4.7 Article

BoLA-DRB3*15:01 allele is associated with susceptibility to early enzootic bovine leukosis onset in Holstein-Friesian and Japanese Black cattle

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Multidisciplinary Sciences

Phylogenetic analysis based on whole genome sequence of bovine leukemia virus in cattle under 3 years old with enzootic bovine leukosis

Masaki Maezawa et al.

Summary: Enzootic bovine leukosis (EBL) is a type of bovine neoplasm caused by bovine leukemia virus (BLV). EBL is typically seen in cattle over 3 years old, but cases of EBL in young cattle have been reported in Japan. This study aimed to investigate the relationship between early onset EBL and BLV groups, as well as characterize the BLV strains responsible for early onset EBL. Genetic analysis revealed that BLV in young EBL cattle belonged to groups A and B-1, while BLV in older EBL cattle belonged to group B-2. Specific genetic variations in various regions of the viral genome were identified, which could contribute to the early onset of EBL.

PLOS ONE (2023)

Article Veterinary Sciences

Enzootic bovine leukosis in a 21-month-old Japanese Black cow with high susceptibility

Masaki Maezawa et al.

Summary: This study investigated a case of enzootic bovine leukosis in a Japanese Black beef cow, identifying various pathological and genetic features associated with the disease.

JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION (2022)

Article Veterinary Sciences

Epidemiological evidence for early-onset of enzootic bovine leukosis by L233-Tax- carrying bovine leukemia virus in Japanese Black cattle

Takafumi Tomiyasu et al.

Summary: A nationwide surveillance of Japanese Black cattle revealed that the occurrence of bovine leukemia virus (BLV) is associated with the amino acid at position 233 in the Tax protein. The study also found that BLV carrying L233-Tax is more common in animals born via embryo transfer and in dairy areas. These findings contribute to the prevention of enzootic bovine leukosis (EBL).

JOURNAL OF VETERINARY MEDICAL SCIENCE (2022)

Article Microbiology

Association of Bovine Leukemia Virus-Induced Lymphoma with BoLA-DRB3 Polymorphisms at DNA, Amino Acid, and Binding Pocket Property Levels

Chieh-Wen Lo et al.

Summary: This study revealed that different alleles of BoLA-DRB3 are associated with susceptibility to BLV-induced lymphoma in cattle, with certain amino acid positions showing correlation with lymphoma susceptibility. Additionally, the study showed that the binding pocket of resistance DRB3 is positively charged, while susceptible DRB3 alleles are neutrally charged.

PATHOGENS (2021)

Article Veterinary Sciences

Analysis of the bone morphogenetic protein 6 gene promoter region in young beef cattle affected by enzootic bovine leukosis

Masaki Maezawa et al.

Summary: This study finds that the methylation rate of the BMP-6 promoter region in EBL beef cattle under 3 years old is significantly higher than in other groups. Hypermethylation of the BMP-6 promoter region may contribute to the early onset of EBL in beef cattle under 3 years old, and specific animal feeding management practices for beef cattle may affect the methylation status of the BMP-6 promoter region.

JOURNAL OF VETERINARY MEDICAL SCIENCE (2021)

Article Veterinary Sciences

Molecular diagnosis of bovine B-cell lymphoma using polymerase chain reaction for immunoglobulin heavy chain gene

Masaki Maezawa et al.

JOURNAL OF VETERINARY MEDICAL SCIENCE (2020)

Article Virology

Enzootic bovine leukosis in a two-month-old calf

Keisuke Oguma et al.

VIRUS RESEARCH (2017)

Article Biotechnology & Applied Microbiology

The Functional Significance of Cattle Major Histocompatibility Complex Class I Genetic Diversity

Shirley A. Ellis et al.

ANNUAL REVIEW OF ANIMAL BIOSCIENCES, VOL 2 (2014)

Review Agriculture, Dairy & Animal Science

Structure, function and disease susceptibility of the bovine major histocompatibility complex

SN Takeshima et al.

ANIMAL SCIENCE JOURNAL (2006)

Article Cell Biology

Establishment of a sequence-based typing system for BoLA-DRB3 exon 2

D Miltiadou et al.

TISSUE ANTIGENS (2003)