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CRISPR/Cas9 boosts wheat yield by reducing brassinosteroid signaling

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TRENDS IN BIOCHEMICAL SCIENCES
卷 48, 期 11, 页码 917-919

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CELL PRESS
DOI: 10.1016/j.tibs.2023.07.005

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This study reports a new strategy to create high-yielding, semi-dwarf wheat varieties with improved nitrogen-use efficiency by inhibiting brassinosteroid signaling through CRISPR/Cas9-mediated knockout of the ZnF-B gene encoding a zinc-finger RING-type E3 ligase.
A modern green revolution is needed to ensure global food security. Re-cently, Song et al. reported a new strategy to create high-yielding, semi-dwarf wheat varieties with im-proved nitrogen-use efficiency by inhibiting brassinosteroid (BR) sig-naling through clustered regularly interspaced short palindromic re-peats (CRISPR)/CRISPR-associated protein9 (Cas9)-mediated knockout of the ZnF-B gene encoding a zinc-finger RING-type E3 ligase.

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