective article, we briefly review current microneedle designs, microfabrication methods, and industrialization strategies. We also provide an outlook where microneedles may become personalized according to a patient's demographic in order to increase drug delivery efficiency and reduce healing times for patient-centric care.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据