Ligand-Metal Cooperation Enables Net Ring-Opening C-C Activation/Difunctionalization of Cyclopropyl Ketones

Article Chemistry, Multidisciplinary

Radical Carbonyl Umpolung Arylation via Dual Nickel Catalysis

Huan-Ming Huang et al.

Summary: This study discloses a reverse strategy to achieve radical carbonyl arylation via dual catalysis, which can construct complex organic compounds without the need for pre-functionalization.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2022)

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Article Chemistry, Physical

Nickel-Catalyzed Defluorinative Coupling of Aliphatic Aldehydes with Trifluoromethyl Alkenes

Jichao Xiao et al.

Summary: A simple procedure for the nickel-catalyzed defluorinative alkylation of unactivated aliphatic aldehydes is reported. The protocol exhibits broad substrate scope, mild conditions, and a simple catalytic setup.

ACS CATALYSIS (2022)

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Article Chemistry, Multidisciplinary

Stereoinvertive Nucleophilic Substitution at Quaternary Carbon Stereocenters of Cyclopropyl Ketones and Ethers

Xu Chen et al.

Summary: A highly selective nucleophilic substitution reaction has been developed for the quaternary carbon stereocenter of cyclopropyl ketones and cyclopropyl carbinol derivatives, utilizing TMSBr, DMPSCl, and TMSN3 as nucleophiles. The reaction proceeds in a stereoinvertive manner at the most substituted quaternary carbon center, potentially due to the presence of a bicyclobutonium species.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2022)

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Article Chemistry, Multidisciplinary

Catalysis with Diboron(4)/Pyridine: Application to the Broad-Scope[3+2] Cycloaddition of Cyclopropanes and Alkenes

Zhengwei Ding et al.

Summary: This study reports an economical reaction using commercial diboron(4) as a catalyst. By designing a catalytic cycle and using a pyridine cocatalyst, boronyl radicals can be generated and transferred reversibly. The reaction features metal-free conditions, inexpensive and stable catalysts, simple operation, and a broad substrate scope compared to transition metal-based catalysts.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2022)

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Article Chemistry, Organic

Nickel-Catalyzed Reductive Coupling of γ-Metalated Ketones with Unactivated Alkyl Bromides

Ning Cui et al.

Summary: A nickel-catalyzed reductive cross-coupling reaction has been developed for the synthesis of aryl alkyl ketones from aryl cyclopropyl ketones and unactivated alkyl bromides. The reaction proceeds via radical cleavage of the alkyl bromide, and provides access to a variety of gamma-alkyl-substituted ketones through ring opening of cyclopropyl ketones (26 examples, 50-90% yield).

ORGANIC LETTERS (2022)

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Article Chemistry, Physical

Nickel-Catalyzed Regioselective Reductive Ring Opening of Aryl Cyclopropyl Ketones with Alkyl Bromides

Bing Yuan et al.

Summary: In this study, we have successfully implemented a reductive strategy for the ring opening reaction of aryl cyclopropylketones with unactivated alkyl bromides. The nickel-catalyzed reductive Csp3-Csp3cross-coupling reaction proceeds with complete regioselectivity, bypassing the need for pregenerated organometallics and allowing for efficient synthesis of alkylated ketones with high step economy and functionality tolerance.

ACS CATALYSIS (2022)

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Article Chemistry, Organic

Homogeneous Organic Electron Donors in Nickel-Catalyzed Reductive Transformations

David J. Charboneau et al.

Summary: This article summarizes the recent progress in the use of homogeneous organic electron donors in Ni-catalyzed cross-electrophile coupling reactions and discusses their advantages and limitations in synthetic chemistry. The discussion of the strengths and weaknesses of different methods for introducing electrons is also applicable to other reductive transformations.

JOURNAL OF ORGANIC CHEMISTRY (2022)

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Review Chemistry, Multidisciplinary

Selective Carbon-Carbon Bond Cleavage of Cyclopropylamine Derivatives

Olga O. Sokolova et al.

Summary: This review summarizes synthetic developments reported from 1987 to 2019 that exploit C-C single bond cleavage of cyclopropylamine-based systems. The synthetic and mechanistic aspects of key methodologies are highlighted, and examples where aminocyclopropanes are exploited as key intermediates in multistep synthesis are also discussed. The review encompasses cases where aminocyclopropanes participate in polar reactions, pericyclic processes, radical-based reactions, and C-C bond activations.

CHEMICAL REVIEWS (2021)

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Review Chemistry, Multidisciplinary

Creating Stereocenters within Acyclic Systems by C-C Bond Cleavage of Cyclopropanes

Yair Cohen et al.

Summary: Recent advancements in the stereoselective synthesis of polysubstituted cyclopropanes have enabled chemists to access these strained rings with high diastereomeric and enantiomeric ratios. This development has led to a paradigm shift in the synthesis of stereodefined acyclic molecules through selective carbon-carbon bond cleavage. Application of these concepts has been demonstrated in the total syntheses of various natural products and important molecules, highlighting the power of these strategies in organic synthesis.

CHEMICAL REVIEWS (2021)

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Article Chemistry, Multidisciplinary

A Diverse Library of Chiral Cyclopropane Scaffolds via Chemoenzymatic Assembly and Diversification of Cyclopropyl Ketones

Donggeon Nam et al.

Summary: This study presents a chemoenzymatic strategy for the stereoselective assembly and diversification of cyclopropyl ketones, a versatile class of functionalized cyclopropanes. By utilizing an engineered variant of sperm whale myoglobin, highly diastereo- and enantioselective construction of these molecules is achieved via olefin cyclopropanation in the presence of a diazoketone carbene donor reagent. The resulting enzymatic products can be further transformed to yield a collection of structurally diverse cyclopropane-containing scaffolds in optically pure form, demonstrating the potential of chemoenzymatic synthesis for medicinal chemistry and drug discovery.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

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Article Chemistry, Multidisciplinary

Recent Advances in Photoredox‐Mediated Radical Conjugate Addition Reactions: An Expanding Toolkit for the Giese Reaction

Anastasia L. Gant Kanegusuku et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

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Article Chemistry, Multidisciplinary

Three-Component Coupling of Acyl Fluorides, Silyl Enol Ethers, and Alkynes by P(III)/P(V) Catalysis

Hayato Fujimoto et al.

Summary: The phosphine-catalyzed hydrovinylation reaction involves a three-component coupling of acyl fluorides, silyl enol ethers, and alkynoates. The success of the reaction is attributed to the formal transmetalation between pentacoordinate P(V) species and a silyl enol ether, enabling C-C bond formation between polarity-mismatched sites. This bond formation, not achievable by transition metal catalysis, is achieved through a P(III)/P(V) manifold.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

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Article Chemistry, Multidisciplinary

Tunable and Practical Homogeneous Organic Reductants for Cross-Electrophile Coupling

David J. Charboneau et al.

Summary: A series of new tunable homogeneous organic reductants based on a tetraaminoethylene scaffold have been synthesized, which exhibit enhanced air stability and solid state properties at room temperature. These reductants show significantly milder reduction potential than conventional reductants, allowing for controlled alkyl radical generation in Ni-catalyzed XEC reactions. The new reductants are expected to replace current homogeneous reductants due to their stability and lead to the development of novel synthetic methods.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

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Article Chemistry, Multidisciplinary

Nickel-Catalyzed Decarboxylative Coupling of Redox-Active Esters with Aliphatic Aldehydes

Jichao Xiao et al.

Summary: This study demonstrates a method using nickel catalysis and BiOx ligand for the reductive coupling of redox-active esters with aliphatic aldehydes to obtain silyl-protected secondary alcohols. The protocol is simple, mild, and tolerates a variety of functional groups, with potential mechanistic insights pointing towards a radical chain pathway.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

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Article Chemistry, Organic

Soft Enolization of 3-Substituted Cycloalkanones Exhibits Significantly Improved Regiocontrol vs Hard Enolization Conditions

Natalie C. Dwulet et al.

Summary: Soft enolization conditions are shown to be more efficient than hard enolization protocols in regioselectively forming enoxysilanes from unsymmetrical 3-substituted cycloalkanones. The regioselectivities achieved are complementary to those obtained from cycloalkenone conjugate addition/enolate silylation with high selectivity.

ORGANIC LETTERS (2021)

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Article Chemistry, Multidisciplinary

Enantioselective α-Arylation of Ketones via a Novel Cu(I)-Bis(phosphine) Dioxide Catalytic System

Margarita Escudero-Casao et al.

Summary: A novel catalytic system based on copper(I) and chiral bis(phosphine) dioxides has been developed for the arylation of silyl enol ethers, yielding enolizable alpha-arylated ketones with high yields and enantiomeric excess up to 95%. This method is applicable to noncyclic ketones and complements other palladium-catalyzed approaches. Optimization of ligand structure was achieved through rational design driven by correlation analysis, and preliminary mechanistic hypotheses were evaluated to understand the role of chiral bis(phosphine) dioxides.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

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Article Chemistry, Multidisciplinary

SmI2-Catalyzed Intermolecular Coupling of Cyclopropyl Ketones and Alkynes: A Link between Ketone Conformation and Reactivity

Soumitra Agasti et al.

Summary: Samarium(II) diiodide (SmI2) is a crucial reductant in organic synthesis, but often requires superstoichiometric amounts leading to cost and waste issues. Recent research has shown that using catalytic amounts of SmI2 can achieve radical coupling reactions without the need for superstoichiometric metal coreductants.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

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Article Chemistry, Multidisciplinary

Controlled Single-Electron Transfer via Metal-Ligand Cooperativity Drives Divergent Nickel-Electrocatalyzed Radical Pathways

Anna Wuttig et al.

Summary: Electrocatalysis using Ni-ligand cooperativity can control electron transfer, selectively activating alkyl iodides via outer-sphere electron transfer, while indiscriminately activating both substrates and halogen atom donors in an inner-sphere fashion. This controlled electron transfer limits undesired radical recombination products and promotes selective radical processes in electrochemical environments.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

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Article Chemistry, Multidisciplinary

On the mechanism of the formation of alkyl-Ni(i) catalysts

M. Teresa Quiros et al.

Summary: The formation of catalytically active alkyl-Ni(i) complexes through alkyl ligand exchange proceeds easily through triplet states, involving inversion of the configuration at the transferred carbon.

CHEMICAL COMMUNICATIONS (2021)

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Article Chemistry, Applied

Pyridine(diimine) Iron Diene Complexes Relevant to Catalytic [2+2]-Cycloaddition Reactions

C. Rose Kennedy et al.

ADVANCED SYNTHESIS & CATALYSIS (2020)

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Article Chemistry, Multidisciplinary

Investigations into the Mechanism of Inter- and Intramolecular Iron-Catalyzed [2+2] Cycloaddition of Alkenes

Matthew Joannou et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

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Article Chemistry, Multidisciplinary

Distal γ-C(sp3)-H Olefination of Ketone Derivatives and Free Carboxylic Acids

Han Seul Park et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

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Article Chemistry, Multidisciplinary

General Paradigm in Photoredox Nickel-Catalyzed Cross-Coupling Allows for Light-Free Access to Reactivity

Rui Sun et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

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Article Chemistry, Medicinal

Divergent Synthesis of Novel Cylindrocyclophanes that Inhibit Methicillin-ResistantStaphylococcus aureus(MRSA)

Julien J. Freudenreich et al.

CHEMMEDCHEM (2020)

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Article Chemistry, Multidisciplinary

Synthesis of Quaternary Carbon Stereogenic Centers by Diastereoselective Conjugate Addition of Boron-Stabilized Allylic Nucleophiles to Enones

Michael Z. Liang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

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Article Chemistry, Multidisciplinary

Mechanistic Studies Inform Design of Improved Ti(salen) Catalysts for Enantioselective [3+2] Cycloaddition

Sophia G. Robinson et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

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Article Chemistry, Multidisciplinary

Visible-light-induced triple catalysis for a ring-opening cyanation of cyclopropyl ketones

Jing Liu et al.

CHEMICAL COMMUNICATIONS (2020)

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Article Chemistry, Multidisciplinary

Rh(III)-Catalyzed C-H Activation-Initiated Directed Cyclopropanation of Allylic Alcohols

Erik J. T. Phipps et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

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Article Chemistry, Multidisciplinary

Exploration of a Chiral Cobalt Catalyst for Visible-Light-Induced Enantioselective Radical Conjugate Addition

Kai Zhang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

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Article Chemistry, Organic

Visible-Light-Induced Ring-Opening of Hydrogenolysis Spirocyclopropyl Oxindoles Through Photoredox Catalysis

Zhi-Ping Liu et al.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2019)

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Article Chemistry, Multidisciplinary

Si-H Bond Activation with Bullock's Cationic Tungsten(II) Catalyst: CO as Cooperating Ligand

Julien Fuchs et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

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Article Chemistry, Physical

SmI2-catalysed cyclization cascades by radical relay

Huan-Ming Huang et al.

NATURE CATALYSIS (2019)

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Article Chemistry, Multidisciplinary

Asymmetric [3+2] Photocycloadditions of Cyclopropanes with Alkenes or Alkynes through Visible-Light Excitation of Catalyst-Bound Substrates

Xiaoqiang Huang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

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Article Chemistry, Organic

Visible-Light-Activated Catalytic Enantioselective β-Alkylation of α, β-Unsaturated 2-Acyl Imidazoles Using Hantzsch Esters as Radical Reservoirs

Francisco F. de Assis et al.

JOURNAL OF ORGANIC CHEMISTRY (2018)

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Article Chemistry, Multidisciplinary

Diastereo- and Enantioselective Formal [3+2] Cycloaddition of Cyclopropyl Ketones and Alkenes via Ti-Catalyzed Radical Redox Relay

Wei Hao et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

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Article Chemistry, Multidisciplinary

Ligand-Enabled gamma-C(sp(3))-H Activation of Ketones

Ru-Yi Zhu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

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Article Chemistry, Organic

Direct Silyl-Heck Reaction of Chlorosilanes

Kazuhiro Matsumoto et al.

ORGANIC LETTERS (2018)

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Article Chemistry, Physical

One-Pot Photomediated Giese Reaction/Friedel-Crafts Hydroxyalkylation/Oxidative Aromatization To Access Naphthalene Derivatives from Toluenes and Enones

Haiwang Liu et al.

ACS CATALYSIS (2018)

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Article Chemistry, Organic

Access to Functionalized Quaternary Stereocenters via the Copper-Catalyzed Conjugate Addition of Monoorganozinc Bromide Reagents Enabled by N,N-Dimethylacetamide

Tyler J. Fulton et al.

JOURNAL OF ORGANIC CHEMISTRY (2018)

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Article Chemistry, Organic

Auto-Tandem Catalysis: Activation of Multiple, Mechanistically Distinct Process by a Single Catalyst

Jason E. Camp

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2017)

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Review Chemistry, Organic

Recent advances in asymmetric total synthesis of prostaglandins

Haihui Peng et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2017)

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Article Chemistry, Physical

Cut and Sew Transformations via Transition-Metal-Catalyzed Carbon-Carbon Bond Activation

Peng-hao Chen et al.

ACS CATALYSIS (2017)

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Review Chemistry, Multidisciplinary

Recent Methodologies That Exploit C-C Single-Bond Cleavage of Strained Ring Systems by Transition Metal Complexes

Gabriele Fumagalli et al.

CHEMICAL REVIEWS (2017)

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Article Chemistry, Multidisciplinary

Nickel-Catalyzed Esterification of Aliphatic Amides

Liana Hie et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

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Article Chemistry, Multidisciplinary

Rapid Construction of a Benzo-Fused Indoxamycin Core Enabled by Site-Selective C-H Functionalizations

T. Aaron Bedell et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

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Article Chemistry, Organic

Visible-Light Induced Direct Synthesis of Polysubstituted Furans from Cyclopropyl Ketones

Liyan Feng et al.

JOURNAL OF ORGANIC CHEMISTRY (2016)

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Article Chemistry, Multidisciplinary

Enantioselective Photocatalytic [3+2] Cycloadditions of Aryl Cyclopropyl Ketones

Adrian G. Amador et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

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Article Chemistry, Multidisciplinary

Catalytic, Enantioselective Addition of Alkyl Radicals to Alkenes via Visible-Light-Activated Photoredox Catalysis with a Chiral Rhodium Complex

Haohua Huo et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

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Article Chemistry, Physical

Recent Developments in Negishi Cross-Coupling Reactions

Diana Haas et al.

ACS CATALYSIS (2016)

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Review Chemistry, Multidisciplinary

Catalytic C-C Bond Activations via Oxidative Addition to Transition Metals

Laetitia Souillart et al.

CHEMICAL REVIEWS (2015)

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Article Chemistry, Multidisciplinary

Selective Intermolecular Oxidative Cross-Coupling of Enolates

Toru Amaya et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)

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Article Chemistry, Multidisciplinary

Chiral Bronsted Acid as a True Catalyst: Asymmetric Mukaiyama Aldol and Hosomi-Sakurai Allylation Reactions

Masahiro Sai et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)

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Article Chemistry, Multidisciplinary

Nickel-Catalyzed Cross-Coupling of Photoredox-Generated Radicals: Uncovering a General Manifold for Stereoconvergence in Nickel-Catalyzed Cross-Couplings

Osvaldo Gutierrez et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)

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Article Chemistry, Organic

Stereodivergent Synthesis of Enantioenriched 4-Hydroxy-2-cyclopentenones

Gurpreet Singh et al.

JOURNAL OF ORGANIC CHEMISTRY (2014)

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Article Chemistry, Multidisciplinary

A Highly Enantioselective Hydrogenation of Silyl Enol Ethers Catalyzed by Chiral Frustrated Lewis Pairs

Simin Wei et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)

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Article Chemistry, Multidisciplinary

Rh(III)-Catalyzed Cyclopropanation Initiated by C-H Activation: Ligand Development Enables a Diastereoselective [2+1] Annulation of N-Enoxyphthalimides and Alkenes

Tiffany Piou et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)

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Article Chemistry, Multidisciplinary

The Mukaiyama Aldol Reaction: 40Years of Continuous Development

Jun-ichi Matsuo et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)

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Review Chemistry, Multidisciplinary

Redox-active ligands in catalysis

Oana R. Luca et al.

CHEMICAL SOCIETY REVIEWS (2013)

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Article Chemistry, Organic

Palladium-Catalyzed Saegusa-Ito Oxidation: Synthesis of α,β-Unsaturated Carbonyl Compounds from Trimethylsilyl Enol Ethers

Yingdong Lu et al.

JOURNAL OF ORGANIC CHEMISTRY (2013)

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Article Multidisciplinary Sciences

Stereocontrolled organocatalytic synthesis of prostaglandin PGF2α in seven steps

Graeme Coulthard et al.

NATURE (2012)

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Article Chemistry, Organic

Total Synthesis of (-)-(α)-Kainic Acid via a Diastereoselective Intramolecular [3+2] Cycloaddition Reaction of an Aryl Cyclopropyl Ketone with an Alkyne

Zhi Luo et al.

ORGANIC LETTERS (2012)

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Article Chemistry, Organic

Intramolecular Condensation via an o-Quinone Methide: Total Synthesis of (±)-Heliol

Jason C. Green et al.

ORGANIC LETTERS (2012)

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Article Chemistry, Inorganic & Nuclear

Stoichiometric and Catalytic Reactions of Thermally Stable Nickel(0) NHC Complexes

Jianguo Wu et al.

ORGANOMETALLICS (2012)

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Article Chemistry, Inorganic & Nuclear

Synthesis, Electronic Structure, and Alkene Hydrosilylation Activity of Terpyridine and Bis(imino)pyridine Iron Dialkyl Complexes

Aaron M. Tondreau et al.

ORGANOMETALLICS (2012)

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Article Chemistry, Multidisciplinary

[3+2] Cycloaddition Reaction of Cyclopropyl Ketones with Alkynes Catalyzed by Nickel/Dimethylaluminum Chloride

Takashi Tamaki et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)

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Article Chemistry, Multidisciplinary

Practical Conversion of Chlorosilanes into Alkoxysilanes without Generating HCl

Ryutaro Wakabayashi et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)

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Review Chemistry, Multidisciplinary

Transition Metal Catalyzed Enantioselective α-Heterofunctionalization of Carbonyl Compounds

Alexander M. R. Smith et al.

CHEMICAL REVIEWS (2011)

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Article Chemistry, Multidisciplinary

Chiral Bronsted Acid from a Cationic Gold(I) Complex: Catalytic Enantioselective Protonation of Silyl Enol Ethers of Ketones

Cheol Hong Cheon et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

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Article Chemistry, Multidisciplinary

Pd(II)-Catalyzed Enantioselective C-H Activation of Cyclopropanes

Masayuki Wasa et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

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Article Chemistry, Multidisciplinary

[3+2] Cycloadditions of Aryl Cyclopropyl Ketones by Visible Light Photocatalysis

Zhan Lu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

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Article Chemistry, Organic

Nickel-Catalyzed Negishi Cross-Coupling Reactions of Secondary Alkylzinc Halides and Aryl Iodides

Amruta Joshi-Pangu et al.

ORGANIC LETTERS (2011)

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Article Chemistry, Inorganic & Nuclear

Synthesis, Properties, and Reactivity with Carbon Dioxide of (allyl)2Ni(L) Complexes

Jianguo Wu et al.

ORGANOMETALLICS (2011)

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Article Chemistry, Inorganic & Nuclear

Asymmetric synthesis of a dopamine D1 agonist, dihydrexidine from D-serine

Rajesh Malhotra et al.

TETRAHEDRON-ASYMMETRY (2011)

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Article Chemistry, Multidisciplinary

Nickel-catalyzed cross coupling of non-activated alkyl halides: a mechanistic perspective

Xile Hu

CHEMICAL SCIENCE (2011)

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Article Chemistry, Multidisciplinary

Nonhydrolytic Synthesis of Branched Alkoxysiloxane Oligomers Si[OSiH(OR)(2)](4) (R = Me, Et)

Rytnaro Wakabayashi et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)

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Article Chemistry, Multidisciplinary

Enantioselective Desymmetrization of Cyclopropenes by Hydroacylation

Diem H. T. Phan et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)

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Review Chemistry, Multidisciplinary

Nickel-catalysed Negishi cross-coupling reactions: scope and mechanisms

Vilas B. Phapale et al.

CHEMICAL SOCIETY REVIEWS (2009)

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Article Chemistry, Multidisciplinary

Synthesis and Reactivity of Six-Membered Oxa-Nickelacycles: A Ring-Opening Reaction of Cyclopropyl Ketones

Takashi Tamaki et al.

CHEMISTRY-A EUROPEAN JOURNAL (2009)

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Article Chemistry, Organic

Nickel-Catalyzed Borylation of Aryl Cyclopropyl Ketones with Bis(pinacolato)diboron to Synthesize 4-Oxoalkylboronates

Yuto Sumida et al.

JOURNAL OF ORGANIC CHEMISTRY (2009)

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Article Chemistry, Physical

Reversed redox generation of silyl radicals in a four-electrode flow-through EPR spectroelectrochemical cell

Joceline Zeitouny et al.

PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2009)

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Article Chemistry, Organic

Enantioselective Reactions of Donor/Acceptor Carbenoids Derived from α-Aryl-α-Diazoketones

Justin R. Denton et al.

ORGANIC LETTERS (2009)

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Article Chemistry, Multidisciplinary

Asymmetric Ni-catalyzed conjugate allylation of activated enones

Joshua D. Sieber et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)

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Article Chemistry, Organic

Palladium-Catalyzed Conjugate Allylation Reactions of α,β-Unsaturated N-Acylpyrroles

Michael B. Shaghafi et al.

ORGANIC LETTERS (2008)

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Article Biochemistry & Molecular Biology

Protein interactions in the human methionine synthase - Methionine synthase reductase complex and implications for the mechanism of enzyme reactivationt

Kirsten R. Wolthers et al.

BIOCHEMISTRY (2007)

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Article Chemistry, Organic

Synthesis of the tricyclic core of colchicine via a dienyne tandem ring-closing metathesis reaction

Francois-Didier Boyer et al.

ORGANIC LETTERS (2007)

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Article Chemistry, Multidisciplinary

Catalytic conjugate addition of allyl groups to styryl-activated enones

Joshua D. Sieber et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)

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Article Chemistry, Organic

Palladium-catalyzed regiocontrolled α-arylation of trimethylsilyl enol ethers with aryl halides

Tetsuo Iwama et al.

ORGANIC LETTERS (2006)

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Article Chemistry, Multidisciplinary

Ligand redox effects in the synthesis, electronic structure, and reactivity of an alkyl-alkyl cross-coupling catalyst

Gavin D. Jones et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)

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Article Chemistry, Multidisciplinary

Dimerization of cyclopropyl ketones and crossed reactions of cyclopropyl ketones with enones as an entry to five-membered rings

L Liu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)

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