☆ 4.4 Article

Iron-catalyzed dimerization of pyrrolo[2,1-a]isoquinolines and pyrrolo [1,2-a]quinolines

TETRAHEDRON LETTERS (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Chemistry, Organic

Nitration of Pyrrolo[2,1-a]isoquinolines

Xiao-Hui Chen et al.

Summary: We have successfully modified a series of pyrrolo[2,1-a]isoquinolines via direct nitration under mild reaction conditions. Easily accessible nitrates including CAN, Cu(NO3)2 center dot H2O, and Fe(NO3)3 center dot 9H2O all can serve as effective nitrating reagents for functionalizing pyrrolo[2,1-a]isoquinolines. Various nitro-bearing pyrrolo[2,1-a]isoquinolines have been efficiently prepared in acceptable to good yields.

JOURNAL OF ORGANIC CHEMISTRY (2023)

添加到收藏夹

Article Chemistry, Organic

Bromination of Pyrrolo[2,1-a]isoquinolines with Acetyl Bromide and Dimethyl Sulfoxide

Hai-Lei Cui

Summary: A mild bromination of pyrrolo[2,1-a]isoquinolines using acetyl bromide and dimethyl sulfoxide has been achieved. The method provides brominated pyrrolo[2,1-a]isoquinolines in moderate to excellent yields (46-99%) at room temperature. The strategy can also be applied to the easy bromination of polysubstituted pyrroles, indoles, electron-rich phenols, aniline, and 2-naphthol.

JOURNAL OF ORGANIC CHEMISTRY (2023)

添加到收藏夹

Article Chemistry, Organic

Modification of Pyrrolo[2,1-a]isoquinolines and Pyrrolo[1,2-a]quinolines with Ammonium Acetate and Dimethyl Sulfoxide via Methylthiomethylation

Jia-Qin Li et al.

Summary: An efficient methylthiomethylation of pyrroloisoquinolines and pyrroloquinolines has been achieved using ammonium acetate and dimethyl sulfoxide. Moderate to good yields of methylthiomethylated heterocycles can be obtained in most cases, with trace amounts to good yields of methylene-bridged products observed. The chemoselectivity of this process is greatly influenced by the choice of DMSO activator and its amount. It is also noteworthy that the process is scalable and the product can easily be transformed to sulfone and sulfoxide.

JOURNAL OF ORGANIC CHEMISTRY (2022)

添加到收藏夹

Review Chemistry, Multidisciplinary

HFIP in Organic Synthesis

Hashim F. Motiwala et al.

Summary: HFIP is a polar solvent that is widely used in organic synthesis for stabilizing ionic species, transferring protons, and engaging in various intermolecular interactions.

CHEMICAL REVIEWS (2022)

添加到收藏夹

Article Chemistry, Organic

Modification of Pyrrolo[2,1-a]isoquinolines and Polysubstituted Pyrroles via Methylenation with Acetyl Chloride and Dimethylsulfoxide

Wan-Zhen Li et al.

Summary: A convenient synthesis method for methylene-bridged pyrrolo[2,1-a]isoquinolines has been developed, yielding bispyrroloisoquinolylmethanes and bispyrrolylmethanes in good yields. This synthesis method also allows for easy chemical transformation of the methylene-bridged pyrroloisoquinoline, providing unsymmetric acids and amides with a privileged framework.

JOURNAL OF ORGANIC CHEMISTRY (2022)

添加到收藏夹

Review Chemistry, Organic

Recent progress in the synthesis of pyrrolo[2,1-a]isoquinolines

Hai-Lei Cui

Summary: Pyrrolo[2,1-a]isoquinolines are commonly found in a wide range of bioactive natural products and pharmaceutically important molecules. The synthesis of pyrrolo[2,1-a]isoquinoline derivatives provides an easy and useful approach to create artificial molecules with potential applications. Numerous excellent methodologies for constructing pyrrolo[2,1-a]isoquinolines have been reported in the past decade.

ORGANIC & BIOMOLECULAR CHEMISTRY (2022)

添加到收藏夹

Article Chemistry, Organic

Formylation and Bromination of Pyrrolo[2,1-a]isoquinoline Derivatives with Bromoisobutyrate and Dimethyl Sulfoxide

Jia-Qin Li et al.

Summary: An efficient formylation method for pyrroloisoquinolines using bromoisobutyrate and dimethyl sulfoxide as carbonyl reagent has been developed, providing good yields of formylated products (up to 94%) which can be scaled up easily. Additionally, the combination of bromoisobutyrate and dimethyl sulfoxide can also act as a bromination reagent for pyrroloisoquinolines without methoxy groups, yielding brominated products in acceptable to good yields (up to 82%).

JOURNAL OF ORGANIC CHEMISTRY (2021)

添加到收藏夹

Article Chemistry, Organic

FeCl2 catalyzed direct modification of dihydropyrrolo[2,1-a]isoquinolines with phenols

Hai-Lei Cui

ORGANIC & BIOMOLECULAR CHEMISTRY (2020)

添加到收藏夹

Article Chemistry, Organic

Recent progress in (hetero)arene cation radical-based heteroarene modification

Hai-Lei Cui

ORGANIC & BIOMOLECULAR CHEMISTRY (2020)

添加到收藏夹

Article Chemistry, Organic

FeCl3 mediated dimerization of dihydropyrrolo[2,1-a]isoquinolines and chlorination of tetrasubstituted pyrroles

Xue-Fei Jiang et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Convenient Synthesis of 6,7,12,13-Tetrahydro-5H-Cyclohepta[2,1-b:3,4-b′]diindole Derivatives Mediated by Hypervalent Iodine (III) Reagent

Lei Peng et al.

MOLECULES (2019)

添加到收藏夹

Article Chemistry, Applied

Direct Synthesis of Dihydropyrrolo[2,1-a]Isoquinolines through FeCl3 Promoted Oxidative Aromatization

Hai-Lei Cui et al.

ADVANCED SYNTHESIS & CATALYSIS (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Cobalt-catalyzed cross-dehydrogenative coupling between N-(2-pyridyl) and free indoles for the synthesis of unsymmetrical 2,2′-biindoles

Ting Li et al.

CHEMICAL COMMUNICATIONS (2019)

添加到收藏夹

Article Plant Sciences

Pyrrolo[2,1-a]isoquinoline and pyrrole alkaloids from Sinomenium acutum

Hai-Ning Lv et al.

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2018)

添加到收藏夹

Article Chemistry, Organic

Aerobic, Metal-Free, and Catalytic Dehydrogenative Coupling of Heterocycles: En Route to Hedgehog Signaling Pathway Inhibitors

Luis Bering et al.

ORGANIC LETTERS (2018)

添加到收藏夹

Review Chemistry, Organic

Metal-free Oxidative Cross-Coupling Reaction of Aromatic Compounds Containing Heteroatoms

Koji Morimoto et al.

SYNLETT (2017)

添加到收藏夹

Article Chemistry, Medicinal

5,6-Dihydropyrrolo[2,1-a]isoquinolines as Alternative of New Drugs with Cytotoxic Activity

Rosa Maria Chavez-Santos et al.

CHEMICAL & PHARMACEUTICAL BULLETIN (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Palladium-Catalyzed Synthesis of Heteroarene-Fused Cyclooctatetraenes through Dehydrogenative Cyclodimerization

Keita Fukuzumi et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

添加到收藏夹

Review Chemistry, Multidisciplinary

Oxidative C-H/C-H Coupling Reactions between Two (Hetero)arenes

Yudong Yang et al.

CHEMICAL REVIEWS (2017)

添加到收藏夹

Article Chemistry, Applied

Carbocatalysed Oxidative Csp2-Csp2 Homocouplings of Benzo-Fused Heterocycles

Tom Wirtanen et al.

ADVANCED SYNTHESIS & CATALYSIS (2015)

添加到收藏夹

Article Chemistry, Applied

Regioselective Oxidative Homocoupling Reaction: An Efficient Copper-Catalyzed Synthesis of Biimidazo[1,2-a]pyridines

Sai Lei et al.

ADVANCED SYNTHESIS & CATALYSIS (2015)

添加到收藏夹

Article Chemistry, Multidisciplinary

Significant Enhancement in the Efficiency and Selectivity of Iron-Catalyzed Oxidative Cross-Coupling of Phenols by Fluoroalcohols

Eden Gaster et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

添加到收藏夹

Review Chemistry, Multidisciplinary

Iron Catalysis in Organic Synthesis

Ingmar Bauer et al.

CHEMICAL REVIEWS (2015)

添加到收藏夹

Review Biochemistry & Molecular Biology

Iron-promoted C-C bond formation in the total synthesis of natural products and drugs

Julien Legros et al.

NATURAL PRODUCT REPORTS (2015)

添加到收藏夹

Article Chemistry, Organic

Cobalt-Promoted Dimerization of Aminoquinoline Benzamides

Liene Grigorjeva et al.

ORGANIC LETTERS (2015)

添加到收藏夹

Review Chemistry, Applied

Synthesis of Biaryls through Aromatic CH Bond Activation: A Review of Recent Developments

Ibrar Hussain et al.

ADVANCED SYNTHESIS & CATALYSIS (2014)

添加到收藏夹

Article Chemistry, Multidisciplinary

The synthesis of 5-alkyl[3,4-c] thienopyrrole-4,6-dione-based polymers using a Pd-catalyzed oxidative C-H/C-H homopolymerization reaction

Qiang Zhang et al.

CHEMICAL COMMUNICATIONS (2014)

添加到收藏夹

Article Chemistry, Organic

COPPER-MEDIATED REGIOSELECTIVE HOMOCOUPLING OF THIOPHENES AND INDOLES VIA DIRECTED C-H CLEAVAGE

Riko Odani et al.

HETEROCYCLES (2014)

添加到收藏夹

Article Chemistry, Organic

Total Synthesis, Stereochemical Assignment, and Biological Activity of All Known (-)-Trigonoliimines

Sunkyu Han et al.

JOURNAL OF ORGANIC CHEMISTRY (2014)

添加到收藏夹

Article Chemistry, Organic

Palladium-Catalyzed C-H Homocoupling of Furans and Thiophenes Using Oxygen as the Oxidant

Na-Na Li et al.

ORGANIC LETTERS (2014)

添加到收藏夹

Review Chemistry, Multidisciplinary

Comparison of Oxidative Aromatic Coupling and the Scholl Reaction

Marek Grzybowski et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)

添加到收藏夹

Review Chemistry, Multidisciplinary

Chiral Iron Catalysts for Asymmetric Synthesis

Kovuru Gopalaiah

CHEMICAL REVIEWS (2013)

添加到收藏夹

Review Chemistry, Multidisciplinary

Semiconducting π-Conjugated Systems in Field-Effect Transistors: A Material Odyssey of Organic Electronics

Chengliang Wang et al.

CHEMICAL REVIEWS (2012)

添加到收藏夹

Article Chemistry, Organic

Copper(II)-Catalyzed Dehydrogenative Cross-Coupling between Two Azoles

Xurong Qin et al.

JOURNAL OF ORGANIC CHEMISTRY (2012)

添加到收藏夹

Article Chemistry, Medicinal

Structure Elucidation and Anticancer Activity of 7-Oxostaurosporine Derivatives from the Brazilian Endemic Tunicate Eudistoma vannamei

Paula Christine Jimenez et al.

MARINE DRUGS (2012)

添加到收藏夹

Article Chemistry, Organic

A palladium-catalyzed one-pot procedure for the regioselective dimerization and cyanation of indoles

Ebrahim Kianmehr et al.

TETRAHEDRON LETTERS (2012)

添加到收藏夹

Review Chemistry, Multidisciplinary

Direct C-H Transformation via Iron Catalysis

Chang-Liang Sun et al.

CHEMICAL REVIEWS (2011)

添加到收藏夹

Article Chemistry, Organic

Metal-Free Oxidative Coupling Reactions via σ-Iodonium Intermediates: The Efficient Synthesis of Bithiophenes Using Hypervalent Iodine Reagents

Koji Morimoto et al.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2011)

添加到收藏夹

Review Chemistry, Organic

SYNTHESIS AND BIOLOGICAL ACTIVITY OF LAMELLARIN ALKALOIDS: AN OVERVIEW

Tsutomu Fukuda et al.

HETEROCYCLES (2011)

添加到收藏夹

Article Chemistry, Multidisciplinary

Total Synthesis of (±)-Trigonoliimine C via Oxidative Rearrangement of an Unsymmetrical Bis-Tryptamine

Xiangbing Qi et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

添加到收藏夹

Article Chemistry, Organic

Synthesis of Indole and Biindolyl Triflones: Trifluoromethanesulfonylation of Indoles with Tf2O/TTBP (2,4,6-tri-tert-butylpyridine) System

Xiu-Hua Xu et al.

ORGANIC LETTERS (2011)

添加到收藏夹

Article Chemistry, Organic

A biomimetic synthesis of the skeleton of trigonoliimine C

Sheng Liu et al.

TETRAHEDRON LETTERS (2011)

添加到收藏夹

Article Chemistry, Multidisciplinary

Oxidative dimerization of N-protected and free indole derivatives toward 3,3 '-biindoles via Pd-catalyzed direct C-H transformations

Yang Li et al.

CHEMICAL COMMUNICATIONS (2010)

添加到收藏夹

Article Chemistry, Multidisciplinary

Pd-II-Catalysed C-H Functionalisation of Indoles and Pyrroles Assisted by the Removable N-(2-Pyridyl)sulfonyl Group: C2-Alkenylation and Dehydrogenative Homocoupling

Alfonso Garcia-Rubia et al.

CHEMISTRY-A EUROPEAN JOURNAL (2010)

添加到收藏夹

Article Chemistry, Organic

Palladium-Catalyzed Regioselective Oxidative Coupling of Indoles and One-Pot Synthesis of Acetoxylated Biindolyls

Zuijun Liang et al.

JOURNAL OF ORGANIC CHEMISTRY (2010)

添加到收藏夹

Review Biochemistry & Molecular Biology

Synthesis of natural products containing the pyrrolic ring

Ian S. Young et al.

NATURAL PRODUCT REPORTS (2010)

添加到收藏夹

Article Chemistry, Organic

Synthesis of 5,6-dihydropyrrolo[2,1-a]isoquinolines featuring an intramolecular radical-oxidative cyclization of polysubstituted pyrroles, and evaluation of their cytotoxic activity

Paul E. Reyes-Gutierrez et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2010)

添加到收藏夹

Article Chemistry, Organic

An efficient and convenient Cu(OAc)(2)/air mediated oxidative coupling of azoles via C-H activation

Yan Li et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2010)

添加到收藏夹

Article Chemistry, Organic

Iron-catalyzed oxidative homo-coupling of indoles via C-H cleavage

Tianmin Niu et al.

TETRAHEDRON LETTERS (2010)

添加到收藏夹

Article Chemistry, Applied

Ruthenium-Catalyzed Oxidative Homo-Coupling of 2-Arylpyridines

Xiangyu Guo et al.

ADVANCED SYNTHESIS & CATALYSIS (2009)

添加到收藏夹

Article Chemistry, Multidisciplinary

Enantioselective Gold-Catalyzed Allylic Alkylation of Indoles with Alcohols: An Efficient Route to Functionalized Tetrahydrocarbazoles

Marco Bandini et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)

添加到收藏夹

Review Chemistry, Multidisciplinary

Iron(III) chloride in oxidative C-C coupling reactions

Abdelwareth A. O. Sarhan et al.

CHEMICAL SOCIETY REVIEWS (2009)

添加到收藏夹

Article Chemistry, Organic

Synthesis of Biindolizines through Highly Regioselective Palladium-Catalyzed C-H Functionalization

Ji-Bao Xia et al.

JOURNAL OF ORGANIC CHEMISTRY (2009)

添加到收藏夹

Review Chemistry, Multidisciplinary

Lamellarins and related pyrrole-derived alkaloids from marine organisms

Hui Fan et al.

CHEMICAL REVIEWS (2008)

添加到收藏夹

Article Chemistry, Medicinal

Anticancer Alkaloid Lamellarins Inhibit Protein Kinases

Dianne Baunbk et al.

MARINE DRUGS (2008)

添加到收藏夹

Review Chemistry, Multidisciplinary

Organic semiconducting oligomers for use in thin film transistors

Amanda R. Murphy et al.

CHEMICAL REVIEWS (2007)

添加到收藏夹

Article Chemistry, Multidisciplinary

Palladium-catalyzed C-H homocoupling of bromothiophene derivatives and synthetic application to well-defined oligothiophenes

Masabumi Takahashi et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)

添加到收藏夹

Article Chemistry, Organic

Direct synthesis of bipyrroles using phenyliodine bis(trifluoroacetate) with bromotrimethylsilane

T Dohi et al.

ORGANIC LETTERS (2006)

添加到收藏夹

Article Chemistry, Organic

Synthesis of indolo[2,3-a]pyrrolo[3,4-c]carbazoles by oxidative cyclization of bisindolylmaleimides with a rhodium(III)-copper(II) catalytic system

B Witulski et al.

SYNTHESIS-STUTTGART (2005)

添加到收藏夹

Article Chemistry, Multidisciplinary

The synthesis of head-to-tail (H-T) dimers of 3-substituted thiophenes by the hypervalent iodine(III)-induced oxidative biaryl coupling reaction

T Dohi et al.

CHEMICAL COMMUNICATIONS (2005)

添加到收藏夹

Article Chemistry, Multidisciplinary

Palladium-catalyzed C-H homocoupling of thiophenes: Facile construction of bithiophene structure

K Masui et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)

添加到收藏夹

Article Chemistry, Organic

Total synthesis of 5,5′,6,6′-tetrahydroxy-3,3′-biindolyl, the proposed structure of a potent antioxidant found in beetroot (Beta vulgaris)

SPH Mee et al.

TETRAHEDRON (2004)

添加到收藏夹

Review Chemistry, Multidisciplinary

Iron-catalyzed reactions in organic synthesis

C Bolm et al.

CHEMICAL REVIEWS (2004)

添加到收藏夹

Article Chemistry, Physical

Investigation of the palladium catalyzed aromatic coupling of pyridine derivatives

H Hagelin et al.

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL (2000)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.