Cold blooded vertebrates help unveil a heat-dependent trigger

In a recent study, Flori and colleagues demonstrated that two specific residues located in the first ankyrin repeat of TRPV1 chan-nels modulate the threshold for temperature activation. This study highlights the importance of con-sidering natural diversity and com-parative biology when approaching biophysical questions.

Automated summary

A recent study reveals that two specific residues in the first ankyrin repeat of TRPV1 channels modulate the threshold for temperature activation, emphasizing the importance of considering natural diversity and comparative biology.