相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Metabolic Activation and DNA Interactions of Carcinogenic N-Nitrosamines to Which Humans Are Commonly Exposed
Yupeng Li et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
Developing Structure-Activity Relationships for N-Nitrosamine Activity
Kevin P. Cross et al.
Computational Toxicology (2021)
Assessing the impact of expert knowledge on ICH M7 (Q)SAR predictions. Is expert review still needed?
P. Suresh Jayasekara et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2021)
Are all nitrosamines concerning? A review of mutagenicity and carcinogenicity data
Andrew Thresher et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2020)
Improvement of quantitative structure-activity relationship (QSAR) tools for predicting Ames mutagenicity: outcomes of the Ames/QSAR International Challenge Project
Masamitsu Honma et al.
MUTAGENESIS (2019)
Principles and procedures for handling out-of-domain and indeterminate results as part of ICH M7 recommended (Q)SAR analyses
Alexander Amberg et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2019)
Distinguishing between expert and statistical systems for application under ICH M7
Chris Barber et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2017)
Evaluation of a statistics-based Ames mutagenicity QSAR model and interpretation of the results obtained
Chris Barber et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2016)
Principles and procedures for implementation of ICH M7 recommended (Q)SAR analyses
Alexander Amberg et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2016)
It's difficult, but important, to make negative predictions
Richard V. Williams et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2016)
Applicability domain: towards a more formal definition
T. Hanser et al.
SAR AND QSAR IN ENVIRONMENTAL RESEARCH (2016)
Do Carboxylic/Sulfonic Acid Halides Really Present a Mutagenic and Carcinogenic Risk as Impurities in Final Drug Products?
Alexander Amberg et al.
ORGANIC PROCESS RESEARCH & DEVELOPMENT (2015)
A practical application of two in silico systems for identification of potentially mutagenic impurities
Nigel Greene et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2015)
(Q)SAR assessments of potentially mutagenic impurities: A regulatory perspective on the utility of expert knowledge and data submission
Mark W. Powley
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2015)
Establishing best practise in the application of expert review of mutagenicity under ICH M7
Chris Barber et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2015)
Use of in silico systems and expert knowledge for structure-based assessment of potentially mutagenic impurities
Andreas Sutter et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2013)
Assessing confidence in predictions made by knowledge-based systems
Philip N. Judson et al.
TOXICOLOGY RESEARCH (2013)
(Q)SAR Modelling and Safety Assessment in Regulatory Review
N. L. Kruhlak et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2012)
In silico methods combined with expert knowledge rule out mutagenic potential of pharmaceutical impurities: An industry survey
Krista L. Dobo et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2012)
An evaluation of the common mechanism approach to the Food Quality Protection Act: Captan and four related fungicides, a practical example
BK Bernard et al.
INTERNATIONAL JOURNAL OF TOXICOLOGY (2000)