期刊
MOLECULES
卷 21, 期 3, 页码 -出版社
MDPI
DOI: 10.3390/molecules21030276
关键词
pyrazole oxime; 5-trifluoromethylpyridyl; synthesis; bioactivity
资金
- National Natural Science Foundation of China [21202089, 21372135]
- Research Foundation of the Six People Peak of Jiangsu Province [2013-SWYY-013]
- Natural Science Foundation of Jiangsu Province [BK20140425]
- Technology Project Fund of Nantong City [CP12013002, AS2014011, MS22015020]
In this study, in order to find novel biologically active pyrazole oxime compounds, a series of pyrazole oxime derivatives containing a 5-trifluoromethylpyridyl moiety were synthesized. Preliminary bioassays indicated that most title compounds were found to display good to excellent acaricidal activity against Tetranychus cinnabarinus at a concentration of 200 g/mL, and some designed compounds still showed excellent acaricidal activity against Tetranychus cinnabarinus at the concentration of 10 g/mL, especially since the inhibition rates of compounds 8e, 8f, 8l, 8m, 8n, 8p, and 8q were all 100.00%. Interestingly, some target compounds exhibited moderate to good insecticidal activities against Plutella xylostella and Aphis craccivora at a concentration of 200 g/mL; furthermore, compounds 8e and 8l possessed outstanding insecticidal activities against Plutella xylostella under the concentration of 50 g/mL.
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