4.6 Article

In vitro and in vivo evaluation of the antimicrobial effectiveness of non-medicated hydrophobic wound dressings

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Dermatology

The biological and physiological impact of the performance of wound dressings

Breda Cullen et al.

Summary: Chronic wounds are a global issue that not only affects patients' health but also imposes a significant burden on society. This review explores the reasons for wound healing failure, the pathophysiology of chronic wounds, and the design and evaluation of dressings. It emphasizes the importance of understanding wound exudates and developing laboratory models for testing dressings. The findings have significant implications for improving dressing effectiveness, enhancing patient outcomes, and reducing the economic burden of chronic wounds.

INTERNATIONAL WOUND JOURNAL (2023)

Review Biochemistry & Molecular Biology

Nutrient Sensing and Biofilm Modulation: The Example of L-arginine in Pseudomonas

Chiara Scribani Rossi et al.

Summary: Bacterial biofilm is a multicellular community that provides protection to bacterial cells against harsh environments. Pseudomonas genus is known for its strong biofilm formation and metabolic versatility. Nutrient availability can be sensed by a Pseudomonas biofilm, which adjusts its metabolism accordingly. L-arginine, an amino acid, plays a crucial role in bacterial growth and is associated with biofilm formation, virulence, and antibiotic resistance.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Article Biology

Inhibiting host-protein deposition on urinary catheters reduces associated urinary tract infections

Marissa Jeme Andersen et al.

Summary: Microbial adhesion to medical devices, particularly urinary catheters, is a common issue in hospital-acquired infections. This study found that the deposition of host proteins, particularly fibrinogen, on urinary catheters provides an advantage for uropathogens in persisting despite antibiotic treatments. Targeting catheter protein deposition may be an effective intervention for reducing colonization and treating catheter-associated urinary tract infections (CAUTIs).
Article Microbiology

A Relevant Wound-Like in vitro Media to Study Bacterial Cooperation and Biofilm in Chronic Wounds

Cassandra Pouget et al.

Summary: Biofilm on the skin surface of chronic wounds inhibits wound healing. This study developed a new in vitro medium that mimics the microbiological, cellular, and inflammatory environment of chronic wounds, focusing on pH level. The study found that the chronic wound environment affects biofilm formation and bacteria virulence, and that Pseudomonas aeruginosa and Staphylococcus aureus cooperate in coinfected wounds.

FRONTIERS IN MICROBIOLOGY (2022)

Article Dermatology

Establishing a consensus on wound infection definitions

Emily Haesler et al.

Summary: The objective of this study was to establish an international, interorganisational consensus on wound infection terminology. The study utilized the Delphi process and an online consensus method to generate a glossary of wound infection terms, endorsed by 15 international organizations. The resulting glossary serves as a valuable resource for guidelines and clinical decision-making/teaching tools.

JOURNAL OF WOUND CARE (2022)

Article Microbiology

Inoculum Concentration Influences Pseudomonas aeruginosa Phenotype and Biofilm Architecture

Mads Lichtenberg et al.

Summary: The study investigated how initial bacterial concentration influences the microenvironment and aggregate development in a biofilm model. Results showed differences in metabolic activity and antibiotic tolerance based on the inoculum, indicating the importance of microenvironmental characteristics in shaping bacterial phenotypes.

MICROBIOLOGY SPECTRUM (2022)

Article Dermatology

Antimicrobial effects of bacterial binding to a dialkylcarbamoyl chloride-coated wound dressing: an in vitro study

Johanna Husmark et al.

Summary: Wound dressings with a hydrophobic, bacteria-binding DACC surface can effectively reduce the risk of clinical infections, especially in hard-to-heal wounds. The study found that the DACC-coated dressing has strong antibacterial effects under different conditions and can sustain infection resistance.

JOURNAL OF WOUND CARE (2022)

Article Dermatology

Significant and rapid reduction of free endotoxin using a dialkylcarbamoyl chloride-coated wound dressing

Yusak Budi Susilo et al.

Summary: In this study, it was demonstrated that a DACC-coated wound dressing efficiently binds both purified and shed endotoxin from Pseudomonas aeruginosa, which could potentially promote wound healing.

JOURNAL OF WOUND CARE (2022)

Article Dermatology

Efficacy of a topical concentrated surfactant gel on microbial communities in non-healing diabetic foot ulcers with chronic biofilm infections: A proof-of-concept study

Matthew Malone et al.

Summary: The study demonstrated that the application of a concentrated surfactant gel had a significant impact on both the microbial load and community composition of non-healing diabetic foot ulcers, resulting in a reduction in microbial load and changes in microbial community composition.

INTERNATIONAL WOUND JOURNAL (2021)

Article Microbiology

Milieu matters: An in vitro wound milieu to recapitulate key features of, and probe new insights into, mixed-species bacterial biofilms

Snehal Kadam et al.

Summary: The study demonstrates the potential of using an in vitro wound milieu (IVWM) to mimic in vivo biofilm features, including biomass formation, metabolic activity, antibiotic tolerance, and interspecies interactions. The IVWM is simple to formulate, uses laboratory-grade components, and is compatible with standard biofilm assays, making it a promising approach for studying wound biofilms under host-relevant conditions.

BIOFILM (2021)

Article Chemistry, Multidisciplinary

Different binding mechanisms ofStaphylococcus aureusto hydrophobic and hydrophilic surfaces

Erik Maikranz et al.

NANOSCALE (2020)

Article Nanoscience & Nanotechnology

Biomaterial Surface Hydrophobicity-Mediated Serum Protein Adsorption and Immune Responses

Rahul M. Visalakshan et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

Article Multidisciplinary Sciences

Entropically driven aggregation of bacteria by host polymers promotes antibiotic tolerance in Pseudomonas aeruginosa

Patrick R. Secor et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Review Immunology

Pseudomonas aeruginosa in Chronic Lung Infections: How to Adapt Within the Host?

Emmanuel Faure et al.

FRONTIERS IN IMMUNOLOGY (2018)

Article Biotechnology & Applied Microbiology

The Inoculation Method Could Impact the Outcome of Microbiological Experiments

Kasper Norskov Kragh et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2018)

Article Dermatology

Temporal Stability in Chronic Wound Microbiota Is Associated With Poor Healing

Michael Loesche et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2017)

Article Dermatology

Adhesion of meticillin-resistant Staphylococcus aureus to DACC-coated dressings

A. C. Ronner et al.

JOURNAL OF WOUND CARE (2014)

Letter Microbiology

The Dual Personality of Iron Chelators: Growth Inhibitors or Promoters?

Paolo Visca et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2013)

Article Microbiology

Antibacterial Activities of Iron Chelators against Common Nosocomial Pathogens

Mitchell G. Thompson et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2012)

Article Infectious Diseases

Panbacterial real-time PCR to evaluate bacterial burden in chronic wounds treated with Cutimed™ Sorbact™

V. Gentili et al.

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (2012)

Review Multidisciplinary Sciences

Biofouling: lessons from nature

Gregory D. Bixler et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES (2012)

Article Chemistry, Physical

The role of conditioning film formation and surface chemical changes on Xylella fastidiosa adhesion and biofilm evolution

Gabriela S. Lorite et al.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2011)

Article Surgery

Serum Inhibits P. aeruginosa Biofilm Formation on Plastic Surfaces and Intravenous Catheters

Adrienne Hammond et al.

JOURNAL OF SURGICAL RESEARCH (2010)

Article Immunology

Topical Antimicrobial Therapy for Treating Chronic Wounds

Benjamin A. Lipsky et al.

CLINICAL INFECTIOUS DISEASES (2009)

Article Engineering, Biomedical

The inhibitory activity of serum to prevent bacterial adhesion is mainly due to apo-transferrin

R Ardehali et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2003)