4.6 Review

Prevalence and predictors of long-delayed (> 120 h) chemotherapy-induced nausea and vomiting (CINV)-a systematic review and individual patient data meta-analysis

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Randomized, Double-Blind, Phase III Study of Fosnetupitant Versus Fosaprepitant for Prevention of Highly Emetogenic Chemotherapy-Induced Nausea and Vomiting: CONSOLE

Akito Hata et al.

Summary: This study evaluated the effectiveness and safety of FosNTP compared to FosAPR in preventing highly emetogenic chemotherapy-induced nausea and vomiting. The results showed that FosNTP was noninferior to FosAPR and had a lower risk of injection site reactions.

JOURNAL OF CLINICAL ONCOLOGY (2022)

Article Oncology

Exploratory Analysis Comparing Fosnetupitant Versus Fosaprepitant for Prevention of Highly Emetogenic Chemotherapy-Induced Nausea and Vomiting (CINV): A Randomized, Double-Blind, Phase 3 Study (CONSOLE)

Akito Hata et al.

Summary: This study analyzed the effectiveness of two different intravenous neurokinin 1 receptor antagonists in combination with other drugs for preventing nausea and vomiting. The results showed that one of the drugs was more effective than the other during the extended 7-day period.

ONCOLOGY AND THERAPY (2022)

Article Hematology

Multiple-day administration of fosaprepitant combined with tropisetron and olanzapine improves the prevention of nausea and vomiting in patients receiving chemotherapy prior to autologous hematopoietic stem cell transplant: a retrospective study

Peipei Ye et al.

Summary: This study retrospectively analyzed CINV data in lymphoma and MM patients who received stem cell transplantation after chemotherapy and compared the efficacy and safety of multiple-day administration of fotaprepitant combined with tropisetron and olanzapine (FTO) to a standard regimen of aprepitant, tropisetron, and dexamethasone (ATD). The results showed that FTO treatment had a higher complete response rate in the delayed phase and reduced the percentage of patients unable to eat and the need for rescue medications.

ANNALS OF HEMATOLOGY (2022)

Article Oncology

Chemotherapy-induced nausea and vomiting (CINV) with carboplatin plus pemetrexed or carboplatin plus paclitaxel in patients with lung cancer: a propensity score-matched analysis

Toshinobu Hayashi et al.

Summary: Patients with lung cancer undergoing carboplatin plus pemetrexed (CBDCA+PEM) chemotherapy have a higher risk of delayed nausea compared to those undergoing carboplatin plus paclitaxel (CBDCA+PTX) chemotherapy, while the incidence of vomiting does not significantly differ between the two groups. Female sex, younger age, and CBDCA+PEM regimen are independent risk factors for delayed nausea, while female sex is an independent risk factor for delayed vomiting.

BMC CANCER (2021)

Article Oncology

5HT3RA plus dexamethasone plus aprepitant for controlling delayed chemotherapy-induced nausea and vomiting in colorectal cancer

Toshinobu Hayashi et al.

Summary: The study found that using 1st 5-HT(3)RA+DEX+APR was more effective in controlling delayed chemotherapy-induced nausea and vomiting in colorectal cancer patients undergoing oxaliplatin-based chemotherapy compared to PALO+DEX, with risk factors for delayed nausea and vomiting with PALO+DEX including alcohol consumption, motion sickness, and female sex.

CANCER SCIENCE (2021)

Article Oncology

Intergenerational comparison of 5-HT3RA in the prevention of chemotherapy-induced nausea and vomiting in gastric cancer patients receiving cisplatin-based chemotherapy: an observational study using a Japanese administrative claims database

Yuji Kunitomi et al.

Summary: The second-generation 5-HT(3)RA demonstrated superior efficacy over the first-generation 5-HT(3)RA in delayed emesis during the first cycle of chemotherapy-induced nausea and vomiting. This trend of reduced CINV events in the second group compared to the first group seemed consistent throughout multiple cycles, suggesting a potential benefit of using second-generation 5-HT(3)RA for managing CINV.

SUPPORTIVE CARE IN CANCER (2021)

Review Oncology

Olanzapine for the prophylaxis and rescue of chemotherapy-induced nausea and vomiting: a systematic review, meta-analysis, cumulative meta-analysis and fragility assessment of the literature

Ronald Chow et al.

Summary: This study rigorously reviewed the efficacy and safety of olanzapine in defined hematology oncology settings, finding that olanzapine-containing regimens were superior in prophylactic setting for HEC patients. Administration of olanzapine at a 10-mg dose showed superiority in multiple efficacy endpoints among adults, while further research is needed for MEC patients and lower 5-mg doses of olanzapine.

SUPPORTIVE CARE IN CANCER (2021)

Article Oncology

Incidence of chemotherapy-induced nausea and vomiting among cancer patients receiving moderately to highly emetogenic chemotherapy in cancer centers in Sichuan, China

Yu Sun et al.

Summary: This study aimed to investigate the occurrences of nausea and vomiting in cancer patients undergoing chemotherapy, finding a high incidence of CINV and the possibility of occurrence beyond the risk period. The results suggest that standardized use of antiemetic medications may be key to improving the prevention and control of CINV.

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2021)

Article Oncology

Efficacy of one-day versus multiple-day dexamethasone for chemotherapy-induced nausea and vomiting in lung cancer patients receiving carboplatin-based chemotherapy: a propensity score-matched analysis

Toshinobu Hayashi et al.

Summary: This study evaluated the efficacy of combining 5-HT(3)RA, APR, and DEX on day 1 of CBDCA-based chemotherapy in lung cancer patients. Results showed that the one-day DEX regimen resulted in poorer control of delayed nausea, recommending careful patient selection when considering DEX-sparing strategies.

SUPPORTIVE CARE IN CANCER (2021)

Article Multidisciplinary Sciences

Impact of reducing day 1 dexamethasone dose in anthracycline-containing regimens on acute gastrointestinal symptoms associated with breast cancer treatment

Yoshitaka Saito et al.

Summary: The study evaluated the possibility of reducing dexamethasone dose from 9.9 mg to 6.6 mg in anthracycline-containing regimens for breast cancer treatment. Results showed a lower complete response rate and exacerbated side effects such as nausea and anorexia in the reduced dose group during the acute phase.

SCIENTIFIC REPORTS (2021)

Article Oncology

A Pragmatic Study Evaluating NEPA Versus Aprepitant for Prevention of Chemotherapy-Induced Nausea and Vomiting in Patients Receiving Moderately Emetogenic Chemotherapy

Laurent Zelek et al.

Summary: This study demonstrated the noninferiority of NEPA compared to aprepitant in preventing CINV, with a numerically higher overall complete response rate for NEPA. NEPA's single-dose combination may offer a potential efficacy benefit over the current standard-of-care.

ONCOLOGIST (2021)

Article Oncology

Antiemetic prophylaxis with fosaprepitant and granisetron in pediatric patients undergoing allogeneic hematopoietic stem cell transplantation

Karin Melanie Cabanillas Stanchi et al.

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2020)

Review Oncology

Antiemetics: American Society of Clinical Oncology Clinical Practice Guideline Update

Paul J. Hesketh et al.

JOURNAL OF CLINICAL ONCOLOGY (2017)

Article Oncology

Control of chemotherapy-induced nausea in patients receiving outpatient cancer chemotherapy

Hirotoshi Iihara et al.

INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY (2016)

Article Health Care Sciences & Services

The Effectiveness of Acupressure for the Control and Management of Chemotherapy-Related Acute and Delayed Nausea: A Randomized Controlled Trial

Alexander Molassiotis et al.

JOURNAL OF PAIN AND SYMPTOM MANAGEMENT (2014)

Article Health Care Sciences & Services

Evaluation of Risk Factors Predicting Chemotherapy-Related Nausea and Vomiting: Results From a European Prospective Observational Study

Alexander Molassiotis et al.

JOURNAL OF PAIN AND SYMPTOM MANAGEMENT (2014)

Article Health Care Sciences & Services

Treatment of nausea and emesis during cancer chemotherapy:: Discrepancies between antiemetic effect and well-being

S Börjeson et al.

JOURNAL OF PAIN AND SYMPTOM MANAGEMENT (2002)