Macrolide esterases: current threats and opportunities

Antibiotics often contain ester bonds. The macrocyclic lactones of macrolides are pre-eminent examples in which ester bonds are essential to the form and function of antibiotics. Bacterial macrolide esterases that hydrolyze these macrocyclic lactones to confer antimicrobial resistance (AMR) are the topic of this forum. We provide insight into their role in agricultural systems and discuss their emergence and their potential extensibility to bioremediation efforts.

Automated summary

This forum discusses the important role of bacterial macrolide esterases in antibiotics, as well as their potential applications in agricultural systems and bioremediation efforts.