Mechano-energetic efficiency in patients with hypertrophic cardiomyopathy with and without sarcomeric mutations

Article Cardiac & Cardiovascular Systems

Prognostic Stratification of Clinically Stable Patients with Heart Failure by Echocardiographic Pressure/Volume Loop Model

Giovanni Cioffi et al.

Summary: The authors developed a noninvasive method to compute individualized P/V loops to predict adverse clinical outcomes in patients with stable HF, which the authors believe can be used clinically.

JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY (2023)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Diagnosis and Evaluation of Hypertrophic Cardiomyopathy JACC State-of-the-Art Review

Barry J. Maron et al.

Summary: Hypertrophic cardiomyopathy (HCM) is a common global heart disease with complex phenotypic and genetic expression. Improvements in management strategies have led to better clinical outcomes. Reliable diagnosis with echocardiography and cardiac magnetic resonance, along with family screening and genetic analysis, play important roles in identifying patients and carriers.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2022)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Automated three-dimensional echocardiographic quantification for left ventricular volume and function in patients with hypertrophic cardiomyopathy

Yushan Wang et al.

Summary: Compared with current clinical 2DBP method, the analysis time of automated 3DE was much shorter with the added benefit of enhanced accuracy and reproducibility. Patients with asymmetric chamber may rely more on the timesaving automated 3DE quantification in the future.

ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES (2022)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Changing concepts in heart muscle disease: the evolving understanding of hypertrophic cardiomyopathy

William E. Moody et al.

Summary: The recognition and improved diagnostic techniques for hypertrophic cardiomyopathy (HCM) have led to earlier and more effective management, resulting in improved life expectancy and quality of life for patients. Advances in molecular genetics and novel therapies offer exciting prospects for the future treatment of HCM.

HEART (2022)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Minor hypertrophic cardiomyopathy genes, major insights into the genetics of cardiomyopathies

Roddy Walsh et al.

Summary: This review explores the complex contribution of genes encoding non-sarcomeric proteins associated with non-syndromic or isolated hypertrophic cardiomyopathy to the genetics of cardiomyopathies. The study highlights the role of various genes in the pathogenesis of cardiomyopathies and the overlapping genetic basis between hypertrophic cardiomyopathy and dilated cardiomyopathy. This overlap extends to rare Mendelian variants with distinct variant classes in several genes associated with both types of cardiomyopathy.

NATURE REVIEWS CARDIOLOGY (2022)

添加到收藏夹

Article Health Care Sciences & Services

Physiologic Range of Myocardial Mechano-Energetic Efficiency among Healthy Subjects: Impact of Gender and Age

Francesco Ferrara et al.

Summary: This study established normal non-invasive myocardial mechano-energetic efficiency (MEE) and indexed MEE reference values, which can improve the global assessment of left ventricular cardiac mechanics and serve as a reference to identify phenotypes at high risk of cardiovascular events.

JOURNAL OF PERSONALIZED MEDICINE (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Next-Generation Sequencing Gene Panels in Inheritable Cardiomyopathies and Channelopathies: Prevalence of Pathogenic Variants and Variants of Unknown Significance in Uncommon Genes

Cristina Mazzaccara et al.

Summary: The detection of pathogenic mutations in cardiomyopathies and channelopathies has been enhanced through the use of next-generation sequencing (NGS) and the inclusion of uncommon genes in molecular testing.

BIOMOLECULES (2022)

添加到收藏夹

Article Genetics & Heredity

Common genetic variants and modifiable risk factors underpin hypertrophic cardiomyopathy susceptibility and expressivity

Andrew R. Harper et al.

Summary: The study identified 12 genome-wide significant susceptibility loci for HCM, showing a strong polygenic influence, especially for sarcomere-negative HCM. A genetic risk score influenced the odds of HCM and phenotypic severity in carriers of sarcomere variants. Mendelian randomization identified diastolic blood pressure as a key modifiable risk factor for sarcomere-negative HCM.

NATURE GENETICS (2021)

添加到收藏夹

Editorial Material Cardiac & Cardiovascular Systems

Time to Think Differently About Sarcomere-Negative Hypertrophic Cardiomyopathy

Hugh Watkins

CIRCULATION (2021)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Prevalence of cardiac amyloidosis among adult patients referred to tertiary centres with an initial diagnosis of hypertrophic cardiomyopathy

Niccolo Maurizi et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2020)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Invasive left ventricle pressure-volume analysis: overview and practical clinical implications

Marcelo B. Bastos et al.

EUROPEAN HEART JOURNAL (2020)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Left Ventricular Mass in Hypertrophic Cardiomyopathy Assessed by 2D-Echocardiography: Validation with Magnetic Resonance Imaging

Maria Angela Losi et al.

JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH (2020)

添加到收藏夹

Review Medicine, General & Internal

Depressed Cardiac Mechanical Energetic Efficiency: A Contributor to Cardiovascular Risk in Common Metabolic Diseases-From Mechanisms to Clinical Applications

Albert Juszczyk et al.

JOURNAL OF CLINICAL MEDICINE (2020)

添加到收藏夹

Article Medicine, General & Internal

Depressed Myocardial Energetic Efficiency Increases Risk of Incident Heart Failure: The Strong Heart Study

Maria-Angela Losi et al.

JOURNAL OF CLINICAL MEDICINE (2019)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Distinct Subgroups in Hypertrophic Cardiomyopathy in the NHLBI HCM Registry

Stefan Neubauer et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2019)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Evaluating the Clinical Validity of Hypertrophic Cardiomyopathy Genes

Jodie Ingles et al.

CIRCULATION-GENOMIC AND PRECISION MEDICINE (2019)

添加到收藏夹

Article Genetics & Heredity

Genetic evaluation of cardiomyopathy: a clinical practice resource of the American College of Medical Genetics and Genomics (ACMG)

Ray E. Hershberger et al.

GENETICS IN MEDICINE (2018)

添加到收藏夹

Article Peripheral Vascular Disease

Effect of diabetes and metabolic syndrome on myocardial mechano-energetic efficiency in hypertensive patients. The Campania Salute Network

C. Mancusi et al.

JOURNAL OF HUMAN HYPERTENSION (2017)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Hypertrophic Cardiomyopathy Genetics, Pathogenesis, Clinical Manifestations, Diagnosis, and Therapy

Ali J. Marian et al.

CIRCULATION RESEARCH (2017)

添加到收藏夹

Article Peripheral Vascular Disease

Depressed myocardial energetic efficiency is associated with increased cardiovascular risk in hypertensive left ventricular hypertrophy

Giovanni de Simone et al.

JOURNAL OF HYPERTENSION (2016)

添加到收藏夹

Article Genetics & Heredity

Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology

Sue Richards et al.

GENETICS IN MEDICINE (2015)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Gene-specific increase in the energetic cost of contraction in hypertrophic cardiomyopathy caused by thick filament mutations

E. RosalieWitjas-Paalberends et al.

CARDIOVASCULAR RESEARCH (2014)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

2014 ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy The Task Force for the Diagnosis and Management of Hypertrophic Cardiomyopathy of the European Society of Cardiology (ESC)

Perry M. Elliott et al.

EUROPEAN HEART JOURNAL (2014)

添加到收藏夹

Editorial Material Medicine, General & Internal

被撤回的出版物: World Medical Association Declaration of Helsinki Ethical Principles for Medical Research Involving Human Subjects (Retracted article. See vol. 135, pg. 2149, 2021)

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2013)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Clinical Utility of Cardiovascular Magnetic Resonance in Hypertrophic Cardiomyopathy

Martin S. Maron

JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE (2012)

添加到收藏夹

Article Peripheral Vascular Disease

Myocardial mechano-energetic efficiency in hypertensive adults

Giovanni de Simone et al.

JOURNAL OF HYPERTENSION (2009)

添加到收藏夹

Article Genetics & Heredity

Decreased contractility due to energy deprivation in a transgenic rat model of hypertrophic cardiomyopathy

Mark Luedde et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2009)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Contemporary definitions and classification of the cardiomyopathies - An American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; And Council on Epidemiology and Prevention

BJ Maron et al.

CIRCULATION (2006)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Assessment of systolic and diastolic ventricular properties via pressure-volume analysis: a guide for clinical, translational, and basic researchers

D Burkhoff et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2005)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Evolution of expression of cardiac phenotypes over a 4-year period in the β-myosin heavy chain-Q403 transgenic rabbit model of human hypertrophic cardiomyopathy

SF Nagueh et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2004)

添加到收藏夹

Mechano-energetic efficiency in patients with hypertrophic cardiomyopathy with and without sarcomeric mutations

相关参考文献

导出引文

分享论文