期刊
TALANTA
卷 260, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.talanta.2023.124638
关键词
Three-dimensional photonic crystal; Aptamer; Aflatoxin B1; Gold nanoparticles; Food samples
As a novel optical responsive material, photonic crystal shows great potential in the recognition and detection of small molecules. In this study, a label-free composite sensor for aflatoxin B1 (AFB1) based on aptamer-functionalized photonic crystal arrays was successfully developed. The sensing system demonstrated a good linearity and ultrasensitive detection to AFB1, with a wide detection range and a low limit of detection.
As a novel optical responsive material, photonic crystal is a promising sensing material in the recognition and detection of small molecules. Herein, a label-free composite sensor for aflatoxin B1 (AFB1) based on aptamer- functionalized photonic crystal arrays was successfully developed. Three-dimensional photonic crystals (3D PhCs) with a controllable number of layers were produced by a layer-by-layer (LBL) approach, and the intro- duction of gold nanoparticles (AuNPs) facilitated the immobilization procedure of recognition element aptamers, thus creating the AFB1 sensing detection system (AFB1-Apt 3D PhCs). The sensing system AFB1-Apt 3D PhCs exhibited a good linearity in the wide range of 1 pg mL-1-100 ng mL-1 AFB1 with a limit of detection (LOD) of 0.28 pg mL-1. Furthermore AFB1-Apt 3D PhC was successfully applied in the determination of AFB1 in the millet and beer samples with good recovery. The sensing system performed ultrasensitive and label-free detection to the target, which could be further applied in the fields of food safety, clinical diagnosis or environmental monitoring, establishing an efficient and rapid universal detection platform.
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