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The Long-Term Outcome of Children Conceived Through Assisted Reproductive Technology

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REPRODUCTIVE SCIENCES
卷 -, 期 -, 页码 -

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SPRINGER HEIDELBERG
DOI: 10.1007/s43032-023-01339-0

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Assisted reproductive technologies; Child development; Long-term outcome; Physical development; Psychomotor development

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ART led to the birth of 60,381 infants in Japan in 2020, and this number is expected to rise. Couples using ART are interested in the long-term outcomes of their children, comparing those conceived naturally with those conceived through ART. This study collected data from various observational studies to investigate the relationship between ART and physical and psychomotor developments in children.
Assisted reproductive technology (ART) led to the birth of 60,381 infants in 2020 in Japan. This number is set to increase as the future interest in ART is anticipated to rise. Couples receiving ART are monitoring the outcomes of these treatments to see whether any differences exist between babies conceived naturally and those conceived via ART. This study investigated the relationship between the long-term outcome of children born from ART with a focus on physical and psychomotor developments. A large volume of data concerning each relationship with ART was collected from various observational studies. Several findings indicate that, over time, the physical characteristics of babies born by ART, and those born naturally are comparable. However, some reports indicate that, until they reach school age, there may be a small difference in growth. ART and naturally conceived children do not vary in academic achievement or attention deficit hyperactivity disorder. Taken together, it is difficult to conclude with certainty that ART is the source of these differences since they may arise from the child's genetic factors or their environment.

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