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Elizabeth A. Doggett et al.
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D. W. Dickson et al.
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Wataru Satake et al.
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Javier Simon-Sanchez et al.
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Daniel G. Healy et al.
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J. Alegre-Abarrategui et al.
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Mahaboobi Jaleel et al.
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Saskia Biskup et al.
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AB West et al.
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