期刊
SCIENCE CHINA-CHEMISTRY
卷 66, 期 10, 页码 2847-2851出版社
SCIENCE PRESS
DOI: 10.1007/s11426-023-1798-1
关键词
diphosphine; asymmetric hydrogenation; chiral ligand
A series of novel atropisomeric diphosphine ligands termed TanPhos with a smaller bite angle were synthesized and designed. TanPhos exhibited high reactivity and enantioselectivity in the rhodium-catalyzed asymmetric hydrogenation of α-dehydro amino ketones, achieving up to 99% yield and 99% ee for a wide range of chiral α-amino ketones.
A series of novel atropisomeric diphosphine ligands termed TanPhos were designed and synthesized, which has a smaller bite angle compared with that of other ligands such as BINAP. TanPhos showed high reactivity and enantioselectivity in the rhodium-catalyzed asymmetric hydrogenation of a-dehydro amino ketones, and up 99% yield and 99% ee were obtained for a wide range of chiral & alpha;-amino ketones.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据